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Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in recent years. Due to the inherent tissue topography variability, accurate autofocusing remains a critical challenge for WSI and automated microscopy…

Extracting reliable and quantitative microstructure information of living tissue by non-invasive imaging is an outstanding challenge for understanding disease mechanisms and allowing early stage diagnosis of pathologies. Magnetic Resonance…

Medical Physics · Physics 2021-07-12 Milena Capiglioni , Analia Zwick , Pablo Jimenez , Gonzalo A. Alvarez

Applying convolutional neural networks to large images is computationally expensive because the amount of computation scales linearly with the number of image pixels. We present a novel recurrent neural network model that is capable of…

Machine Learning · Computer Science 2014-06-25 Volodymyr Mnih , Nicolas Heess , Alex Graves , Koray Kavukcuoglu

Two-dimensional (2D) freehand ultrasonography is one of the most commonly used medical imaging modalities, particularly in obstetrics and gynaecology. However, it only captures 2D cross-sectional views of inherently 3D anatomies, losing…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Mark C. Eid , Pak-Hei Yeung , Madeleine K. Wyburd , João F. Henriques , Ana I. L. Namburete

Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz

In vision-enabled autonomous systems such as robots and autonomous cars, video object detection plays a crucial role, and both its speed and accuracy are important factors to provide reliable operation. The key insight we show in this paper…

Computer Vision and Pattern Recognition · Computer Science 2019-02-11 Ting-Wu Chin , Ruizhou Ding , Diana Marculescu

Supervised deep learning approaches can artificially increase the resolution of microscopy images by learning a mapping between two image resolutions or modalities. However, such methods often require a large set of hard-to-get…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Marzieh Gheisari , Auguste Genovesio

Traditional fluorescence microscopy is constrained by inherent trade-offs among resolution, field-of-view, and system complexity. To navigate these challenges, we introduce a simple and low-cost computational multi-aperture miniature…

Optics · Physics 2024-05-31 Qianwan Yang , Ruipeng Guo , Guorong Hu , Yujia Xue , Yunzhe Li , Lei Tian

Advances in deep learning for natural images have prompted a surge of interest in applying similar techniques to medical images. The majority of the initial attempts focused on replacing the input of a deep convolutional neural network with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Krzysztof J. Geras , Stacey Wolfson , Yiqiu Shen , Nan Wu , S. Gene Kim , Eric Kim , Laura Heacock , Ujas Parikh , Linda Moy , Kyunghyun Cho

A lensless digital holography enables wide-field microscopic imaging without the limitations imposed by optical lens performance. However, conventional holographic imaging often relies on magnifying optical systems to compensate for the low…

Optics · Physics 2025-06-24 Byung Gyu Chae

Magnetic resonance imaging (MRI) is the cornerstone technique for diagnostic medicine, biology, and neuroscience. This imaging method is highly innovative, noninvasive and its impact continues to grow. It can be used for measuring changes…

X-Ray image enhancement, along with many other medical image processing applications, requires the segmentation of images into bone, soft tissue, and open beam regions. We apply a machine learning approach to this problem, presenting an…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Joseph Bullock , Carolina Cuesta-Lazaro , Arnau Quera-Bofarull

The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Aniket Pramanik , Xiaodong Wu , Mathews Jacob

Over the last ten years, developments in whole-brain microscopy now allow for high-resolution imaging of intact brains of small rodents such as mice. These complex images contain a wealth of information, but many neuroscience laboratories…

Neurons and Cognition · Quantitative Biology 2021-02-24 Adam L Tyson , Troy W Margrie

Successful fine-grained image classification methods learn subtle details between visually similar (sub-)classes, but the problem becomes significantly more challenging if the details are missing due to low resolution. Encouraged by the…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Dingding Cai , Ke Chen , Yanlin Qian , Joni-Kristian Kämäräinen

An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking…

The main disadvantage of Magnetic Resonance Imaging (MRI) are its long scan times and, in consequence, its sensitivity to motion. Exploiting the complementary information from multiple receive coils, parallel imaging is able to recover…

Numerical Analysis · Computer Science 2017-03-07 Martin Uecker

In x-ray microscopy, traditional raster-scanning techniques are used to acquire a microscopic image in a series of step-scans. Alternatively, scanning the x-ray probe along a continuous path, called a fly-scan, reduces scan time and…

Image and Video Processing · Electrical Eng. & Systems 2025-09-23 Yu Lu , Thomas F. Lynn , Ming Du , Zichao Di , Sven Leyffer

Acquiring images in high resolution is often a challenging task. Especially in the medical sector, image quality has to be balanced with acquisition time and patient comfort. To strike a compromise between scan time and quality for Magnetic…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Maja Schlereth , Moritz Schillinger , Katharina Breininger

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu