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During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

Biological Physics · Physics 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner

We use probabilistic methods to study properties of mean-field models, arising as large-scale limits of certain particle systems with mean-field interaction. The underlying particle system is such that $n$ particles move forward on the real…

Probability · Mathematics 2022-04-19 Alexander Stolyar

Metabolic reactions of single-cell organisms are routinely observed to become dispensable or even incapable of carrying activity under certain circumstances. Yet, the mechanisms as well as the range of conditions and phenotypes associated…

Molecular Networks · Quantitative Biology 2009-01-21 Takashi Nishikawa , Natali Gulbahce , Adilson E. Motter

Because active particles break time-reversal symmetry, a single non-spherical body placed in an active fluid generates currents. We show that when two or more passive bodies are placed in an active fluid these currents lead to long-range…

Statistical Mechanics · Physics 2018-02-07 Yongjoo Baek , Alexandre P. Solon , Xinpeng Xu , Nikolai Nikola , Yariv Kafri

Emergent behavior in active systems is a complex byproduct of local, often pairwise, interactions. One such interaction is self-avoidance, which experimentally can arise as a response to self-generated environmental signals; such…

Soft Condensed Matter · Physics 2024-03-29 Katherine Daftari , Katherine Newhall

Many aquatic organisms exhibit remarkable abilities to detect and track chemical signals when foraging, mating and escaping. For example, the male copepod { \em T. longicornis} identifies the female in the open ocean by following its…

Biological Physics · Physics 2017-01-27 Yangyang Huang , Jeannette Yen , Eva Kanso

The transport of self-propelled particles such as bacteria and phoretic swimmers through crowded heterogeneous environments is relevant to many natural and engineering processes, from biofilm formation and contamination processes to…

Fluid Dynamics · Physics 2019-04-10 Roberto Alonso-Matilla , Brato Chakrabarti , David Saintillan

An artificial microswimmer drifts in response to spatio-temporal modulations of an activating suspension medium. We consider two competing mechanisms capable of influencing its tactic response: angular fluctuations, which help it explore…

Soft Condensed Matter · Physics 2017-02-15 Alexander Geiseler , Peter Hänggi , Fabio Marchesoni

Many insects like ants communicate chemically via chemotaxis. This allows them to build large trail systems which in many respects are similar to human-build highway networks. Using a recently proposed stochastic cellular automaton model we…

Statistical Mechanics · Physics 2007-05-23 Andreas Schadschneider , Debashish Chowdhury , Alexander John , Katsuhiro Nishinari

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

Diagonal or chevron patterns are known to spontaneously emerge at the intersection of two perpendicular flows of self-propelled particles, e.g. pedestrians. The instability responsible for this pattern formation has been studied in previous…

Statistical Mechanics · Physics 2015-06-15 Julien Cividini , Cecile Appert-Rolland

Combining experiments and theory, we address the dynamics of self-propelled particles in crowded environments. We first demonstrate that motile colloids cruising at constant speed through random lattices undergo a smooth transition from…

Soft Condensed Matter · Physics 2017-11-01 Alexandre Morin , David Lopes Cardozo , Vijayakumar Chikkadi , Denis Bartolo

Motivated by experimental results on the interplay between molecular motors and tau proteins, we extend lattice-based models of intracellular transport to include a second species of particle which locally influences the motor-filament…

Subcellular Processes · Quantitative Biology 2010-04-27 H. Grzeschik , R. J. Harris , L. Santen

We study coupled transport in the nonequilibrium stationary state of a model consisting of independent random walkers, moving along a one-dimensional channel, which carry a conserved energy-like quantity, with density and temperature…

Statistical Mechanics · Physics 2009-08-11 Hernán Larralde , David P. Sanders

Multicellular self-organization drives development in biological organisms, yet a comprehensive theory is lacking as basic properties of cells can complicate common approaches. Framing such properties by dynamic graphs led to new…

Molecular Networks · Quantitative Biology 2026-05-26 Kyle R. Allison

The past two decades have seen a remarkable progress in the development of synthetic colloidal agents which are capable of creating directed motion in an unbiased environment at the microscale. These self-propelling particles are often…

Soft Condensed Matter · Physics 2023-02-10 Benno Liebchen , Aritra K. Mukhopadhyay

Development in multi-cellular organisms is marked by a high degree of spatial organization of the cells attaining distinct fates in the embryo. We show that receptor-ligand interaction between cells in close physical proximity adaptively…

Tissues and Organs · Quantitative Biology 2021-06-30 Chandrashekar Kuyyamudi , Shakti N. Menon , Sitabhra Sinha

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

Soft Condensed Matter · Physics 2016-04-20 Nicolas Bruot , Pietro Cicuta

Contact between particles and motile cells underpins a wide variety of biological processes, from nutrient capture and ligand binding, to grazing, viral infection and cell-cell communication. The window of opportunity for these interactions…

Biological Physics · Physics 2018-03-28 Arnold Mathijssen , Raphaël Jeanneret , Marco Polin

A spacially extended model of the collective behavior of a large number of locally acting organisms is proposed in which organisms move probabilistically between local cells in space, but with weights dependent on local morphogenetic…

adap-org · Physics 2008-06-25 Mark M. Millonas