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We consider a bivariate first hitting-time model in which durations are the crossing times of dependent compound Poisson processes with fixed thresholds. The identifiability of the model is discussed, and likelihood estimators of the model…

Methodology · Statistics 2025-04-14 Mikael Escobar-Bach , Alexandre Popier , Malo Sahin

Neurons in the nervous system convey information to higher brain regions by the generation of spike trains. An important question in the field of computational neuroscience is how these sensory neurons encode environmental information in a…

Neurons and Cognition · Quantitative Biology 2013-09-13 Alex Susemihl , Ron Meir , Manfred Opper

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

Spiking neural networks (SNNs) are posited as a computationally efficient and biologically plausible alternative to conventional neural architectures, with their core computational framework primarily using the leaky integrate-and-fire…

Neural and Evolutionary Computing · Computer Science 2025-03-18 Malyaban Bal , Abhronil Sengupta

We present rigorous results for the mean first passage time and first passage time statistics for two-channel Markov additive diffusion in a 3-dimensional spherical domain. Inspired by biophysical examples we assume that the particle can…

Statistical Mechanics · Physics 2017-02-01 Aljaz Godec , Ralf Metzler

Advances in neuroscience have enabled researchers to measure the activities of large numbers of neurons simultaneously in behaving animals. We have access to the fluorescence of each of the neurons which provides a first-order approximation…

Neurons and Cognition · Quantitative Biology 2023-07-21 Abhisek Chakraborty

The computation performed by a neuron can be formulated as a combination of dimensional reduction in stimulus space and the nonlinearity inherent in a spiking output. White noise stimulus and reverse correlation (the spike-triggered average…

Biological Physics · Physics 2007-05-23 Blaise Aguera y Arcas , Adrienne Fairhall

Redundant information transfer in a neural network can increase the complexity of the deep learning model, thus increasing its power consumption. We introduce in this paper a novel spiking neuron, termed Variable Spiking Neuron (VSN), which…

Neural and Evolutionary Computing · Computer Science 2023-11-17 Shailesh Garg , Souvik Chakraborty

We study the mean time for a random walk to traverse between two arbitrary sites of the Erdos-Renyi random graph. We develop an effective medium approximation that predicts that the mean first-passage time between pairs of nodes, as well as…

Statistical Mechanics · Physics 2009-11-10 V. Sood , S. Redner , D. ben-Avraham

Neuronal dynamics is driven by externally imposed or internally generated random excitations/noise, and is often described by systems of random or stochastic ordinary differential equations. Such systems admit a distribution of solutions,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Tyler E. Maltba , Hongli Zhao , Daniel M. Tartakovsky

We study mean-field descriptions for spatially-extended networks of linear (leaky) and quadratic integrate-and-fire neurons with stochastic spiking times. We consider large-population limits of continuous-time Galves-L\"ocherbach (GL)…

Probability · Mathematics 2025-02-06 Daniele Avitabile , Michel Davydov

Bayesian inference provides a principled framework for understanding brain function, while neural activity in the brain is inherently spike-based. This paper bridges these two perspectives by designing spiking neural networks that simulate…

Neurons and Cognition · Quantitative Biology 2026-01-01 Sepideh Adamiat , Wouter M. Kouw , Bert de Vries

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the…

Neurons and Cognition · Quantitative Biology 2024-01-09 Afifurrahman , Mohd Hafiz Mohd , Farah Aini Abdullah

This article presents a biological neural network model driven by inhomogeneous Poisson processes accounting for the intrinsic randomness of synapses. The main novelty is the introduction of local interactions: each firing neuron triggers…

Probability · Mathematics 2021-08-17 Maximiliano Altamirano , Roberto Cortez , Matthieu Jonckheere , Lasse Leskelä

Spiking neural networks can compensate for quantization error by encoding information either in the temporal domain, or by processing discretized quantities in hidden states of higher precision. In theory, a wide dynamic range state-space…

Neural and Evolutionary Computing · Computer Science 2022-01-31 Jason K. Eshraghian , Wei D. Lu

The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been…

Neurons and Cognition · Quantitative Biology 2024-05-27 Kevin S. Chen , Ying-Jen Yang

We study the mean-field limit of a model of biological neuron networks based on the so-called stochastic integrate-and-fire (IF) dynamics. Our approach allows to derive a continuous limit for the macroscopic behavior of the system, the…

Probability · Mathematics 2023-09-11 Pierre-Emmanuel Jabin , Datong Zhou

The meta distribution of the signal-to-interference-ratio (SIR) is an important performance indicator for wireless networks because, for ergodic point processes, it describes the fraction of scheduled links that achieve certain reliability,…

Information Theory · Computer Science 2020-08-27 Konstantinos Koufos , Carl P. Dettmann

Piecewise Diffusion Markov Processes (PDifMPs) are valuable for modelling systems where continuous dynamics are interrupted by sudden shifts and/or changes in drift and diffusion. The first-passage time (FPT) in such models plays a central…

Probability · Mathematics 2025-07-11 Sascha Desmettre , Devika Khurana , Amira Meddah

Conventional analysis of neuroscience data involves computing average neural activity over a group of trials and/or a period of time. This approach may be particularly problematic when assessing the response patterns of neurons to more than…