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In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

Automation-assisted cervical screening via Pap smear or liquid-based cytology (LBC) is a highly effective cell imaging based cancer detection tool, where cells are partitioned into "abnormal" and "normal" categories. However, the success of…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Ling Zhang , Le Lu , Isabella Nogues , Ronald M. Summers , Shaoxiong Liu , Jianhua Yao

Automated detection and classification of cervical cells in conventional Pap smear images can strengthen cervical cancer screening at scale by reducing manual workload, improving triage, and increasing consistency across readers. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Lautaro Kogan , María Victoria Ríos

Screening is critical for prevention and early detection of cervical cancer but it is time-consuming and laborious. Supervised deep convolutional neural networks have been developed to automate pap smear screening and the results are…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Yu Ando , Nora Jee-Young Park and , Gun Oh Chong , Seokhwan Ko , Donghyeon Lee , Junghwan Cho , Hyungsoo Han

Overlapping of cervical cells and poor contrast of cell cytoplasm are the major issues in accurate detection and segmentation of cervical cells. An unsupervised cell segmentation approach is presented here. Cell clump segmentation was…

Computer Vision and Pattern Recognition · Computer Science 2015-05-22 S L Happy , Swarnadip Chatterjee , Debdoot Sheet

Early detection of cervical cancer is crucial for improving patient outcomes and reducing mortality by identifying precancerous lesions as soon as possible. As a result, the use of pap smear screening has significantly increased, leading to…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Theo Di Piazza , Loic Boussel

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Haoming Lin , Yuyang Hu , Siping Chen , Jianhua Yao , Ling Zhang

Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nisreen Albzour , Sarah S. Lam

Screening Papanicolaou test samples has proven to be highly effective in reducing cervical cancer-related mortality. However, the lack of trained cytopathologists hinders its widespread implementation in low-resource settings. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Thomas Stegmüller , Christian Abbet , Behzad Bozorgtabar , Holly Clarke , Patrick Petignat , Pierre Vassilakos , Jean-Philippe Thiran

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

While most previous automation-assisted reading methods can improve efficiency, their performance often relies on the success of accurate cell segmentation and hand-craft feature extraction. This paper presents an efficient and totally…

Computer Vision and Pattern Recognition · Computer Science 2019-12-17 Yao Xiang , Wanxin Sun , Changli Pan , Meng Yan , Zhihua Yin , Yixiong Liang

Archiving large sets of medical or cell images in digital libraries may require ordering randomly scattered sets of image data according to specific criteria, such as the spatial extent of a specific local color or contrast content that…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 John M. Wandeto , Birgitta Dresp-Langley

Due to its specificity, fluorescence microscopy (FM) has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit FM's utility. Recently, it has been shown that…

Analyzing Pap cytology slides is an important tasks in detecting and grading precancerous and cancerous cervical cancer stages. Processing cytology images usually involve segmenting nuclei and overlapping cells. We introduce a cervical…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Hady Ahmady Phoulady , Peter R. Mouton

Cervical cancer is the seventh most common cancer among all the cancers worldwide and the fourth most common cancer among women. Cervical cytopathology image classification is an important method to diagnose cervical cancer. Manual…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Wanli Liu , Chen Li , Ning Xu , Tao Jiang , Md Mamunur Rahaman , Hongzan Sun , Xiangchen Wu , Weiming Hu , Haoyuan Chen , Changhao Sun , Yudong Yao , Marcin Grzegorzek

Pap smear testing has been widely used for detecting cervical cancers based on the morphology properties of cell nuclei in microscopic image. An accurate nuclei segmentation could thus improve the success rate of cervical cancer screening.…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Jie Zhao , Quanzheng Li , Xiang Li , Hongfeng Li , Li Zhang

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

Cervical cancer, one of the most common fatal cancers among women, can be prevented by regular screening to detect any precancerous lesions at early stages and treat them. Pap smear test is a widely performed screening technique for early…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Md Mamunur Rahaman , Chen Li , Yudong Yao , Frank Kulwa , Xiangchen Wu , Xiaoyan Li , Qian Wang

Cytology screening from Papanicolaou (Pap) smears is a common and effective tool for the preventive clinical management of cervical cancer, where abnormal cell detection from whole slide images serves as the foundation for reporting…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Hao Jiang , Runsheng Liu , Yanning Zhou , Huangjing Lin , Hao Chen

Cervical cancer remains a significant health problem, especially in developing countries. Early detection is critical for effective treatment. Convolutional neural networks (CNN) have shown promise in automated cervical cancer screening,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Ach Khozaimi , Isnani Darti , Syaiful Anam , Wuryansari Muharini Kusumawinahyu
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