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In current medical practice, patients undergoing depression treatment must wait four to six weeks before a clinician can assess medication response due to the delayed noticeable effects of antidepressants. Identification of a treatment…

Machine Learning · Computer Science 2025-01-09 Melanija Kraljevska , Katerina Hlavackova-Schindler , Lukas Miklautz , Claudia Plant

Electroencephalogram (EEG) provides noninvasive measures of brain activity and is found to be valuable for diagnosis of some chronic disorders. Specifically, pre-treatment EEG signals in alpha and theta frequency bands have demonstrated…

Applications · Statistics 2023-05-24 Bin Yang , Xingche Guo , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Current diagnostic practice in psychiatry is not relying on objective biophysical evidence. Recent pandemic emphasized the need to address the rising number of mood disorders (in particular, depression) cases in a more efficient way. We are…

Neurons and Cognition · Quantitative Biology 2021-10-26 Milena B. Čukić

Timely and objective screening of major depressive disorder (MDD) is vital, yet diagnosis still relies on subjective scales. Electroencephalography (EEG) provides a low-cost biomarker, but existing deep models treat spectra as static…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Jingru Qiu , Jiale Liang , Xuanhan Fan , Mingda Zhang , Zhenli He

Background and Objective: The connection between depression and autonomous nervous system (ANS) is well documented in scientific literature. Heart rate variability (HRV) is a rich source of information for studying the dynamics of this…

Neurons and Cognition · Quantitative Biology 2021-10-19 Milena Čukić , Danka Savić , Julia Sidorova

In this paper, we aimed at reviewing present literature on employing nonlinear analysis in combination with machine learning methods, in depression detection or prediction task. We are focusing on an affordable data-driven approach,…

Signal Processing · Electrical Eng. & Systems 2019-09-10 Milena Čukić Radenković , Victoria Lopez Lopez

Mental disorders represent critical public health challenges as they are leading contributors to the global burden of disease and intensely influence social and financial welfare of individuals. The present comprehensive review concentrate…

Neurons and Cognition · Quantitative Biology 2021-02-05 Sana Yasin , Syed Asad Hussain , Sinem Aslan , Imran Raza , Muhammad Muzammel , Alice Othmani

Invasive electroencephalograph (EEG) recordings of ten patients suffering from focal epilepsy were analyzed using the method of renormalized entropy. Introduced as a complexity measure for the different regimes of a dynamical system, the…

Medical Physics · Physics 2009-10-31 K. Kopitzki , P. C. Warnke , J. Timmer

In the status quo, dementia is yet to be cured. Precise diagnosis prior to the onset of the symptoms can prevent the rapid progression of the emerging cognitive impairment. Recent progress has shown that Electroencephalography (EEG) is the…

Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…

Human-Computer Interaction · Computer Science 2025-12-30 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta

An electroencephalogram (EEG) records the spatially averaged electrical activity of neurons in the brain, measured from the human scalp. Prior studies have explored EEG-based classification of objects or concepts, often for passive viewing…

Machine Learning · Computer Science 2026-02-25 Anupam Sharma , Harish Katti , Prajwal Singh , Shanmuganathan Raman , Krishna Miyapuram

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Quantifying the complex/multifractal organization of the brain signals is crucial to fully understanding the brain processes and structure. In this contribution, we performed the multifractal analysis of the electroencephalographic (EEG)…

Characterizing the brain dynamics during different cortical states can reveal valuable information about its patterns across various cognitive processes. In particular, studying the differences between awake and sleep stages can shed light…

The generalization and robustness of an electroencephalogram (EEG)-based computer aided diagnostic system are crucial requirements in actual clinical practice. To reach these goals, we propose a new EEG representation that provides a more…

Machine Learning · Computer Science 2017-02-10 Khadijeh Sadatnejad , Saeed S. Ghidary , Reza Rostami , Reza Kazemi

Real-time fMRI neurofeedback (rtfMRI-nf) is an emerging approach for studies and novel treatments of major depressive disorder (MDD). EEG performed simultaneously with an rtfMRI-nf procedure allows an independent evaluation of rtfMRI-nf…

Simultaneous real-time fMRI and EEG neurofeedback (rtfMRI-EEG-nf) is an emerging neuromodulation approach, that enables simultaneous volitional regulation of both hemodynamic (BOLD fMRI) and electrophysiological (EEG) brain activities. Here…

Neurons and Cognition · Quantitative Biology 2020-07-06 Vadim Zotev , Ahmad Mayeli , Masaya Misaki , Jerzy Bodurka

Emotional recognition through exploring the electroencephalography (EEG) characteristics has been widely performed in recent studies. Nonlinear analysis and feature extraction methods for understanding the complex dynamical phenomena are…

Signal Processing · Electrical Eng. & Systems 2022-05-10 Yan Yan , Xuankun Wu , Chengdong Li , Yini He , Zhicheng Zhang , Huihui Li , Ang Li , Lei Wang

Resting state electroencephalogram (EEG) abnormalities in clinically high-risk individuals (CHR), clinically stable first-episode patients with schizophrenia (FES), healthy controls (HC) suggest alterations in neural oscillatory activity.…

Signal Processing · Electrical Eng. & Systems 2018-01-18 Haichun Liu , TianHong Zhang , Yumeng Ye , Changchun Pan , Genke Yang , JiJun Wang , Robert C. Qiu

Current source density (CSD) power asymmetry, a measure derived from electroencephalography (EEG), is a potential biomarker for major depressive disorder (MDD). Though this measure is functional in nature (defined on the frequency domain),…

Applications · Statistics 2020-12-07 Adam Ciarleglio , Eva Petkova , Ofer Harel