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This article describes an improved brute-force solving strategy for Quadratic Unconstrained Binary Optimization (QUBO) problems that is faster than naive approaches and easily parallelizable. It exploits the Gray code ordering of natural…

Data Structures and Algorithms · Computer Science 2023-10-31 Sascha Mücke

Obtaining Quadratic Unconstrained Binary Optimisation models for various optimisation problems, in order to solve those on physical quantum computers (such as the the DWave annealers) is nowadays a lengthy and tedious process that requires…

Mathematical Software · Computer Science 2023-07-20 Armin Wolf , Cristian Grozea

The field of Quantum Computing has gathered significant popularity in recent years and a large number of papers have studied its effectiveness in tackling many tasks. We focus in particular on Quantum Annealing (QA), a meta-heuristic solver…

Quantum Physics · Physics 2026-03-03 Riccardo Pellini , Maurizio Ferrari Dacrema

The reconstruction of charged particles will be a key computing challenge for the high-luminosity Large Hadron Collider (HL-LHC) where increased data rates lead to large increases in running time for current pattern recognition algorithms.…

Quantum Physics · Physics 2019-02-25 Frederic Bapst , Wahid Bhimji , Paolo Calafiura , Heather Gray , Wim Lavrijsen , Lucy Linder

We introduce a physics-inspired continuous relaxation framework that yields substantially improved solutions for NP-hard combinatorial optimization problems, including Quadratic Unconstrained Binary Optimization (QUBO), binary sparse…

Statistical Mechanics · Physics 2026-05-26 Khen Cohen , Mark Glass , Meir Feder , Yaron Oz

Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing are prominent approaches for solving combinatorial optimization problems, such as those formulated as Quadratic Unconstrained Binary Optimization (QUBO). These…

A black-box optimization algorithm such as Bayesian optimization finds extremum of an unknown function by alternating inference of the underlying function and optimization of an acquisition function. In a high-dimensional space, such…

Quantum Physics · Physics 2021-05-03 Syun Izawa , Koki Kitai , Shu Tanaka , Ryo Tamura , Koji Tsuda

Using Quantum Computers to solve problems in Recommender Systems that classical computers cannot address is a worthwhile research topic. In this paper, we use Quantum Annealers to address the feature selection problem in recommendation…

Information Retrieval · Computer Science 2024-07-04 Jiayang Niu , Jie Li , Ke Deng , Yongli Ren

Quadratic Unconstrained Binary Optimization (QUBO) problems are NP-hard problems and many real-world problems can be formulated as QUBO. Currently there are no algorithms known that can solve arbitrary instances of NP-hard problems…

Quantum Physics · Physics 2023-12-20 Christian Münch , Fritz Schinkel , Sebastian Zielinski , Stefan Walter

This paper presents a new method to reduce the optimization of a pseudo-Boolean function to QUBO problem which can be solved by quantum annealer. The new method has two aspects, one is coefficient optimization and the other is variable…

Cryptography and Security · Computer Science 2022-11-21 Anpeng Zhang , Xiutao Feng

Feature selection is a machine learning technique for identifying relevant variables in classification and regression models. In single-cell RNA sequencing (scRNA-seq) data analysis, feature selection is used to identify relevant genes that…

Genomics · Quantitative Biology 2025-12-02 Selim Romero , Shreyan Gupta , Victoria Gatlin , Robert S. Chapkin , James J. Cai

A quantum annealer heuristically minimizes quadratic unconstrained binary optimization (QUBO) problems, but is limited by the physical hardware in the size and density of the problems it can handle. We have developed a meta-heuristic solver…

Discrete Mathematics · Computer Science 2016-05-20 Gili Rosenberg , Mohammad Vazifeh , Brad Woods , Eldad Haber

Quadratic Unconstrained Binary Optimization (QUBO) is a combinatorial optimization to find an optimal binary solution vector that minimizes the energy value defined by a quadratic formula of binary variables in the vector. As many NP-hard…

Performance · Computer Science 2023-10-19 Koji Nakano , Daisuke Takafuji , Yasuaki Ito , Takashi Yazane , Junko Yano , Shiro Ozaki , Ryota Katsuki , Rie Mori

Computed tomography (CT) is an important imaging technique used in medical analysis of the internal structure of the human body. Previously, image segmentation methods were required after acquiring reconstructed CT images to obtain…

Quantum Physics · Physics 2024-09-17 Kyungtaek Jun

This paper proposes a hybrid quantum-classical algorithm to solve a fundamental power system problem called unit commitment (UC). The UC problem is decomposed into a quadratic subproblem, a quadratic unconstrained binary optimization (QUBO)…

Quantum Physics · Physics 2022-04-19 Reza Mahroo , Amin Kargarian

3SAT instances need to be transformed into instances of Quadratic Unconstrained Binary Optimization (QUBO) to be solved on a quantum annealer. Although it has been shown that the choice of the 3SAT-to-QUBO transformation can impact the…

From the perspective of global warming, efficiency improvement of power grids is a pressing issue. Power grids have many switching devices to control the flow of electricity. Since there is a slight resistance in the wires and power…

Quantum Physics · Physics 2023-05-16 Masaya Takahashi , Hiroaki Nishioka , Masahiro Hirai , Hidetaka Takano

Monte Carlo (MC) reinforcement learning suffers from high sample complexity, especially in environments with sparse rewards, large state spaces, and correlated trajectories. We address these limitations by reformulating episode selection as…

Machine Learning · Computer Science 2026-01-27 Hadi Salloum , Ali Jnadi , Yaroslav Kholodov , Alexander Gasnikov

Combinatorial optimization problems, integral to various scientific and industrial applications, often vary significantly in their complexity and computational difficulty. Transforming such problems into Quadratic Unconstrained Binary…

Quantum Physics · Physics 2024-04-04 Thore Gerlach , Sascha Mücke

Ising machines are next-generation computers expected to efficiently sample near-optimal solutions of combinatorial optimization problems. Combinatorial optimization problems are modeled as quadratic unconstrained binary optimization (QUBO)…

Optimization and Control · Mathematics 2024-06-21 Kentaro Ohno , Nozomu Togawa