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Portable, ultra-low-field (ULF) magnetic resonance imaging has the potential to expand access to neuroimaging but currently suffers from coarse spatial and angular resolutions and low signal-to-noise ratios. Diffusion tensor imaging (DTI),…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Mark D. Olchanyi , Annabel Sorby-Adams , John Kirsch , Brian L. Edlow , Ava Farnan , Renfei Liu , Matthew S. Rosen , Emery N. Brown , W. Taylor Kimberly , Juan Eugenio Iglesias

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

Multi-contrast magnetic resonance imaging (MRI) is the most common management tool used to characterize neurological disorders based on brain tissue contrasts. However, acquiring high-resolution MRI scans is time-consuming and infeasible…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Ye Mao , Lan Jiang , Xi Chen , Chao Li

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

Distal myopathy represents a genetically heterogeneous group of skeletal muscle disorders with broad clinical manifestations, posing diagnostic challenges in radiology. To address this, we propose a novel multimodal attention-aware fusion…

Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Tongda Xu , Xiyan Cai , Yao Wang , Xiuyuan Wang , Sohae Chung , Els Fieremans , Joseph Rath , Steven Flanagan , Yvonne W Lui

Diffusion MRI offers a unique probe into neural microstructure and connectivity in the developing brain. However, analysis of neonatal brain imaging data is complicated by inevitable subject motion, leading to a series of scattered slices…

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…

Medical Physics · Physics 2024-08-21 Ting Gong , Merlin J. Fair , Kawin Setsompop , Hui Zhang

Diffusion-weighted magnetic resonance imaging (DW-MRI) derived scalar maps are effective for assessing neurodegenerative diseases and microstructural properties of white matter in large number of brain conditions. However, DW-MRI inherently…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Gabriel Girard , Manon Edde , Félix Dumais , Yoan David , Matthieu Dumont , Guillaume Theaud , Jean-Christophe Houde , Arnaud Boré , Maxime Descoteaux , Pierre-Marc Jodoin

High-resolution diffusion tensor imaging (DTI) is beneficial for probing tissue microstructure in fine neuroanatomical structures, but long scan times and limited signal-to-noise ratio pose significant barriers to acquiring DTI at…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Chanon Ngamsombat , Yuxin Hu , Congyu Liao , Fuyixue Wang , Kawin Setsompop , Jonathan R. Polimeni , Berkin Bilgic , Susie Y. Huang

Multiple Sclerosis is a chronic autoimmune disorder characterized by the degradation of the myelin sheath in the central nervous system, leading to neurological impairments. In this work, we analyze a reaction-diffusion model derived from…

Tissues and Organs · Quantitative Biology 2026-03-10 Romina Travaglini , Rossella Della Marca

Many developmental processes, such as plasticity and aging, or pathological processes such as neurological diseases are characterized by modulations of specific cellular types and their microstructures. Diffusion-weighted Magnetic Resonance…

Medical Physics · Physics 2019-03-26 Marco Palombo , Noam Shemesh , Itamar Ronen , Julien Valette

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

Head motion is inevitable in the acquisition of diffusion-weighted images, especially for certain motion-prone subjects and for data gathering of advanced diffusion models with prolonged scan times. Deficient accuracy of motion correction…

Medical Physics · Physics 2019-05-31 Ting Gong , Qiqi Tong , Hongjian He , Zhiwei Li , Jianhui Zhong

In this paper, we propose a method for denoising diffusion-weighted images (DWI) of the brain using a convolutional neural network trained on realistic, synthetic MR data. We compare our results to averaging of repeated scans, a widespread…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Kamil Gorczewski , Kamil Cepuch , Agata Zawadzka

Diffusion Magnetic Resonance Imaging (dMRI) is sensitive to white matter (WM) changes across the human lifespan. Several models have been proposed to provide more specific metrics than those provided by the conventional Diffusion Tensor…

Medical Physics · Physics 2023-06-19 Rafael Neto Henriques1 , Richard Henson , Cam-CAN , Marta Morgado Correia

Diabetic Foot Ulcer (DFU) is a serious skin wound requiring specialized care. However, real DFU datasets are limited, hindering clinical training and research activities. In recent years, generative adversarial networks and diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Reza Basiri , Karim Manji , Francois Harton , Alisha Poonja , Milos R. Popovic , Shehroz S. Khan

Diffusion Weighted Imaging (DWI) is an advanced imaging technique commonly used in neuroscience and neurological clinical research through a Diffusion Tensor Imaging (DTI) model. Volumetric scalar metrics including fractional anisotropy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Zihao Tang , Xinyi Wang , Lihaowen Zhu , Mariano Cabezas , Dongnan Liu , Michael Barnett , Weidong Cai , Chengyu Wang