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This paper investigates a variational approach to viscous flows with contact line dynamics based on energy-dissipation modeling. The corresponding model is reduced to a thin-film equation and its variational structure is also constructed…

Fluid Dynamics · Physics 2018-11-21 Dirk Peschka

Understanding what happens inside the rippling and dancing surface of a liquid remains one of the great challenges of fluid dynamics. Using molecular dynamics (MD) we can pick apart the interface structure and understand surface tension. In…

Computational Physics · Physics 2020-10-28 Edward R. Smith , Carlos Braga

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

We discuss a class of models for particulate gels in which the particle contacts are described by an effective interaction combining a two-body attraction and a three-body angular repulsion. Using molecular dynamics, we show how varying the…

Soft Condensed Matter · Physics 2021-08-05 Minaspi Bantawa , Wayan A. Fontaine-Seiler , Peter D. Olmsted , Emanuela Del Gado

Cytoskeletal motors known as motor proteins are molecules that drive cellular transport along several parallel cytoskeletal filaments and support many biological processes. Experimental evidences suggest that they interact with the nearest…

Statistical Mechanics · Physics 2017-11-22 Tripti Midha , A. K. Gupta

In this manuscript, we undertake an examination of a classical plasma deployed on two finite co-planar surfaces: a circular region $\Omega_{in}$ into an annular region $\Omega_{out}$ with a gap in between. It is studied both from the point…

Statistical Mechanics · Physics 2024-07-02 Robert Salazar , Cristian Cobos , Diego Jaramillo , Camilo Bayona

Fermionic Molecular Dynamics (FMD) models a system of fermions by means of many-body states which are composed of antisymmetrized products of single-particle states. These consist of one or several Gaussians localized in coordinate and…

Nuclear Theory · Physics 2007-05-23 H. Feldmeier , T. Neff , R. Roth , J. Schnack

We study the dynamics of driven polymer translocation using both molecular dynamics (MD) simulations and a theoretical model based on the non-equilibrium tension propagation on the {\it cis} side subchain. We present theoretical and…

Soft Condensed Matter · Physics 2015-06-12 Timo Ikonen , Aniket Bhattacharya , Tapio Ala-Nissila , Wokyung Sung

In the development of multiscale biological models it is crucial to establish a connection between discrete microscopic or mesoscopic stochastic models and macroscopic continuous descriptions based on cellular density. In this paper a…

Biological Physics · Physics 2009-11-13 Mark Alber , Nan Chen , Pavel M. Lushnikov , Stuart A. Newman

Large parallel gains in the development of both computational resources as well as sampling methods have now made it possible to simulate dissociation events in ligand-protein complexes with all--atom resolution. Such encouraging progress,…

Molecular Dynamics simulations are becoming a powerful tool for examining and predicting atomic and molecular processes in various environment. The present review shows how, in the fields of plasma physics, chemistry and interactions with…

Plasma Physics · Physics 2023-12-14 Pascal Brault

Nowadays, multiscale modelling is recognized as the most suitable way to study biological processes. Indeed, almost every phenomenon in nature exhibits a multiscale behaviour, i.e., it is the outcome of interactions that occur at different…

Formal Languages and Automata Theory · Computer Science 2011-08-18 Federico Buti , Massimo Callisto De Donato , Flavio Corradini , Emanuela Merelli , Luca Tesei

We propose a general multiscale approach for the mechanical behavior of three-dimensional networks of macromolecules undergoing strain-induced unfolding. Starting from a (statistically based) energetic analysis of the macromolecule…

Soft Condensed Matter · Physics 2015-06-22 Domenico De Tommasi , Giuseppe Puglisi , Giuseppe Saccomandi

The main causes of energy dissipation in micro- and nano-scale wetting are viscosity and liquid-solid friction localized in the three-phase contact line region. Theoretical models predict the contactline friction coefficient to correlate…

Fluid Dynamics · Physics 2024-02-12 Michele Pellegrino , Berk Hess

In this work we numerically investigate a new method for the characterization of growing length scales associated with spatially heterogeneous dynamics of glass-forming liquids. This approach, motivated by the formulation of the…

Disordered Systems and Neural Networks · Physics 2013-10-28 Kang Kim , Shinji Saito , Kunimasa Miyazaki , Giulio Biroli , David R. Reichman

Heterogeneous multiscale methods (HMM) combine molecular accuracy of particle-based simulations with the computational efficiency of continuum descriptions to model flow in soft matter liquids. In these schemes, molecular simulations…

Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…

Tissues and Organs · Quantitative Biology 2017-07-27 Richard J. McMurtrey

This review examines the emerging role of mechanistic mathematical models based on continuum mechanics to address current challenges in glaucoma research. At present, the advent of Artificial Intelligence and data-based models have resulted…

Tissues and Organs · Quantitative Biology 2025-10-09 Daniel Sebastia-Saez , Jinyuan Luo , Mengqi Qin , Tao Chen , Cynthia Yu-Wai-Man

The human foot serves as the critical interface between the body and environment during locomotion. Existing musculoskeletal models typically oversimplify foot-ground contact mechanics, limiting their ability to accurately simulate human…

Robotics · Computer Science 2025-08-19 Haixin Gong , Chen Zhang , Yanan Sui

Muscular dystrophy (MD) describes generalized progressive muscular weakness due to the wasting of muscle fibers. The progression of the disease is affected by known immunological and mechanical factors, and possibly other unknown…

Quantitative Methods · Quantitative Biology 2016-10-31 Amanda N. Cameron , Matthew T. Houston , Juan B. Gutierrez
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