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In this paper we aim to refine the concept of grand challenges in medical image analysis, based on statistical principles from quantitative and qualitative experimental research. We identify two types of challenges based on their…

Applications · Statistics 2019-11-21 Adriënne M. Mendrik , Stephen R. Aylward

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Matthias Eisenmann , Annika Reinke , Vivienn Weru , Minu Dietlinde Tizabi , Fabian Isensee , Tim J. Adler , Sharib Ali , Vincent Andrearczyk , Marc Aubreville , Ujjwal Baid , Spyridon Bakas , Niranjan Balu , Sophia Bano , Jorge Bernal , Sebastian Bodenstedt , Alessandro Casella , Veronika Cheplygina , Marie Daum , Marleen de Bruijne , Adrien Depeursinge , Reuben Dorent , Jan Egger , David G. Ellis , Sandy Engelhardt , Melanie Ganz , Noha Ghatwary , Gabriel Girard , Patrick Godau , Anubha Gupta , Lasse Hansen , Kanako Harada , Mattias Heinrich , Nicholas Heller , Alessa Hering , Arnaud Huaulmé , Pierre Jannin , Ali Emre Kavur , Oldřich Kodym , Michal Kozubek , Jianning Li , Hongwei Li , Jun Ma , Carlos Martín-Isla , Bjoern Menze , Alison Noble , Valentin Oreiller , Nicolas Padoy , Sarthak Pati , Kelly Payette , Tim Rädsch , Jonathan Rafael-Patiño , Vivek Singh Bawa , Stefanie Speidel , Carole H. Sudre , Kimberlin van Wijnen , Martin Wagner , Donglai Wei , Amine Yamlahi , Moi Hoon Yap , Chun Yuan , Maximilian Zenk , Aneeq Zia , David Zimmerer , Dogu Baran Aydogan , Binod Bhattarai , Louise Bloch , Raphael Brüngel , Jihoon Cho , Chanyeol Choi , Qi Dou , Ivan Ezhov , Christoph M. Friedrich , Clifton Fuller , Rebati Raman Gaire , Adrian Galdran , Álvaro García Faura , Maria Grammatikopoulou , SeulGi Hong , Mostafa Jahanifar , Ikbeom Jang , Abdolrahim Kadkhodamohammadi , Inha Kang , Florian Kofler , Satoshi Kondo , Hugo Kuijf , Mingxing Li , Minh Huan Luu , Tomaž Martinčič , Pedro Morais , Mohamed A. Naser , Bruno Oliveira , David Owen , Subeen Pang , Jinah Park , Sung-Hong Park , Szymon Płotka , Elodie Puybareau , Nasir Rajpoot , Kanghyun Ryu , Numan Saeed , Adam Shephard , Pengcheng Shi , Dejan Štepec , Ronast Subedi , Guillaume Tochon , Helena R. Torres , Helene Urien , João L. Vilaça , Kareem Abdul Wahid , Haojie Wang , Jiacheng Wang , Liansheng Wang , Xiyue Wang , Benedikt Wiestler , Marek Wodzinski , Fangfang Xia , Juanying Xie , Zhiwei Xiong , Sen Yang , Yanwu Yang , Zixuan Zhao , Klaus Maier-Hein , Paul F. Jäger , Annette Kopp-Schneider , Lena Maier-Hein

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Matthias Eisenmann , Annika Reinke , Vivienn Weru , Minu Dietlinde Tizabi , Fabian Isensee , Tim J. Adler , Patrick Godau , Veronika Cheplygina , Michal Kozubek , Sharib Ali , Anubha Gupta , Jan Kybic , Alison Noble , Carlos Ortiz de Solórzano , Samiksha Pachade , Caroline Petitjean , Daniel Sage , Donglai Wei , Elizabeth Wilden , Deepak Alapatt , Vincent Andrearczyk , Ujjwal Baid , Spyridon Bakas , Niranjan Balu , Sophia Bano , Vivek Singh Bawa , Jorge Bernal , Sebastian Bodenstedt , Alessandro Casella , Jinwook Choi , Olivier Commowick , Marie Daum , Adrien Depeursinge , Reuben Dorent , Jan Egger , Hannah Eichhorn , Sandy Engelhardt , Melanie Ganz , Gabriel Girard , Lasse Hansen , Mattias Heinrich , Nicholas Heller , Alessa Hering , Arnaud Huaulmé , Hyunjeong Kim , Bennett Landman , Hongwei Bran Li , Jianning Li , Jun Ma , Anne Martel , Carlos Martín-Isla , Bjoern Menze , Chinedu Innocent Nwoye , Valentin Oreiller , Nicolas Padoy , Sarthak Pati , Kelly Payette , Carole Sudre , Kimberlin van Wijnen , Armine Vardazaryan , Tom Vercauteren , Martin Wagner , Chuanbo Wang , Moi Hoon Yap , Zeyun Yu , Chun Yuan , Maximilian Zenk , Aneeq Zia , David Zimmerer , Rina Bao , Chanyeol Choi , Andrew Cohen , Oleh Dzyubachyk , Adrian Galdran , Tianyuan Gan , Tianqi Guo , Pradyumna Gupta , Mahmood Haithami , Edward Ho , Ikbeom Jang , Zhili Li , Zhengbo Luo , Filip Lux , Sokratis Makrogiannis , Dominik Müller , Young-tack Oh , Subeen Pang , Constantin Pape , Gorkem Polat , Charlotte Rosalie Reed , Kanghyun Ryu , Tim Scherr , Vajira Thambawita , Haoyu Wang , Xinliang Wang , Kele Xu , Hung Yeh , Doyeob Yeo , Yixuan Yuan , Yan Zeng , Xin Zhao , Julian Abbing , Jannes Adam , Nagesh Adluru , Niklas Agethen , Salman Ahmed , Yasmina Al Khalil , Mireia Alenyà , Esa Alhoniemi , Chengyang An , Talha Anwar , Tewodros Weldebirhan Arega , Netanell Avisdris , Dogu Baran Aydogan , Yingbin Bai , Maria Baldeon Calisto , Berke Doga Basaran , Marcel Beetz , Cheng Bian , Hao Bian , Kevin Blansit , Louise Bloch , Robert Bohnsack , Sara Bosticardo , Jack Breen , Mikael Brudfors , Raphael Brüngel , Mariano Cabezas , Alberto Cacciola , Zhiwei Chen , Yucong Chen , Daniel Tianming Chen , Minjeong Cho , Min-Kook Choi , Chuantao Xie Chuantao Xie , Dana Cobzas , Julien Cohen-Adad , Jorge Corral Acero , Sujit Kumar Das , Marcela de Oliveira , Hanqiu Deng , Guiming Dong , Lars Doorenbos , Cory Efird , Sergio Escalera , Di Fan , Mehdi Fatan Serj , Alexandre Fenneteau , Lucas Fidon , Patryk Filipiak , René Finzel , Nuno R. Freitas , Christoph M. Friedrich , Mitchell Fulton , Finn Gaida , Francesco Galati , Christoforos Galazis , Chang Hee Gan , Zheyao Gao , Shengbo Gao , Matej Gazda , Beerend Gerats , Neil Getty , Adam Gibicar , Ryan Gifford , Sajan Gohil , Maria Grammatikopoulou , Daniel Grzech , Orhun Güley , Timo Günnemann , Chunxu Guo , Sylvain Guy , Heonjin Ha , Luyi Han , Il Song Han , Ali Hatamizadeh , Tian He , Jimin Heo , Sebastian Hitziger , SeulGi Hong , SeungBum Hong , Rian Huang , Ziyan Huang , Markus Huellebrand , Stephan Huschauer , Mustaffa Hussain , Tomoo Inubushi , Ece Isik Polat , Mojtaba Jafaritadi , SeongHun Jeong , Bailiang Jian , Yuanhong Jiang , Zhifan Jiang , Yueming Jin , Smriti Joshi , Abdolrahim Kadkhodamohammadi , Reda Abdellah Kamraoui , Inha Kang , Junghwa Kang , Davood Karimi , April Khademi , Muhammad Irfan Khan , Suleiman A. Khan , Rishab Khantwal , Kwang-Ju Kim , Timothy Kline , Satoshi Kondo , Elina Kontio , Adrian Krenzer , Artem Kroviakov , Hugo Kuijf , Satyadwyoom Kumar , Francesco La Rosa , Abhi Lad , Doohee Lee , Minho Lee , Chiara Lena , Hao Li , Ling Li , Xingyu Li , Fuyuan Liao , KuanLun Liao , Arlindo Limede Oliveira , Chaonan Lin , Shan Lin , Akis Linardos , Marius George Linguraru , Han Liu , Tao Liu , Di Liu , Yanling Liu , João Lourenço-Silva , Jingpei Lu , Jiangshan Lu , Imanol Luengo , Christina B. Lund , Huan Minh Luu , Yi Lv , Yi Lv , Uzay Macar , Leon Maechler , Sina Mansour L. , Kenji Marshall , Moona Mazher , Richard McKinley , Alfonso Medela , Felix Meissen , Mingyuan Meng , Dylan Miller , Seyed Hossein Mirjahanmardi , Arnab Mishra , Samir Mitha , Hassan Mohy-ud-Din , Tony Chi Wing Mok , Gowtham Krishnan Murugesan , Enamundram Naga Karthik , Sahil Nalawade , Jakub Nalepa , Mohamed Naser , Ramin Nateghi , Hammad Naveed , Quang-Minh Nguyen , Cuong Nguyen Quoc , Brennan Nichyporuk , Bruno Oliveira , David Owen , Jimut Bahan Pal , Junwen Pan , Wentao Pan , Winnie Pang , Bogyu Park , Vivek Pawar , Kamlesh Pawar , Michael Peven , Lena Philipp , Tomasz Pieciak , Szymon Plotka , Marcel Plutat , Fattaneh Pourakpour , Domen Preložnik , Kumaradevan Punithakumar , Abdul Qayyum , Sandro Queirós , Arman Rahmim , Salar Razavi , Jintao Ren , Mina Rezaei , Jonathan Adam Rico , ZunHyan Rieu , Markus Rink , Johannes Roth , Yusely Ruiz-Gonzalez , Numan Saeed , Anindo Saha , Mostafa Salem , Ricardo Sanchez-Matilla , Kurt Schilling , Wei Shao , Zhiqiang Shen , Ruize Shi , Pengcheng Shi , Daniel Sobotka , Théodore Soulier , Bella Specktor Fadida , Danail Stoyanov , Timothy Sum Hon Mun , Xiaowu Sun , Rong Tao , Franz Thaler , Antoine Théberge , Felix Thielke , Helena Torres , Kareem A. Wahid , Jiacheng Wang , YiFei Wang , Wei Wang , Xiong Wang , Jianhui Wen , Ning Wen , Marek Wodzinski , Ye Wu , Fangfang Xia , Tianqi Xiang , Chen Xiaofei , Lizhan Xu , Tingting Xue , Yuxuan Yang , Lin Yang , Kai Yao , Huifeng Yao , Amirsaeed Yazdani , Michael Yip , Hwanseung Yoo , Fereshteh Yousefirizi , Shunkai Yu , Lei Yu , Jonathan Zamora , Ramy Ashraf Zeineldin , Dewen Zeng , Jianpeng Zhang , Bokai Zhang , Jiapeng Zhang , Fan Zhang , Huahong Zhang , Zhongchen Zhao , Zixuan Zhao , Jiachen Zhao , Can Zhao , Qingshuo Zheng , Yuheng Zhi , Ziqi Zhou , Baosheng Zou , Klaus Maier-Hein , Paul F. Jäger , Annette Kopp-Schneider , Lena Maier-Hein

While clinical trials are the state-of-the-art methods to assess the effect of new medication in a comparative manner, benchmarking in the field of medical image analysis is performed by so-called challenges. Recently, comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Annika Reinke , Georg Grab , Lena Maier-Hein

Medical image enhancement is crucial for improving the quality and interpretability of diagnostic images, ultimately supporting early detection, accurate diagnosis, and effective treatment planning. Despite advancements in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Chun Wai Chin , Haniza Yazid , Hoi Leong Lee

Biomedical challenges have become the de facto standard for benchmarking biomedical image analysis algorithms. While the number of challenges is steadily increasing, surprisingly little effort has been invested in ensuring high quality…

Computer Vision and Pattern Recognition · Computer Science 2019-12-06 Manuel Wiesenfarth , Annika Reinke , Bennett A. Landman , Manuel Jorge Cardoso , Lena Maier-Hein , Annette Kopp-Schneider

The astounding success made by artificial intelligence (AI) in healthcare and other fields proves that AI can achieve human-like performance. However, success always comes with challenges. Deep learning algorithms are data-dependent and…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Johann Li , Guangming Zhu , Cong Hua , Mingtao Feng , BasheerBennamoun , Ping Li , Xiaoyuan Lu , Juan Song , Peiyi Shen , Xu Xu , Lin Mei , Liang Zhang , Syed Afaq Ali Shah , Mohammed Bennamoun

The number of biomedical image analysis challenges organized per year is steadily increasing. These international competitions have the purpose of benchmarking algorithms on common data sets, typically to identify the best method for a…

Over-fitting is a dreaded foe in challenge-based competitions. Because participants rely on public leaderboards to evaluate and refine their models, there is always the danger they might over-fit to the holdout data supporting the…

Medical Image Analysis is currently experiencing a paradigm shift due to Deep Learning. This technology has recently attracted so much interest of the Medical Imaging community that it led to a specialized conference in `Medical Imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-18 Fouzia Altaf , Syed M. S. Islam , Naveed Akhtar , Naeem K. Janjua

Motivation: Medical image analysis involves tasks to assist physicians in qualitative and quantitative analysis of lesions or anatomical structures, significantly improving the accuracy and reliability of diagnosis and prognosis.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Mingzhe Hu , Jiahan Zhang , Luke Matkovic , Tian Liu , Xiaofeng Yang

Challenges have become the state-of-the-art approach to benchmark image analysis algorithms in a comparative manner. While the validation on identical data sets was a great step forward, results analysis is often restricted to pure ranking…

Academic challenges comprise effective means for (i) advancing the state of the art, (ii) putting in the spotlight of a scientific community specific topics and problems, as well as (iii) closing the gap for under represented communities in…

Machine Learning · Computer Science 2023-12-04 Hugo Jair Escalante , Aleksandra Kruchinina

To address complex problems, scholars are increasingly faced with challenges of integrating diverse knowledge domains. We analyzed the evolution of this convergence paradigm in the broad ecosystem of brain science, which provides a…

Digital Libraries · Computer Science 2021-08-09 Alexander M. Petersen , Mohammed E. Ahmed , Ioannis Pavlidis

Design studies aim to create visualization solutions for real-world problems of different application domains. Recently, the emergence of large language models (LLMs) has introduced new opportunities to enhance the design study process,…

Human-Computer Interaction · Computer Science 2025-08-14 Shaolun Ruan , Rui Sheng , Xiaolin Wen , Jiachen Wang , Tianyi Zhang , Yong Wang , Tim Dwyer , Jiannan Li

Event-driven architecture has been widely adopted in the software industry, emerging as an alternative to modular development to support rapid adaptations of constantly evolving systems. However, little is known about the effects of…

Software Engineering · Computer Science 2023-08-11 Luan Lazzari , Kleinner Farias

Models that top leaderboards often perform unsatisfactorily when deployed in real world applications; this has necessitated rigorous and expensive pre-deployment model testing. A hitherto unexplored facet of model performance is: Are our…

Computation and Language · Computer Science 2021-06-11 Swaroop Mishra , Anjana Arunkumar

Benchmarking competitions are central to the development of artificial intelligence (AI) in medical imaging, defining performance standards and shaping methodological progress. However, it remains unclear whether these benchmarks provide…

Machine learning methods exploiting multi-parametric biomarkers, especially based on neuroimaging, have huge potential to improve early diagnosis of dementia and to predict which individuals are at-risk of developing dementia. To benchmark…

Machine Learning · Computer Science 2022-02-21 Esther E. Bron , Stefan Klein , Annika Reinke , Janne M. Papma , Lena Maier-Hein , Daniel C. Alexander , Neil P. Oxtoby
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