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Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Khiem Le , Zhichun Guo , Kaiwen Dong , Xiaobao Huang , Bozhao Nan , Roshni Iyer , Xiangliang Zhang , Olaf Wiest , Wei Wang , Ting Hua , Nitesh V. Chawla

Dependent Dirichlet processes (DDP) have been widely applied to model data from distributions over collections of measures which are correlated in some way. On the other hand, in recent years, increasing research efforts in machine learning…

Machine Learning · Computer Science 2021-06-17 Xiaoli Li

Document visual question answering (DocVQA) pipelines that answer questions from documents have broad applications. Existing methods focus on handling single-page documents with multi-modal language models (MLMs), or rely on text-based…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Jaemin Cho , Debanjan Mahata , Ozan Irsoy , Yujie He , Mohit Bansal

The challenge of Multimodal Deformable Image Registration (MDIR) lies in the conversion and alignment of features between images of different modalities. Generative models (GMs) cannot retain the necessary information enough from the source…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Mingrui Ma , Weijie Wang , Jie Ning , Jianfeng He , Nicu Sebe , Bruno Lepri

This paper introduces Multimodal Speculative Decoding (MSD) to accelerate Multimodal Large Language Models (MLLMs) inference. Speculative decoding has been shown to accelerate Large Language Models (LLMs) without sacrificing accuracy.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Luxi Lin , Zhihang Lin , Zhanpeng Zeng , Rongrong Ji

Many-body dissipative particle dynamics (MDPD) offers a significant speed-up in the simulation of various systems, including soft matter, in comparison with molecular dynamics (MD) simulations based on Lennard-Jones nteractions, which is…

Soft Condensed Matter · Physics 2025-06-09 Natalia Kramarz , Luís H. Carnevale , Panagiotis E. Theodorakis

This paper invites the reader to experiment with an easy-to-use MATLAB implementation of Metropolis integrators for Molecular Dynamics (MD) simulation. These integrators are analysis-based, in the sense that they can rigorously simulate…

Computational Physics · Physics 2013-09-20 Nawaf Bou-Rabee

Molecular dynamics (MD) simulations allow atomistic insights into chemical and biological processes. Accurate MD simulations require computationally demanding quantum-mechanical calculations, being practically limited to short timescales…

Systems Biology is a fundamental field and paradigm that introduces a new era in Biology. The crux of its functionality and usefulness relies on metabolic networks that model the reactions occurring inside an organism and provide the means…

Quantitative Methods · Quantitative Biology 2022-06-03 Apostolos Chalkis , Vissarion Fisikopoulos , Elias Tsigaridas , Haris Zafeiropoulos

In this paper, we propose a flexible SLAM framework, XRDSLAM. It adopts a modular code design and a multi-process running mechanism, providing highly reusable foundational modules such as unified dataset management, 3d visualization,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Xiaomeng Wang , Nan Wang , Guofeng Zhang

Shortcut engineering consists of a class of approaches to rapidly manipulate physical systems by means of specially designed external controls. In this Letter, we apply these approaches to run-and-tumble particles, which are designed to…

Statistical Mechanics · Physics 2023-04-13 Adam G. Frim , Michael R. DeWeese

Atomistic modeling of thin-film processes provides an avenue not only for discovering key chemical mechanisms of the processes but also to extract quantitative metrics on the events and reactions taking place at the gas-surface interface.…

Materials Science · Physics 2025-05-05 S. Kondati Natarajan , J. Schneider , N. Pandey , J. Wellendorff , S. Smidstrup

Molecular dynamics is the primary computational method by which modern structural biology explores macromolecule structure and function. Boltzmann generators have been proposed as an alternative to molecular dynamics, by replacing the…

Computational Physics · Physics 2025-06-23 Congzhou M. Sha , Jian Wang , Nikolay V. Dokholyan

The extraction of molecular structures and reaction data from scientific documents is challenging due to their varied, unstructured chemical formats and complex document layouts. To address this, we introduce MolMole, a vision-based deep…

Graph Machine Learning (GML) is receiving growing interest within the pharmaceutical and biotechnology industries for its ability to model biomolecular structures, the functional relationships between them, and integrate multi-omic datasets…

The Dynamic Mode Decomposition (DMD) is a tool of trade in computational data driven analysis of fluid flows. More generally, it is a computational device for Koopman spectral analysis of nonlinear dynamical systems, with a plethora of…

Numerical Analysis · Mathematics 2017-08-10 Zlatko Drmač , Igor Mezić , Ryan Mohr

Scientific diagrams are vital tools for communicating structured knowledge across disciplines. However, they are often published as static raster images, losing symbolic semantics and limiting reuse. While Multimodal Large Language Models…

Artificial Intelligence · Computer Science 2025-10-14 Zhiqing Cui , Jiahao Yuan , Hanqing Wang , Yanshu Li , Chenxu Du , Zhenglong Ding

The interaction between proteins and DNA is a key driving force in a significant number of biological processes such as transcriptional regulation, repair, recombination, splicing, and DNA modification. The identification of DNA-binding…

Quantitative Methods · Quantitative Biology 2017-05-10 Hamid Reza Hassanzadeh , Pushkar Kolhe , Charles L. Isbell , May D. Wang

All-atom and coarse-grained molecular dynamics are two widely used computational tools to study the conformational states of proteins. Yet, these two simulation methods suffer from the fact that without access to supercomputing resources,…

Quantitative Methods · Quantitative Biology 2022-06-13 Gregory Schwing , Luigi L. Palese , Ariel Fernández , Loren Schwiebert , Domenico L. Gatti

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard