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The local hydration around tetrameric Hb in its T$_0$ and R$_4$ conformational substates is analyzed based on molecular dynamics simulations. Analysis of the local hydrophobicity (LH) for all residues at the $\alpha_1 \beta_2$ and $\alpha_2…

Chemical Physics · Physics 2022-12-09 Seyedeh Maryam Salehi , Marco Pezzella , Adam Willard , Markus Meuwly , Martin Karplus

Reactions at solid-water interfaces play a foundational role in water treatment systems, catalysis, chemical separations, and in predicting chemical fate and transport in the environment. Over the last century, experimental measurements and…

Chemical Physics · Physics 2022-12-14 Anastasia G. Ilgen , Kevin Leung , Louise J. Criscenti , Jeffery A. Greathouse

An understanding of the hydrophobicity of complex heterogeneous molecular assemblies is crucial to characterize and predict interactions between biomolecules. As such, uncovering the subtleties of assembly processes hinges on an accurate…

Soft Condensed Matter · Physics 2015-02-20 Richard C. Remsing , John D. Weeks

Over times shorter than that required for relaxation of enthalpy, a liquid can exhibit striking heterogeneities. The picture of these heterogeneities is complex with transient patches of rigidity, irregular yet persistent, intersected by…

Soft Condensed Matter · Physics 2010-09-30 Peter Harrowell

Membranes are of great technological and biological as well as theoretical interest. Two main classes of membranes can be distinguished: Fluid membranes and polymerized, tethered membranes. Here, we review progress in the theoretical…

Condensed Matter · Physics 2007-05-23 Kay Joerg Wiese

Interfacial water on transition metal oxides such as TiO$_2$ has been widely studied because of their structural complexity and scientific relevance in e.g. photocatalysis and ice growth. Using ab initio molecular dynamics, we find that…

Materials Science · Physics 2021-11-02 Keyang Liu , Jianqing Guo , Weizhong Fu , Ji Chen

Swimming micro-organisms such as bacteria or spermatozoa are typically found in dense suspensions, and exhibit collective modes of locomotion qualitatively different from that displayed by isolated cells. In the dilute limit where…

Biological Physics · Physics 2010-05-02 Sebastien Michelin , Eric Lauga

Since the pioneering works of Pethig, Grant and Wuthrich on protein hydration layer, many studies have been devoted to find out if there are any general and universal characteristic features that can distinguish water molecules inside the…

Soft Condensed Matter · Physics 2017-08-09 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

Using molecular dynamics simulations we study the dynamics of a water-like TIP5P model of water in hydrophilic and hydrophobic confinement. We find that in case of extreme nanocofinement such that there is only one molecular layer of water…

Soft Condensed Matter · Physics 2010-05-14 Pradeep Kumar

Water/solid interfaces are relevant to a broad range of physicochemical phenomena and technological processes such as corrosion, lubrication, heterogeneous catalysis and electrochemistry. Although many fields have contributed to rapid…

Materials Science · Physics 2013-01-31 Javier Carrasco , Andrew Hodgson , Angelos Michaelides

In this Letter, we present a simple model of aqueous interfacial molecular structure and we use this model to isolate the effects of hydrogen bonding on the dielectric properties of the liquid water-vapor interface. By comparing this model…

Soft Condensed Matter · Physics 2018-03-26 Sucheol Shin , Adam P. Willard

1. Role of inter-domain water clusters in large-scale dynamics of proteins; 2. Description of large-scale dynamics of proteins based on generalized Stokes-Einstein and Eyring-Polany equation; 3. Dynamic model of protein-ligand complexes…

General Physics · Physics 2007-05-23 Alex Kaivarainen

Water diffusion through membrane proteins is a key aspect of cellular function. Essential processes of cellular metabolism are driven by osmotic pressure, which depends on water channels. Membrane proteins such as aquaporins (AQPs) are…

Soft Condensed Matter · Physics 2021-11-03 Miguel A. Gonzalez , Alberto Zaragoza , Charlotte I. Lynch , Mark S. P. Sansom , Chantal Valeriani

We study the structure and dynamics of the interface separating a passive fluid from a microtubule-based active fluid. Turbulent-like active flows power giant interfacial fluctuations, which exhibit pronounced asymmetry between regions of…

We perform molecular dynamics simulation of water using the TIP5P model to quantify structural order in both the first shell (defined by four nearest neighbors)and second shell (defined by twelve next-nearest neighbors) of a central water…

By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon…

Soft Condensed Matter · Physics 2018-07-04 Martin Vögele , Jürgen Köfinger , Gerhard Hummer

Although the dynamics of colloids in the vicinity of a solid interface has been widely characterized in the past, experimental studies of Brownian diffusion close to an air-water interface are rare and limited to particle-interface gap…

Soft Condensed Matter · Physics 2022-11-11 Stefano Villa , Christophe Blanc , Abdallah Daddi-Moussa-Ider , Antonio Stocco , Maurizio Nobili

In this work we investigate the Fe$_3$O$_4$(001) surface/water interface by combining several theoretical approaches, ranging from a hybrid functional method (HSE06) to density-functional tight-binding (DFTB) to molecular mechanics (MM).…

Materials Science · Physics 2021-12-07 Hongsheng Liu , Enrico Bianchetti , Paulo Siani , Cristiana Di Valentin

Cellular uptake of nanoplastics is instrumental in their environmental accumulation and transfer to humans through the food chain. Despite extensive studies using spherical plastic nanoparticles, the influence of the morphological…

Soft Condensed Matter · Physics 2023-08-29 Xin Yong , Ke Du

We investigate the effects of heterogeneous (spatially varying) activity in a hydrodynamical model for dense bacterial suspensions, confining ourselves to experimentally realizable, simple, quenched, activity patterns. We show that the…

Soft Condensed Matter · Physics 2026-05-12 Siddhartha Mukherjee , Kunal Kumar , Samriddhi Sankar Ray
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