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Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

Radiation Therapy (RT) plays a pivotal role in the treatment of cancer, offering the potential to effectively target and eliminate tumour cells while minimizing harm to surrounding healthy tissues. However, the success of RT heavily depends…

Medical Physics · Physics 2024-02-16 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Bayesian optimization (BO) has become a popular strategy for global optimization of many expensive real-world functions. Contrary to a common belief that BO is suited to optimizing black-box functions, it actually requires domain knowledge…

Machine Learning · Computer Science 2022-07-08 Zi Wang , George E. Dahl , Kevin Swersky , Chansoo Lee , Zelda Mariet , Zachary Nado , Justin Gilmer , Jasper Snoek , Zoubin Ghahramani

3D computer-assisted corrective osteotomy has become the state-of-the-art for surgical treatment of complex bone deformities. Despite available technologies, the automatic generation of clinically acceptable, ready-to-use preoperative…

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Genetic Algorithms (GAs) are known for their efficiency in solving combinatorial optimization problems, thanks to their ability to explore diverse solution spaces, handle various representations, exploit parallelism, preserve good…

Neural and Evolutionary Computing · Computer Science 2023-09-29 Majid Sohrabi , Amir M. Fathollahi-Fard , Vasilii A. Gromov

Radiology report generation aims to produce computer-aided diagnoses to alleviate the workload of radiologists and has drawn increasing attention recently. However, previous deep learning methods tend to neglect the mutual influences…

Computation and Language · Computer Science 2022-01-12 Song Wang , Liyan Tang , Mingquan Lin , George Shih , Ying Ding , Yifan Peng

The rapid advances in the field of optimization methods in many pure and applied science pose the difficulty of keeping track of the developments as well as selecting an appropriate technique that best suits the problem in-hand. From a…

Neural and Evolutionary Computing · Computer Science 2011-12-30 Loris Serafino

Modern external beam cancer radiotherapy applies prescribed radiation doses to tumor targets while minimally affecting nearby vulnerable organs-at-risk (OARs). Creating a treatment plan is difficult and time-consuming with no guarantee of…

Medical Physics · Physics 2021-07-07 Lyndon Hibbard

The method and the advantages of an evolutionary computing based approach using a steady state genetic algorithm (GA) for the parameterization of interatomic potentials for metal oxides within the shell model framework are developed and…

Materials Science · Physics 2013-06-06 Jose Solomon , Peter Chung , Deepak Srivastava , Eric Darve

Although recent years have witnessed significant advancements in medical image segmentation, the pervasive issue of domain shift among medical images from diverse centres hinders the effective deployment of pre-trained models. Many…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Ziyang Chen , Yiwen Ye , Yongsheng Pan , Yong Xia

Intensity-modulated radiation therapy (IMRT) allows for the design of customized, highly-conformal treatments for cancer patients. Creating IMRT treatment plans, however, is a mathematically complex process, which is often tackled in…

Optimization and Control · Mathematics 2022-03-18 Danielle A. Ripsman , Thomas G. Purdie , Timothy C. Y. Chan , Houra Mahmoudzadeh

Bayesian optimisation is a well-known sample-efficient method for the optimisation of expensive black-box functions. However when dealing with big search spaces the algorithm goes through several low function value regions before reaching…

Machine Learning · Computer Science 2020-03-31 Anil Ramachandran , Sunil Gupta , Santu Rana , Cheng Li , Svetha Venkatesh

This paper presents an optimization technique for the multi-pass face milling process. Genetic algorithm (GA) is used to obtain the optimum cutting parameters by minimizing the unit production cost for a given amount of material removal.…

Computational Engineering, Finance, and Science · Computer Science 2009-02-05 Sourabh Saha

Genetic algorithm (GA) is typically used to solve nonlinear model predictive control's optimization problem. However, the size of the search space in which the GA searches for the optimal control inputs is crucial for its applicability to…

Optimization and Control · Mathematics 2025-01-22 Eslam Mostafa , Hussein A. Aly , Ahmed Elliethy

In many real-world optimization problems, we have prior information about what objective function values are achievable. In this paper, we study the scenario that we have either exact knowledge of the minimum value or a, possibly inexact,…

Machine Learning · Computer Science 2025-09-26 Hanyang Wang , Juergen Branke , Matthias Poloczek

Measurement quality assurance (QA) practices play a key role in the safe use of Intensity Modulated Radiation Therapies (IMRT) for cancer treatment. These practices have reduced measurement-based IMRT QA failure below 1%. However, these…

Machine Learning · Computer Science 2025-01-16 Kevin He , David Adam , Sarah Han-Oh , Anqi Liu

Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously…

Medical Physics · Physics 2018-03-14 Daniel O'Connor , Dan Nguyen , Dan Ruan , Victoria Yu , Ke Sheng

Recent trends in self-supervised representation learning have focused on removing inductive biases from training pipelines. However, inductive biases can be useful in settings when limited data are available or provide additional insight…

Computer Vision and Pattern Recognition · Computer Science 2022-09-09 Kevin Miao , Akash Gokul , Raghav Singh , Suzanne Petryk , Joseph Gonzalez , Kurt Keutzer , Trevor Darrell , Colorado Reed

This paper proposes Genetic Algorithm with Border Trades (GAB), a novel modification of the standard genetic algorithm that enhances exploration by incorporating new chromosome patterns in the breeding process. This approach significantly…

Machine Learning · Computer Science 2025-06-27 Qingchuan Lyu