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Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

Machine Learning · Computer Science 2022-12-12 Harshit Parmar , Eric Walden

Automatic classification of diabetic retinopathy from retinal images has been widely studied using deep neural networks with impressive results. However, there is a clinical need for estimation of the uncertainty in the classifications, a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Joel Jaskari , Jaakko Sahlsten , Theodoros Damoulas , Jeremias Knoblauch , Simo Särkkä , Leo Kärkkäinen , Kustaa Hietala , Kimmo Kaski

DRDr II is a hybrid of machine learning and deep learning worlds. It builds on the successes of its antecedent, namely, DRDr, that was trained to detect, locate, and create segmentation masks for two types of lesions (exudates and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Farzan Shenavarmasouleh , Farid Ghareh Mohammadi , M. Hadi Amini , Hamid R. Arabnia

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

Diabetic retinopathy (DR) is one of the major blindness-causing diseases currently known. Automatic grading of DR using deep learning methods not only speeds up the diagnosis of the disease but also reduces the rate of misdiagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-25 Lei Shi , Bin Wang , Junxing Zhang

Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Sharath M Shankaranarayana

Diabetic Retinopathy (DR) is a common complication of diabetes and a leading cause of blindness worldwide. Early and accurate grading of its severity is crucial for disease management. Although deep learning has shown great potential for…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Haoxuan Che , Yuhan Cheng , Haibo Jin , Hao Chen

Diabetic retinopathy (DR) is one of the most common eye conditions among diabetic patients. However, vision loss occurs primarily in the late stages of DR, and the symptoms of visual impairment, ranging from mild to severe, can vary…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Peisheng Qian , Ziyuan Zhao , Cong Chen , Zeng Zeng , Xiaoli Li

Although deep learning based diabetic retinopathy (DR) classification methods typically benefit from well-designed architectures of convolutional neural networks, the training setting also has a non-negligible impact on the prediction…

Image and Video Processing · Electrical Eng. & Systems 2022-10-19 Yijin Huang , Li Lin , Pujin Cheng , Junyan Lyu , Roger Tam , Xiaoying Tang

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Deep learning techniques are recently being used in fundus image analysis and diabetic retinopathy detection. Microaneurysms are an important indicator of diabetic retinopathy progression. We introduce a two-stage deep learning approach for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-25 Mhd Hasan Sarhan , Shadi Albarqouni , Mehmet Yigitsoy , Nassir Navab , Abouzar Eslami

Diabetic retinopathy (DR) is a leading cause of preventable blindness, and automated fundus image grading can play an important role in large-scale screening. In this work, we investigate three CLIP-based approaches for five-class DR…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Sungjun Cho

Automatic evaluation of the retinal fundus image is emerging as one of the most important tools for early detection and treatment of progressive eye diseases like Glaucoma. Glaucoma results to a progressive degeneration of vision and is…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Sneha Dasgupta , Rishav Mukherjee , Kaushik Dutta , Anindya Sen

Eye is the essential sense organ for vision function. Due to the fact that certain eye disorders might result in vision loss, it is essential to diagnose and treat eye diseases early on. By identifying common eye illnesses and performing an…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Tareq Babaqi , Manar Jaradat , Ayse Erdem Yildirim , Saif H. Al-Nimer , Daehan Won

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Xi Luo , Shixin Xu , Ying Xie , JianZhong Hu , Yuwei He , Yuhui Deng , Huaxiong Huang

Deep learning-based models are developed to automatically detect if a retina image is `referable' in diabetic retinopathy (DR) screening. However, their classification accuracy degrades as the input images distributionally shift from their…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Jay Nandy , Wynne Hsu , Mong Li Lee

This paper proposes the importance of age and gender information in the diagnosis of diabetic retinopathy. We utilized Deep Residual Neural Networks (ResNet) and Densely Connected Convolutional Networks (DenseNet), which are proven…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Long Bai , Sihang Chen , Mingyang Gao , Leila Abdelrahman , Manal Al Ghamdi , Mohamed Abdel-Mottaleb

Diabetic Retinopathy (DR) is a major cause of global blindness, necessitating early and accurate diagnosis. While deep learning models have shown promise in DR detection, their black-box nature often hinders clinical adoption due to a lack…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Masato Ito , Kaito Tanaka , Keisuke Matsuda , Aya Nakayama

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han