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Species tree reconstruction from genomic data is increasingly performed using methods that account for sources of gene tree discordance such as incomplete lineage sorting. One popular method for reconstructing species trees from unrooted…

Populations and Evolution · Quantitative Biology 2017-12-06 Shubhanshu Shekhar , Sebastien Roch , Siavash Mirarab

Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the previous step. However, uncertainty in the…

Applications · Statistics 2014-11-25 Heejung Shim , Bret Larget

We propose a novel method for the inference of phylogenetic trees that utilises point configurations on hyperbolic space as its optimisation landscape. Each taxon corresponds to a point of the point configuration, while the evolutionary…

Machine Learning · Computer Science 2021-06-07 Benjamin Wilson

Finding the length of the longest increasing subsequence (LIS) is a classic algorithmic problem. Let $n$ denote the size of the array. Simple $O(n\log n)$ algorithms are known for this problem. We develop a polylogarithmic time randomized…

Data Structures and Algorithms · Computer Science 2013-08-06 M. Saks , C. Seshadhri

Phylogenetic networks allow modeling reticulate evolution, capturing events such as hybridization and horizontal gene transfer. A fundamental computational problem in this context is the Tree Containment problem, which asks whether a given…

Data Structures and Algorithms · Computer Science 2026-03-13 Sebastian Bruchhold , Mathias Weller

This paper deals with gene networks whose dynamics is assumed to be generated by a continuous-time, linear, time invariant, finite dimensional system (LTI) at steady state. In particular, we deal with the problem of network reconstruction…

Quantitative Methods · Quantitative Biology 2007-05-23 Lorenzo Farina , Ilaria Mogno

The tree inclusion problem is, given two node-labeled trees $P$ and $T$ (the ``pattern tree'' and the ``target tree''), to locate every minimal subtree in $T$ (if any) that can be obtained by applying a sequence of node insertion operations…

Data Structures and Algorithms · Computer Science 2021-06-16 Tatsuya Akutsu , Jesper Jansson , Ruiming Li , Atsuhiro Takasu , Takeyuki Tamura

Recent advances in DNA sequencing technology and DNA storage systems have rekindled the interest in deletion channels. Multiple recent works have looked at variants of sequence reconstruction over a single and over multiple deletion…

Information Theory · Computer Science 2020-06-01 Sundara Rajan Srinivasavaradhan , Michelle Du , Suhas Diggavi , Christina Fragouli

In this paper, we study the parallel query complexity of reconstructing biological and digital phylogenetic trees from simple queries involving their nodes. This is motivated from computational biology, data protection, and computer…

Data Structures and Algorithms · Computer Science 2020-09-10 Ramtin Afshar , Michael T. Goodrich , Pedro Matias , Martha C. Osegueda

An important problem in evolutionary biology is to reconstruct the evolutionary history of a set $X$ of species. This history is often represented as a phylogenetic network, that is, a connected graph with leaves labelled by elements in $X$…

Combinatorics · Mathematics 2017-02-01 Leo van Iersel , Vincent Moulton

In computational phylogenetics, the problem of constructing a supertree of a given set of rooted input trees can be formalized in different ways, to cope with contradictory information in the input. We consider the Minimum Flip Supertree…

Data Structures and Algorithms · Computer Science 2011-04-25 Sebastian Böcker

Phylogenetic tree inference using deep DNA sequencing is reshaping our understanding of rapidly evolving systems, such as the within-host battle between viruses and the immune system. Densely sampled phylogenetic trees can contain special…

Populations and Evolution · Quantitative Biology 2020-06-03 Cheng Zhang , Vu Dinh , Frederick A. Matsen

The ancestral maximum-likelihood and phylogeography problems are two fundamental problems involving evolutionary studies. The ancestral maximum-likelihood problem involves identifying a rooted tree alongside internal node sequences that…

Data Structures and Algorithms · Computer Science 2023-08-15 Mohammad-Hadi Foroughmand-Araabi , Sama Goliaei , Kasra Alishahi

Longest Increasing Subsequence (LIS) is a fundamental statistic of a sequence, and has been studied for decades. While the LIS of a sequence of length $n$ can be computed exactly in time $O(n\log n)$, the complexity of estimating the…

Data Structures and Algorithms · Computer Science 2022-11-02 Alexandr Andoni , Negev Shekel Nosatzki , Sandip Sinha , Clifford Stein

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

The log-det distance between two aligned DNA sequences was introduced as a tool for statistically consistent inference of a gene tree under simple non-mixture models of sequence evolution. Here we prove that the log-det distance, coupled…

Populations and Evolution · Quantitative Biology 2018-06-14 Elizabeth S. Allman , Colby Long , John A. Rhodes

Existing parallel algorithms for wavelet tree construction have a work complexity of $O(n\log\sigma)$. This paper presents parallel algorithms for the problem with improved work complexity. Our first algorithm is based on parallel integer…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-17 Julian Shun

Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. In the case of bacteria, distances can be estimated using a range of different evolutionary models, from single nucleotide…

Populations and Evolution · Quantitative Biology 2017-04-17 Stuart Serdoz , Attila Egri-Nagy , Jeremy Sumner , Barbara R. Holland , Peter D. Jarvis , Mark M. Tanaka , Andrew R. Francis

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

Populations and Evolution · Quantitative Biology 2013-07-24 Ruth Davidson , Seth Sullivant

Orchard and tree-child networks share an important property with phylogenetic trees: they can be completely reduced to a single node by iteratively deleting cherries and reticulated cherries. As it is the case with phylogenetic trees, the…

Populations and Evolution · Quantitative Biology 2024-03-22 Tomás M. Coronado , Joan Carles Pons , Gabriel Riera