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Design of experiments and model selection, though essential steps in data science, are usually viewed as unrelated processes in the study and analysis of biological networks. Not accounting for their inter-relatedness has the potential to…

Algebraic Geometry · Mathematics 2024-11-19 Anyu Zhang , Jingzhen Hu , Qingzhong Liang , Elena S. Dimitrova , Brandilyn Stigler

In the field of algebraic systems biology, the number of minimal polynomial models constructed using discretized data from an underlying system is related to the number of distinct reduced Gr\"obner bases for the ideal of the data points.…

Algebraic Geometry · Mathematics 2024-11-19 Anyu Zhang , Brandilyn Stigler

A strong link between information geometry and algebraic statistics is made by investigating statistical manifolds which are algebraic varieties. In particular it it shown how first and second order efficient estimators can be constructed,…

Statistics Theory · Mathematics 2014-01-13 Kei Kobayashi , Henry P. Wynn

As datasets used in scientific applications become more complex, studying the geometry and topology of data has become an increasingly prevalent part of the data analysis process. This can be seen for example with the growing interest in…

Algebraic Geometry · Mathematics 2024-03-22 Ezzeddine El Sai , Parker Gara , Markus J. Pflaum

Differential algebra approaches to structural identifiability analysis of a dynamic system model in many instances heavily depend upon Ritt's pseudodivision at an early step in analysis. The pseudodivision algorithm is used to find the…

Algebraic Geometry · Mathematics 2012-03-21 Nicolette Meshkat , Chris Anderson , Joseph J. DiStefano

We investigate how classifiers for Boolean networks (BNs) can be constructed and modified under constraints. A typical constraint is to observe only states in attractors or even more specifically steady states of BNs. Steady states of BNs…

Commutative Algebra · Mathematics 2021-08-20 Robert Schwieger , Matías R. Bender , Heike Siebert , Christian Haase

Algebraic statistics is a recently evolving field, where one would treat statistical models as algebraic objects and thereby use tools from computational commutative algebra and algebraic geometry in the analysis and computation of…

Information Theory · Computer Science 2007-07-13 Ambedkar Dukkipati

Recent studies show that transformer-based architectures emulate gradient descent during a forward pass, contributing to in-context learning capabilities - an ability where the model adapts to new tasks based on a sequence of prompt…

Statistics Theory · Mathematics 2024-05-13 Karthik Duraisamy

Experimental sciences have come to depend heavily on our ability to organize and interpret high-dimensional datasets. Natural laws, conservation principles, and inter-dependencies among observed variables yield geometric structure, with…

Quantum Physics · Physics 2022-12-15 Akshat Kumar , Mohan Sarovar

It is known that statistical model selection as well as identification of dynamical equations from available data are both very challenging tasks. Physical systems behave according to their underlying dynamical equations which, in turn, can…

Mathematical Physics · Physics 2017-10-11 Sean Alan Ali , Carlo Cafaro

In many data science applications, the objective is to extract appropriately-ordered smooth low-dimensional data patterns from high-dimensional data sets. This is challenging since common sorting algorithms are primarily aiming at finding…

Machine Learning · Computer Science 2024-10-30 Illia Horenko , Lukas Pospisil

Physical systems behave according to their underlying dynamical equations which, in turn, can be identified from experimental data. Explaining data requires selecting mathematical models that best capture the data regularities. Identifying…

Data Analysis, Statistics and Probability · Physics 2014-03-18 Carlo Cafaro

We develop algebraic tools for statistical inference from samples of rotation matrices. This rests on the theory of D-modules in algebraic analysis. Noncommutative Gr\"obner bases are used to design numerical algorithms for maximum…

Statistics Theory · Mathematics 2020-12-30 Michael F. Adamer , András C. Lőrincz , Anna-Laura Sattelberger , Bernd Sturmfels

While existing mathematical descriptions can accurately account for phenomena at microscopic scales (e.g. molecular dynamics), these are often high-dimensional, stochastic and their applicability over macroscopic time scales of physical…

Machine Learning · Statistics 2016-09-08 P. S. Koutsourelakis , Elias Bilionis

Recognition of evolutionary units (species, populations) requires integrating several kinds of data such as genetic or phenotypic markers or spatial information, in order to get a comprehensive view concerning the differentiation of the…

Populations and Evolution · Quantitative Biology 2011-12-22 Gilles Guillot , Sabrina Renaud , Ronan Ledevin , Joahn Michaux , Julien Claude

Categorical data are present in key areas such as health or supply chain, and this data require specific treatment. In order to apply recent machine learning models on such data, encoding is needed. In order to build interpretable models,…

Machine Learning · Computer Science 2023-04-19 Paul Peseux , Maxime Berar , Thierry Paquet , Victor Nicollet

Accurate model selection is a fundamental requirement for statistical analysis. In many real-world applications of graphical modelling, correct model structure identification is the ultimate objective. Standard model validation procedures…

Machine Learning · Statistics 2019-08-28 Robert O'Shea

Single-cell data analysis seeks to characterize cellular heterogeneity based on high-dimensional gene expression profiles. Conventional approaches represent each cell as a vector in Euclidean space, which limits their ability to capture…

Machine Learning · Computer Science 2025-11-18 Xiang Xiang Wang , Sean Cottrell , Guo-Wei Wei

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

Machine Learning · Statistics 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

A rigorous methodology is proposed to study cell division data consisting in several observed genealogical trees of possibly different shapes. The procedure takes into account missing observations, data from different trees, as well as the…

Applications · Statistics 2013-04-15 Benoîte de Saporta , Anne Gégout Petit , Laurence Marsalle
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