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Systemic drug administration often causes off-target effects limiting the efficacy of advanced therapies. Targeted drug delivery approaches increase local drug concentrations at the diseased site while minimizing systemic drug exposure. We…

Molecular communication (MC) is a model of information transmission where the signal is transmitted by information-carrying molecules through their physical transport from a transmitter to a receiver through a communication channel. Prior…

Statistical Mechanics · Physics 2026-05-05 Phanindra Dewan , Sumantra Sarkar

In this paper, we design a drug release mechanism for dynamic time division multiple access (TDMA)-based molecular communication via diffusion (MCvD). In the proposed scheme, the communication frame is divided into several time slots over…

Signal Processing · Electrical Eng. & Systems 2019-09-02 Hamid Khoshfekr Rudsari , Nader Mokari , Mohammad Reza Javan , Eduard A. Jorswieck , Mahdi Orooji

Molecular communications (MC), where molecules are used to encode, transmit, and receive information, is a promising means of enabling the coordination of nanoscale devices. The paradigm has been extensively studied from various aspects,…

Emerging Technologies · Computer Science 2016-03-29 Murat Kuscu , Ozgur B. Akan

Local drug delivery has received much recognition in recent years, yet it is still unpredictable how drug efficacy depends on physicochemical properties and delivery kinetics. The purpose of the current study is to provide a useful…

Dynamical Systems · Mathematics 2016-01-26 Koyel Chakravarty , D C Dalal

Drug delivery devices based on nanocomposite membranes containing thermoresponsive nanogels and superparamagnetic nanoparticles have been demonstrated to provide reversible, on-off drug release upon application (and removal) of an…

In this work we investigate the use of nanoporous carrier as drug delivery systems for hydrophobic molecules. By studying a model system made of porous silicon loaded with beta-carotene, we unveil a fundamental limitation of these carriers…

Soft Condensed Matter · Physics 2020-01-23 Chiara Piotto , Paolo Bettotti

Thermoresponsive hydrogels have been studied intensively for creating smart drug carriers and controlled drug delivery. Understanding the drug release kinetics and corresponding transport mechanisms of nanoparticles (NPs) in a…

Soft Condensed Matter · Physics 2020-05-12 Yi Wang , Zhen Li , Jie Ouyang , George Em Karniadakis

On-demand controlled drug delivery is essential for the treatment of a wide range of chronic diseases. As the drug is released at the time when required, its efficacy is boosted and the side effects are minimized. However, so far, drug…

Robotics · Computer Science 2024-03-06 Yangchao Zhou , Moonkwang Jeong , Meng Zhang , Xuexin Duan , Tian Qiu

Molecular communication (MC) is a bio-inspired communication method based on the exchange of molecules for information transfer among nanoscale devices. Although MC has been extensively studied from various aspects, limitations imposed by…

Emerging Technologies · Computer Science 2016-07-29 Murat Kuscu , Ozgur B. Akan

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, highlighting the urgent need for advanced therapeutic strategies. Nanoparticle-based drug delivery systems have emerged as a promising approach to…

Inspired by Nature, molecular communications (MC), i.e., use of molecules to encode, transmit and receive information, stands as the most promising communication paradigm to realize nanonetworks. Even though there has been extensive…

Emerging Technologies · Computer Science 2019-06-04 Murat Kuscu , Ergin Dinc , Bilgesu A. Bilgin , Hamideh Ramezani , Ozgur B. Akan

This paper studies the problem of receiver modeling in molecular communication systems. We consider the diffusive molecular communication channel between a transmitter nano-machine and a receiver nano-machine in a fluid environment. The…

Emerging Technologies · Computer Science 2016-10-04 Arman Ahmadzadeh , Hamidreza Arjmandi , Andreas Burkovski , Robert Schober

In this paper, a diffusion-based molecular communication channel is modeled in presence of a probabilistic absorber. The probabilistic absorber is an absorber which absorbs molecules upon collision with probability q. With random walk…

Emerging Technologies · Computer Science 2019-09-19 S Salehi , NS Moayedian , E Alarcón

In this paper, we consider a multi-hop molecular communication network consisting of one nanotransmitter, one nanoreceiver, and multiple nanotransceivers acting as relays. We consider three different relaying schemes to improve the range of…

Information Theory · Computer Science 2016-11-17 Arman Ahmadzadeh , Adam Noel , Robert Schober

Molecular communication (MC) is a kind of communication technology based on biochemical molecules for internet of bio-nano things, in which the biochemical molecule is used as the information carrier for the interconnection of nano-devices.…

Information Theory · Computer Science 2017-09-15 Jiaxing Wang , Bonan Yin , Mugen Peng

Molecular communication (MC) is a bio-inspired method of transmitting information using biochemical signals, promising for novel medical, agricultural, and environmental applications at the intersection of bio-, nano-, and communication…

Emerging Technologies · Computer Science 2024-08-20 Eren Akyol , Ahmet Baha Ozturk , Iman Mokari Bolhassan , Murat Kuscu

Predicting the release performance of a drug delivery device is an important challenge in pharmaceutics and biomedical science. In this paper, we consider a multi-layer diffusion model of drug release from a composite spherical microcapsule…

Medical Physics · Physics 2019-01-25 Elliot J. Carr , Giuseppe Pontrelli

This paper studies the impact of a transmitter's molecule generation process on the capacity of a concentration based Molecular Communication (MC) system. Constraints caused by the molecule generation process affect the availability of the…

Information Theory · Computer Science 2018-02-27 Hamid G. Bafghi , Amin Gohari , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari

The nature of molecular transmitter imposes some limitations on the molecule production process and its storage. As the molecules act the role of the information carriers, the limitations affect the transmission process and the system…

Information Theory · Computer Science 2019-07-23 Ladan Khaloopour , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari