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This work proposes a gradient-based method to design bone implants using triply-periodic minimal surfaces (TPMS) of spatially varying thickness to maximize bone in-growth. Bone growth into the implant is estimated using a finite element…
Many critical infrastructure systems have network structure and are under stress. Despite their national importance, the complexity of large-scale transport networks means we do not fully understand their vulnerabilities to cascade…
Complexity and heterogeneity of bone tissue require a multiscale modelling to understand their mechanical behaviour and their remodelling mechanism. Human cortical bone structure consists of six structural scale levels which are the…
Osteoporosis can be identified by looking at 2D x-ray images of the bone. The high degree of similarity between images of a healthy bone and a diseased one makes classification a challenge. A good bone texture characterization technique is…
The importance of studying properties of networks is manifest in diverse fields ranging from biology, engineering, physics, chemistry, neuroscience, and medicine. The functionality of networks with regard to performance, throughput,…
The relationship between knee osteoarthritis progression and changes in tibial bone structure has long been recognized and various texture descriptors have been proposed to detect early osteoarthritis (OA) from radiographs. This work aims…
Much effort has been devoted to understand how temporal network features and the choice of the source node affect the prevalence of a diffusion process. In this work, we addressed the further question: node pairs with what kind of local and…
Nervous systems are characterized by neurons displaying a diversity of morphological shapes. Traditionally, different shapes have been qualitatively described based on visual inspection and quantitatively described based on morphometric…
We consider a class of random, weighted networks, obtained through a redefinition of patterns in an Hopfield-like model and, by performing percolation processes, we get information about topology and resilience properties of the networks…
Understanding the relationship between the microscopic structure and topology of a material and its macroscopic properties is a fundamental challenge across a wide range of systems. Here, we investigate the viscoelasticity of DNA nanostar…
Networks describe a variety of interacting complex systems in social science, biology and information technology. Usually the nodes of real networks are identified not only by their connections but also by some other characteristics.…
During the last decade, network approaches became a powerful tool to describe protein structure and dynamics. Here we review the links between disordered proteins and the associated networks, and describe the consequences of local,…
We review the main tools which allow for the statistical characterization of weighted networks. We then present two case studies, the airline connection network and the scientific collaboration network, which are representative of critical…
We present a learning algorithm that uses bone-driven motion networks to predict the deformation of loose-fitting garment meshes at interactive rates. Given a garment, we generate a simulation database and extract virtual bones from…
Transport networks are crucial to the functioning of natural and technological systems. Nature features transport networks that are adaptive over a vast range of parameters, thus providing an impressive level of robustness in supply.…
Metabolic networks are probably among the most challenging and important biological networks. Their study provides insight into how biological pathways work and how robust a specific organism is against an environment or therapy. Here we…
Knowing the structure of an offline social network facilitates a variety of analyses, including studying the rate at which infectious diseases may spread and identifying a subset of actors to immunize in order to reduce, as much as…
Additive manufacturing (AM) of titanium (Ti) and Ti-6Al-4V lattices has been proposed for bone implants and augmentation devices. Ti and Ti-6Al-4V have favourable biocompatibility, corrosion resistance and fatigue strength for bone…
We study the micromechanics of collagen-I gel with the goal of bridging the gap between theory and experiment in the study of biopolymer networks. Three-dimensional images of fluorescently labeled collagen are obtained by confocal…
Virtual networks are an innovative abstraction that extends cloud computing concepts to the network: by supporting bandwidth reservations between compute nodes (e.g., virtual machines), virtual networks can provide a predictable performance…