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Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby

Photoacoustic tomography (PAT) is a novel and promising technology in hybrid medical imaging that involves generating acoustic waves in the object of interest by stimulating electromagnetic energy. The acoustic wave is measured outside the…

Numerical Analysis · Mathematics 2022-08-24 Minam Moon , Injo Hur , Sunghwan Moon

Photoacoustic tomography (PAT) is a non-invasive imaging modality that requires recovering the initial data of the wave equation from certain measurements of the solution outside the object. In the standard PAT measurement setup, the used…

Analysis of PDEs · Mathematics 2021-12-07 Linh V. Nguyen , Markus Haltmeier , Richard Kowar , Ngoc Do

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Photoacoustic computed tomography (PACT) is an emerging imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the photoacoustically induced initial pressure distribution within tissue. The…

In this paper, we present a powerful method (Atomistic Green's Function, AGF) for calculating the effective Hamiltonian of acoustic and elastic wave-scatterers. The ability to calculate the effective Hamiltonian allows for the study of…

Applied Physics · Physics 2024-04-30 Hossein Khodavirdi , Zhun-Yong Ong , Ankit Srivastava

Standard photoacoustic tomography (PAT) provides data that consist of time-dependent signals governed by the wave equation, which are measured on an observation surface. In contrast, the measured data from the recently invented full-field…

Numerical Analysis · Mathematics 2024-06-10 Ngoc Do , Markus Haltmeier , Richard Kowar , Linh V. Nguyen , Robert Nuster

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

The photoacoustic tomography (PAT) is a hybrid modality that combines the optics and acoustics to obtain high resolution and high contrast imaging of heterogeneous media. In this work, our objective is to study the inverse problem in the…

Numerical Analysis · Mathematics 2021-05-26 Hongkai Zhao , Yimin Zhong

Quantitative photo-acoustic tomography (QPAT) seeks to reconstruct a distribution of optical attenuation coefficients inside a sample from a set of time series of pressure data that is measured outside the sample. The associated inverse…

Optimization and Control · Mathematics 2019-09-04 Ashkan Javaherian , Sean Holman

The Hamiltonian coupled-mode theory (HCMT), recently derived by Athanassoulis and Papoutsellis [1], provides an efficient new approach for solving fully nonlinear water-wave problems over arbitrary bathymetry. In HCMT, heavy use is made of…

Computational Physics · Physics 2018-02-23 Theodosios K. Papathanasiou , Christos E. Papoutsellis , Gerassimos A. Athanassoulis

We present an optimization framework for photo-acoustic tomography of brain based on a system of coupled equations that describe the propagation of sound waves in linear isotropic inhomogeneous and lossy elastic media with the absorption…

Numerical Analysis · Mathematics 2018-07-04 Ashkan Javaherian , Sean Holman

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

In this article, we study several reconstruction methods for the inverse source problem of photoacoustic tomography (PAT) with spatially variable sound speed and damping. The backbone of these methods is the adjoint operators, which we…

Analysis of PDEs · Mathematics 2018-08-21 Linh V. Nguyen , Markus Haltmeier

In this paper, we perform non-linear minimization using the Hybridizable Discontinuous Galerkin method (HDG) for the discretization of the forward problem, and implement the adjoint-state method for the computation of the functional…

Analysis of PDEs · Mathematics 2020-09-10 Florian Faucher , Otmar Scherzer

Efficient numerical solution of the acoustic Helmholtz equation in heterogeneous media remains challenging, particularly for large-scale problems with spatially-varying density - a limitation that restricts applications in biomedical…

Computational Physics · Physics 2025-07-23 Antonio Stanziola , Simon R. Arridge , Bradley E. Treeby , Benjamin T. Cox

Quantitative Photoacoustic tomography (QPAT) is an emerging medical imaging modality which offers the possibility of combining the high resolution of the acoustic waves and large contrast of optical waves by quantifying the molecular…

Numerical Analysis · Mathematics 2014-10-30 Adriano De Cezaro , Fabiana Travessini De Cezaro

The inverse source problem arising in photoacoustic tomography and in several other coupled-physics modalities is frequently solved by iterative algorithms. Such algorithms are based on the minimization of a certain cost functional. In…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Andreas Hauptmann , Leonid Kunyansky , Jenni Poimala

This is the full and extended version of the brief note arXiv:1908.00938. A nontrivially solvable 4-dimensional Hamiltonian system is applied to the problem of wave fronts and to the asymptotic theory of partial differential equations. The…

Exactly Solvable and Integrable Systems · Physics 2021-07-15 Yu. Brezhnev , A. Tsvetkova

In this article, we are concerned with a nonlinear inverse problem with a forward operator involving an unknown function. The problem arises in diverse applications and is challenging in the presence of an unknown function, which makes it…

Numerical Analysis · Mathematics 2023-02-07 Gyeongha Hwang , Gihyeon Jeon , Sunghwan Moon
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