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Hippocampal neurons track positions of self, others, and gaze direction. However, it is unclear how their respective neural codes differ enough to avoid confusion while allowing for abstraction. We recorded from populations of hippocampal…

We posit that hippocampal place cells encode information about future locations under a transition distribution observed as an agent explores a given (physical or conceptual) space. The encoding of information about the current location,…

Machine Learning · Computer Science 2019-06-07 Mariano Tepper

While deep learning has led to remarkable advances across diverse applications, it struggles in domains where the data distribution changes over the course of learning. In stark contrast, biological neural networks continually adapt to…

Machine Learning · Computer Science 2017-06-14 Friedemann Zenke , Ben Poole , Surya Ganguli

Unlike other tissue types, like epithelial tissue, which consist of cells with a much more homogeneous structure and function, the nervous tissue spans in a complex multilayer environment whose topographical features display a large…

Biological Physics · Physics 2017-05-12 C. Simitzi , A. Ranella , E. Stratakis

In order to perform complex actions in human environments, an autonomous robot needs the ability to understand the environment, that is, to gather and maintain spatial knowledge. Topological map is commonly used for representing large…

Robotics · Computer Science 2017-07-11 Kaiyu Zheng

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites. Each stage occurs within a certain period of time depending on types of neurons and…

Neurons and Cognition · Quantitative Biology 2015-03-16 Sol Lim , Marcus Kaiser

Spiking neural networks (SNNs) offer a promising alternative to current artificial neural networks to enable low-power event-driven neuromorphic hardware. Spike-based neuromorphic applications require processing and extracting meaningful…

Neural and Evolutionary Computing · Computer Science 2019-06-24 Deboleena Roy , Priyadarshini Panda , Kaushik Roy

Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

Neurons and Cognition · Quantitative Biology 2023-12-05 Ian H. Stevenson

Spiking networks that perform probabilistic inference have been proposed both as models of cortical computation and as candidates for solving problems in machine learning. However, the evidence for spike-based computation being in any way…

Neural and Evolutionary Computing · Computer Science 2017-10-12 Luziwei Leng , Roman Martel , Oliver Breitwieser , Ilja Bytschok , Walter Senn , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…

Neurons and Cognition · Quantitative Biology 2015-09-17 James Kozloski

How does the brain predict physical outcomes while acting in the world? Machine learning world models compress visual input into latent spaces, discarding the spatial structure that characterizes sensory cortex. We propose isomorphic world…

Neurons and Cognition · Quantitative Biology 2026-02-24 Joshua Nunley

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

Neurons and Cognition · Quantitative Biology 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

The standard model of memory consolidation foresees that memories are initially recorded in the hippocampus, while features that capture higher-level generalisations of data are created in the cortex, where they are stored for a possibly…

Neurons and Cognition · Quantitative Biology 2017-06-20 Alessandro Fontana

The brain exhibits capabilities of fast incremental learning from few noisy examples, as well as the ability to associate similar memories in autonomously-created categories and to combine contextual hints with sensory perceptions. Together…

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

Small-World Networks (SWNs) represent a fundamental model for the comprehension of many complex man-made and biological networks. In the central nervous system, SWN models have been shown to fit well both anatomical and functional maps at…

Neural networks are composed of neurons and synapses, which are responsible for learning in a slow adaptive dynamical process. Here we experimentally show that neurons act like independent anisotropic multiplex hubs, which relay and mute…

Neurons and Cognition · Quantitative Biology 2017-07-21 Roni Vardi , Amir Goldental , Anton Sheinin , Shira Sardi , Ido Kanter

The space of possible behaviors complex biological systems may exhibit is unimaginably vast, and these systems often appear to be stochastic, whether due to variable noisy environmental inputs or intrinsically generated chaos. The brain is…

Neurons and Cognition · Quantitative Biology 2025-04-01 Jacob T. Crosser , Braden A. W. Brinkman