Related papers: Through synapses to spatial memory maps: a topolog…
The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…
Spatial navigation in mammals is based on building a mental representation of their environment---a cognitive map. However, both the nature of this cognitive map and its underpinning in neural structures and activity remains vague. A key…
The spiking activity of the hippocampal place cells plays a key role in producing and sustaining an internalized representation of the ambient space---a cognitive map. These cells do not only exhibit location-specific spiking during…
Spatial awareness in mammals is based on internalized representations of the environment---cognitive maps---encoded by networks of spiking neurons. Although behavioral studies suggest that these maps can remain stable for long periods, it…
Hippocampal cognitive map---a neuronal representation of the spatial environment---is broadly discussed in the computational neuroscience literature for decades. More recent studies point out that hippocampus plays a major role in producing…
It is widely accepted that the hippocampal place cells' spiking activity produces a cognitive map of space. However, many details of this representation's physiological mechanism remain unknown. For example, it is believed that the place…
Topological data analyses are rapidly turning into key tools for quantifying large volumes of neurobiological data, e.g., for organizing the spiking outputs of large neuronal ensembles and thus gaining insights into the information produced…
We develop of a line of work initiated by Curto and Itskov towards understanding the amount of information contained in the spike trains of hippocampal place cells via topology considerations. Previously, it was established that simply…
The mammalian hippocampus plays a principal role in producing a cognitive map of space---an internalized representation of the animal's environment. The neuronal mechanisms producing this map depend primarily on the temporal structure of…
While cognitive representations of an environment can last for days and even months, the synaptic architecture of the neuronal networks that underlie these representations constantly changes due to various forms of synaptic and structural…
Spatial learning across many species is impaired by lesions in the hippocampus, a subcortical brain structure whose cellular composition changes substantially over its 5 to 6 week lifetime from mainly excitatory neurons during development…
The hippocampal formation is thought to learn spatial maps of environments, and in many models this learning process consists of forming a sensory association for each location in the environment. This is inefficient, akin to learning a…
The proposed analysis of the currently available experimental results concerning the neural cell activity in the brain area known as hippocampus suggests a particular mechanism of spatial information and memory processing. Below it is…
In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…
Mammalian hippocampus plays a key role in spatial learning and memory, but the exact nature of the hippocampal representation of space is still being explored. Recently, there has been a fair amount of success in modeling hippocampal…
The human brain possesses the extraordinary capability to contextualize the information it receives from our environment. The entorhinal-hippocampal plays a critical role in this function, as it is deeply engaged in memory processing and…
The vertebrate hippocampus is believed to use recurrent connectivity in area CA3 to support episodic memory recall from partial cues. This brain area also contains place cells, whose location-selective firing fields implement maps…
The hippocampus supports spatial navigation by encoding cognitive maps through collective place cell activity. We model the place cell population as non-negative spatial embeddings derived from the spectral decomposition of multi-step…
Learning and interpreting the structure of the environment is an innate feature of biological systems, and is integral to guiding flexible behaviours for evolutionary viability. The concept of a cognitive map has emerged as one of the…
Topological techniques have become a popular tool for studying information flows in neural networks. In particular, simplicial homology theory is used to analyze how cognitive representations of space emerge from large conglomerates of…