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The ability to generate synthetic medical images is useful for data augmentation, domain transfer, and out-of-distribution detection. However, generating realistic, high-resolution medical images is challenging, particularly for Full Field…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Dimitrios Korkinof , Tobias Rijken , Michael O'Neill , Joseph Yearsley , Hugh Harvey , Ben Glocker

Radiomics is an active area of research focusing on high throughput feature extraction from medical images with a wide array of applications in clinical practice, such as clinical decision support in oncology. However, noise in low dose…

Quantitative Methods · Quantitative Biology 2021-09-07 Junhua Chen , Inigo Bermejo , Andre Dekker , Leonard Wee

Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Yiqing Shen , Bingxin Zhou , Xinye Xiong , Ruitian Gao , Yu Guang Wang

AI requires extensive datasets, while medical data is subject to high data protection. Anonymization is essential, but poses a challenge for some regions, such as the head, as identifying structures overlap with regions of clinical…

Purpose The purpose of this study was to develop and evaluate a deep neural network (DNN) capable of generating flat-panel detector (FPD) images from digitally reconstructed radiography (DRR) images in lung cancer treatment, with the aim of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Chisako Hayashi , Shinichiro Mori , Yasukuni Mori , Lim Taehyeung , Hiroki Suyari , Hitoshi Ishikawa

Accurate synthesis of a full 3D MR image containing tumours from available MRI (e.g. to replace an image that is currently unavailable or corrupted) would provide a clinician as well as downstream inference methods with important…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Raghav Mehta , Tal Arbel

State-of-the-art deep learning methods for image processing are evolving into increasingly complex meta-architectures with a growing number of modules. Among them, region-based fully convolutional networks (R-FCN) and deformable…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Stephen Morrell , Zbigniew Wojna , Can Son Khoo , Sebastien Ourselin , Juan Eugenio Iglesias

Magnetic resonance imaging (MRI) is increasingly utilized for image-guided radiotherapy due to its outstanding soft-tissue contrast and lack of ionizing radiation. However, geometric distortions caused by gradient nonlinearity (GNL) limit…

We introduce RadiomicsFill, a synthetic tumor generator conditioned on radiomics features, enabling detailed control and individual manipulation of tumor subregions. This conditioning leverages conventional high-dimensional features of the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Inye Na , Jonghun Kim , Hyunjin Park

Deep denoising models require extensive real-world training data, which is challenging to acquire. Current noise synthesis techniques struggle to accurately model complex noise distributions. We propose a novel Realistic Noise Synthesis…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Qi Wu , Mingyan Han , Ting Jiang , Chengzhi Jiang , Jinting Luo , Man Jiang , Haoqiang Fan , Shuaicheng Liu

Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

Timely brain tumor diagnosis remains challenging in low-resource clinical environments where expert neuroradiology interpretation, high-end MRI hardware, and invasive biopsy procedures may be limited. Although deep learning has achieved…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Areeb Ehsan

One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Magnetic Resonance Imaging (MRI) is a vital modality for gaining precise anatomical information, and it plays a significant role in medical imaging for diagnosis and therapy planning. Image synthesis problems have seen a revolution in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Drici Mourad , Kazeem Oluwakemi Oseni

Generative Adversarial Networks (GAN) have shown potential in expanding limited medical imaging datasets. This study explores how different ratios of GAN-generated and real brain tumor MRI images impact the performance of a CNN in…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Mahin Montasir Afif , Abdullah Al Noman , K. M. Tahsin Kabir , Md. Mortuza Ahmmed , Md. Mostafizur Rahman , Mufti Mahmud , Md. Ashraful Babu

Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Hoo-Chang Shin , Neil A Tenenholtz , Jameson K Rogers , Christopher G Schwarz , Matthew L Senjem , Jeffrey L Gunter , Katherine Andriole , Mark Michalski

Cone Beam Computed Tomography (CBCT) finds diverse applications in medicine. Ensuring high image quality in CBCT scans is essential for accurate diagnosis and treatment delivery. Yet, the susceptibility of CBCT images to noise and artifacts…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Yunkui Pang , Yilin Liu , Xu Chen , Pew-Thian Yap , Jun Lian

This paper studies a combination of generative Markov random field (MRF) models and discriminatively trained deep convolutional neural networks (dCNNs) for synthesizing 2D images. The generative MRF acts on higher-levels of a dCNN feature…

Computer Vision and Pattern Recognition · Computer Science 2016-01-19 Chuan Li , Michael Wand

We introduce a generative smoothness regularization on manifolds (SToRM) model for the recovery of dynamic image data from highly undersampled measurements. The model assumes that the images in the dataset are non-linear mappings of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Stanley Kruger , Mathews Jacob