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Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…
Recent advances in deep learning have led to interest in training deep learning models on longitudinal healthcare records to predict a range of medical events, with models demonstrating high predictive performance. Predictive performance is…
Deep learning methods have shown promising performance in fault diagnosis for multimode process. Most existing studies assume that the collected health state categories from different operating modes are identical. However, in real…
Multivariate dynamical processes can often be intuitively described by a weighted connectivity graph between components representing each individual time-series. Even a simple representation of this graph as a Pearson correlation matrix may…
When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…
Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…
Transformer-based models have become state-of-the-art tools in various machine learning tasks, including time series classification, yet their complexity makes understanding their internal decision-making challenging. Existing…
For many complex diseases, there is a wide variety of ways in which an individual can manifest the disease. The challenge of personalized medicine is to develop tools that can accurately predict the trajectory of an individual's disease,…
Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent…
Computational models that forecast the progression of Alzheimer's disease at the patient level are extremely useful tools for identifying high risk cohorts for early intervention and treatment planning. The state-of-the-art work in this…
Deep learning has enabled breakthroughs in automated diagnosis from medical imaging, with many successful applications in ophthalmology. However, standard medical image classification approaches only assess disease presence at the time of…
We propose an attention-based method that aggregates local image features to a subject-level representation for predicting disease severity. In contrast to classical deep learning that requires a fixed dimensional input, our method operates…
Recently several deep learning based models have been proposed for end-to-end learning of dialogs. While these models can be trained from data without the need for any additional annotations, it is hard to interpret them. On the other hand,…
Recent advances in deep learning have enabled the development of automated frameworks for analysing medical images and signals, including analysis of cervical cancer. Many previous works focus on the analysis of isolated cervical cells, or…
Multivariate time series (MTS) are ubiquitous in domains such as healthcare, climate science, and industrial monitoring, but their high dimensionality, limited labeled data, and non-stationary nature pose significant challenges for…
Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…
Sleep disorders have a major impact on both lifestyle and health. Effective sleep disorder prediction from lifestyle and physiological data can provide essential details for early intervention. This research utilizes three deep time series…
Dynamical systems running on the top of complex networks has been extensively investigated for decades. But this topic still remains among the most relevant issues in complex network theory due to its range of applicability. The contact…
Accurate diagnosis of Parkinson disease, especially in its early stages, can be a challenging task. The application of machine learning techniques helps improve the diagnostic accuracy of Parkinson disease detection but only few studies…
We present a systematic study of medical-domain interpretability in Large Language Models (LLMs). We study how the LLMs both represent and process medical knowledge through four different interpretability techniques: (1) UMAP projections of…