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Glaucoma causes an irreversible damage to retinal nerve fibers which results in vision loss, if undetected in early stage. Therefore, diagnosis of glaucoma in its early stage may prevent further vision loss. In this paper, we propose a…
Glaucoma is one of the ophthalmic diseases that may cause blindness, for which early detection and treatment are very important. Fundus images and optical coherence tomography (OCT) images are both widely-used modalities in diagnosing…
It is feasible to recognize the presence and seriousness of eye disease by investigating the progressions in retinal biological structure. Fundus examination is a diagnostic procedure to examine the biological structure and anomaly of the…
Optical coherence tomography (OCT) is a non-invasive imaging technique that can produce images of the eye at the microscopic level. OCT image segmentation to localise retinal layer boundaries is a fundamental procedure for diagnosing and…
Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…
Objective: (1) To assess whether ONH biomechanics improves prediction of three progressive visual field loss patterns in glaucoma; (2) to use explainable AI to identify strain-sensitive ONH regions contributing to these predictions.…
Computer-aided detection or decision support systems aim to improve breast cancer screening programs by helping radiologists to evaluate digital mammography (DM) exams. Commonly such methods proceed in two steps: selection of candidate…
We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…
In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…
A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…
To investigate whether and to what extent central serous chorioretinopathy (CSC) depicted on color fundus photographs can be assessed using deep learning technology. We collected a total of 2,504 fundus images acquired on different…
Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…
Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…
Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective…
Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…
Glaucoma is a chronic neurodegenerative condition that can lead to blindness. Early detection and curing are very important in stopping the disease from getting worse for glaucoma patients. The 2D fundus images and optical coherence…
Purpose: To evaluate nerve fiber layer (NFL) reflectance for glaucoma diagnosis using a large dataset. Methods: Participants were imaged with 4.9mm ONH scans using spectral-domain optical coherence tomography (OCT). The NFL reflectance map…
In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…
Significant advancements in AI-driven multimodal medical image diagnosis have led to substantial improvements in ophthalmic disease identification in recent years. However, acquiring paired multimodal ophthalmic images remains prohibitively…
Glaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate…