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Exploring the complex structure of the human brain is crucial for understanding its functionality and diagnosing brain disorders. Thanks to advancements in neuroimaging technology, a novel approach has emerged that involves modeling the…

Machine Learning · Computer Science 2024-06-06 Xuexiong Luo , Jia Wu , Jian Yang , Shan Xue , Amin Beheshti , Quan Z. Sheng , David McAlpine , Paul Sowman , Alexis Giral , Philip S. Yu

Hyperbolic geometry has been successfully applied in modeling brain cortical and subcortical surfaces with general topological structures. However such approaches, similar to other surface based brain morphology analysis methods, usually…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 J. Zhang , Q. Dong , J. Shi , Q. Li , C. M. Stonnington , B. A. Gutman , K. Chen , E. M. Reiman , R. J. Caselli , P. M. Thompson , J. Ye , Y. Wang

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

In brain connectomics, the cortical surface is parcellated into different regions of interest (ROIs) prior to statistical analysis. The brain connectome for each individual can then be represented as a graph, with the nodes corresponding to…

Methodology · Statistics 2020-10-07 Steven Winter , Zhengwu Zhang , David Dunson

Neural codes are binary codes that are used for information processing and representation in the brain. In previous work, we have shown how an algebraic structure, called the {\it neural ring}, can be used to efficiently encode geometric…

Neurons and Cognition · Quantitative Biology 2019-02-14 Carina Curto , Nora Youngs

The morphological fingerprint in the brain is capable of identifying the uniqueness of an individual. However, whether such individual patterns are present in perinatal brains, and which morphological attributes or cortical regions better…

Machine Learning · Computer Science 2023-11-28 Boyang Wang , Weihao Zheng , Ying Wang , Zhe Zhang , Yuchen Sheng , Minmin Wang

Cytoarchitecture describes the spatial organization of neuronal cells in the brain, including their arrangement into layers and columns with respect to cell density, orientation, or presence of certain cell types. It allows to segregate the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Christian Schiffer , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

One of the primary objectives of human brain mapping is the division of the cortical surface into functionally distinct regions, i.e. parcellation. While it is generally agreed that at macro-scale different regions of the cortex have…

Neurons and Cognition · Quantitative Biology 2017-03-06 Daniel Moyer , Boris A Gutman , Neda Jahanshad , Paul M. Thompson

Many longitudinal neuroimaging studies aim to improve the understanding of brain aging and diseases by studying the dynamic interactions between brain function and cognition. Doing so requires accurate encoding of their multidimensional…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Yixin Wang , Wei Peng , Yu Zhang , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

The cerebral cortex performs higher-order brain functions and is thus implicated in a range of cognitive disorders. Current analysis of cortical variation is typically performed by fitting surface mesh models to inner and outer cortical…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Samuel Budd , Prachi Patkee , Ana Baburamani , Mary Rutherford , Emma C. Robinson , Bernhard Kainz

One of the essential tasks in connectomics is the morphology analysis of neurons and organelles like mitochondria to shed light on their biological properties. However, these biological objects often have tangled parts or complex branching…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Abhimanyu Talwar , Zudi Lin , Donglai Wei , Yuesong Wu , Bowen Zheng , Jinglin Zhao , Won-Dong Jang , Xueying Wang , Jeff W. Lichtman , Hanspeter Pfister

Predictive coding has emerged as an influential normative model of neural computation, with numerous extensions and applications. As such, much effort has been put into mapping PC faithfully onto the cortex, but there are issues that remain…

Neurons and Cognition · Quantitative Biology 2023-03-07 Siavash Golkar , Tiberiu Tesileanu , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

The geometry of neurons is known to be important for their functions. Hence, neurons are often classified by their morphology. Two recent methods, persistent homology and the topological morphology descriptor, assign a morphology descriptor…

Neurons and Cognition · Quantitative Biology 2022-04-08 David Beers , Despoina Goniotaki , Diane P. Hanger , Alain Goriely , Heather A. Harrington

We introduce a method that takes advantage of high-quality pretrained multimodal representations to explore fine-grained semantic networks in the human brain. Previous studies have documented evidence of functional localization in the…

Artificial Intelligence · Computer Science 2023-06-07 Cory Efird , Alex Murphy , Joel Zylberberg , Alona Fyshe

Encoding and decoding models are widely used in systems, cognitive, and computational neuroscience to make sense of brain-activity data. However, the interpretation of their results requires care. Decoding models can help reveal whether…

Neurons and Cognition · Quantitative Biology 2019-04-29 Nikolaus Kriegeskorte , Pamela K. Douglas

Studying the cellular architecture of the human cerebral cortex is critical for understanding brain organization and function. It requires investigating complex texture patterns in histological images, yet automatic methods that scale…

Neurons and Cognition · Quantitative Biology 2026-03-06 Christian Schiffer , Zeynep Boztoprak , Jan-Oliver Kropp , Julia Thönnißen , Katia Berr , Hannah Spitzer , Katrin Amunts , Timo Dickscheid

Unsupervised graph representation learning has recently gained interest in several application domains such as neuroscience, where modeling the diverse morphology of cell types in the brain is one of the key challenges. It is currently…

Machine Learning · Statistics 2023-07-12 Marissa A. Weis , Laura Hansel , Timo Lüddecke , Alexander S. Ecker

The surface morphology of the developing mammalian brain is crucial for understanding brain function and dysfunction. Computational modeling offers valuable insights into the underlying mechanisms for early brain folding. Recent findings…

Neurons and Cognition · Quantitative Biology 2024-09-06 Jixin Hou , Zhengwang Wu , Xianyan Chen , Li Wang , Dajiang Zhu , Tianming Liu , Gang Li , Xianqiao Wang

We consider constrained variants of graph homomorphisms such as embeddings, monomorphisms, full homomorphisms, surjective homomorpshims, and locally constrained homomorphisms. We also introduce a new variation on this theme which derives…

Combinatorics · Mathematics 2014-04-23 Yangjing Long