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Modern imaging techniques at the molecular scale rely on utilizing novel coherent light sources like X-ray free electron lasers for the ultimate goal of visualizing such objects as individual biomolecules rather than crystals. Here, unlike…

This paper proposes a particle volume reconstruction directly from an in-line hologram using a deep neural network. Digital holographic volume reconstruction conventionally uses multiple diffraction calculations to obtain sectional…

Image and Video Processing · Electrical Eng. & Systems 2019-03-27 Tomoyoshi Shimobaba , Takayuki Takahashi , Yota Yamamoto , Yutaka Endo , Atsushi Shiraki , Takashi Nishitsuji , Naoto Hoshikawa , Takashi Kakue , Tomoyosh Ito

Lensless in-line holography is a simple, portable, and cost-effective method of imaging especially for the biomedical microscopy applications. We propose a multiplicative gradient descent optimization based method to obtain multi-depth…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Methods of three-dimensional deconvolution with a point-spread function as frequently employed in optical microscopy to reconstruct true three-dimensional distribution of objects are extended to holographic reconstructions. Two such schemes…

Optics · Physics 2017-08-09 Tatiana Latychevskaia , Fabian Gehri , Hans-Werner Fink

Hyperspectral image classification (HIC) is an active research topic in remote sensing. Hyperspectral images typically generate large data cubes posing big challenges in data acquisition, storage, transmission and processing. To overcome…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Hao Zhang , Xu Ma , Xianhong Zhao , Gonzalo R. Arce

Accurate assessment of human epidermal growth factor receptor 2 (HER2) expression is critical for breast cancer diagnosis, prognosis, and therapy selection; yet, most existing digital HER2 scoring methods rely on bulky and expensive optical…

Medical Physics · Physics 2026-01-27 Che-Yung Shen , Xilin Yang , Yuzhu Li , Leon Lenk , Aydogan Ozcan

High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur

Compressed sensing (CS) is a signal processing framework for efficiently reconstructing a signal from a small number of measurements, obtained by linear projections of the signal. Block-based CS is a lightweight CS approach that is mostly…

Computer Vision and Pattern Recognition · Computer Science 2016-06-07 Amir Adler , David Boublil , Michael Elad , Michael Zibulevsky

Visual grouping is a key mechanism in human scene perception. There, it belongs to the subconscious, early processing and is key prerequisite for other high level tasks such as recognition. In this paper, we introduce an efficient, realtime…

Computer Vision and Pattern Recognition · Computer Science 2016-09-23 Dominik Alexander Klein , Dirk Schulz , Armin Bernd Cremers

Hyperspectral imaging (HSI) analysis faces computational bottlenecks due to massive data volumes that exceed available memory. While foundation models pre-trained on large remote sensing datasets show promise, their learned representations…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yu-Tang Chang , Pin-Wei Chen , Shih-Fang Chen

Empirical investigation of the quintillion-scale, functionally diverse antibody repertoires that can be generated synthetically or naturally is critical for identifying potential biotherapeutic leads, yet remains burdensome. We present…

The study explores machine learning methods for revealing chemical sensitivity in Helium spin-echo spectroscopy, in order to obtain ultra-sensitive surface analytic technique. We model bi-species co-adsorbed systems and demonstrate that by…

Chemical Physics · Physics 2020-12-04 Reinis Irmejs , Nadav Avidor

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Recently, a number of competitive methods have tackled unsupervised representation learning by maximising the mutual information between the representations produced from augmentations. The resulting representations are then invariant to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Luke Nicholas Darlow , Amos Storkey

In the fields of photogrammetry, computer vision and computer graphics, the task of neural 3D scene reconstruction has led to the exploration of various techniques. Among these, 3D Gaussian Splatting stands out for its explicit…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Miriam Jäger , Theodor Kapler , Michael Feßenbecker , Felix Birkelbach , Markus Hillemann , Boris Jutzi

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

We present a fast general-purpose algorithm for high-throughput clustering of data "with a two dimensional organization". The algorithm is designed to be implemented with FPGAs or custom electronics. The key feature is a processing time…

Instrumentation and Detectors · Physics 2015-05-14 A. Annovi , M. Beretta

Single-beam scanning electron microscopes (SEM) are widely used to acquire massive data sets for biomedical study, material analysis, and fabrication inspection. Datasets are typically acquired with uniform acquisition: applying the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Lu Mi , Hao Wang , Yaron Meirovitch , Richard Schalek , Srinivas C. Turaga , Jeff W. Lichtman , Aravinthan D. T. Samuel , Nir Shavit

Machine-learning-based methods can be developed for the reconstruction of clusters in segmented detectors for high energy physics experiments. Convolutional neural networks with autoencoder architecture trained on labeled data from a…

Instrumentation and Detectors · Physics 2025-06-02 Kalina Dimitrova , Venelin Kozhuharov , Ruslan Nastaev , Peicho Petkov

Existing three-dimensional (3-D) compressive sensing-based millimeter-wave (MMW) imaging methods require a large-scale storage of the sensing matrix and immense computations owing to the high dimension matrix-vector model employed in the…

Signal Processing · Electrical Eng. & Systems 2018-12-26 Shiyong Li , Guoqiang Zhao , Houjun Sun , Moeness Amin