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Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

Neurons and Cognition · Quantitative Biology 2011-09-23 Chun-Chung Chen , David Jasnow

Neuronal oscillations are closely related to the symptoms of Parkinson's disease (PD). In this study, we explore how random fluctuations (or "stochastic inputs") affect these oscillations in brain states, which reflect the collective…

Neurons and Cognition · Quantitative Biology 2025-02-24 Thoa Thieu , Roderick Melnik

Bursting neurons fire rapid sequences of action potential spikes followed by a quiescent period. The basic dynamical mechanism of bursting is the slow currents that modulate a fast spiking activity caused by rapid ionic currents. Minimal…

Chaotic Dynamics · Physics 2015-02-16 Fabiano A. S. Ferrari , Ricardo L. Viana , Sérgio R. Lopes , Ruedi Stoop

Complex spatiotemporal patterns, called chimera states, consist of coexisting coherent and incoherent domains and can be observed in networks of coupled oscillators. The interplay of synchrony and asynchrony in complex brain networks is an…

Adaptation and Self-Organizing Systems · Physics 2019-06-20 Teresa Chouzouris , Iryna Omelchenko , Anna Zakharova , Jaroslav Hlinka , Premysl Jiruska , Eckehard Schöll

The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct…

Neurons and Cognition · Quantitative Biology 2024-06-17 Zhichao Liang , Guanyi Zhao , Yinuo Zhang , Weiting Sun , Jingzhe Lin , Jialin Wang , Quanying Liu

Synchronization is a widespread phenomenon in the brain. Despite numerous studies, the specific parameter configurations of the synaptic network structure and learning rules needed to achieve robust and enduring synchronization in neurons…

Neurons and Cognition · Quantitative Biology 2023-08-15 Marius E. Yamakou , Mathieu Desroches , Serafim Rodrigues

We propose another integrate-and-fire model as a single neuron model. We study a globally coupled noisy integrate-and-fire model with inhibitory interaction using the Fokker-Planck equation and the Langevin equation, and find a reentrant…

Neurons and Cognition · Quantitative Biology 2009-11-11 H. Sakaguchi , S. Tobiishi

New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered…

Neurons and Cognition · Quantitative Biology 2009-12-14 Casey M. Schneider-Mizell , Jack M. Parent , Eshel Ben-Jacob , Michal Zochowski , Leonard M. Sander

Many biological processes involve synchronization between nonequivalent systems, i.e, systems where the difference is limited to a rather small parameter mismatch. The maintenance of the synchronized regime in this cases is energetically…

Artificial Intelligence · Computer Science 2012-04-19 A. Moujahid , A. D'Anjou , F. J. Torrealdea , C. Sarasola

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from experience to sharp our memory. In the nervous system, the brain…

Neurons and Cognition · Quantitative Biology 2022-06-20 Thi Kim Thoa Thieu , Roderick Melnik

Seizure and synchronization are related to each other in complex manner. Altered synchrony has been implicated in loss of consciousness during partial seizures. However, the mechanism of altered consciousness following termination of…

Neurons and Cognition · Quantitative Biology 2018-01-30 Puneet Dheer , Sandipan Pati , Srinath Jayachandran , Kaushik Kumar Majumdar

Efficient Balanced Networks (EBNs) are networks of spiking neurons in which excitatory and inhibitory synaptic currents are balanced on a short timescale, leading to desirable coding properties such as high encoding precision, low firing…

Emerging Technologies · Computer Science 2021-02-15 Julian Büchel , Jonathan Kakon , Michel Perez , Giacomo Indiveri

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Jun-nosuke Teramae , Tomoki Fukai

There is increasing evidence for specific cortical and subcortical large-scale human epileptic networks to be involved in the generation, spread, and termination of not only primary generalized but also focal onset seizures. The complex…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Marie-Therese Kuhnert , Christian E. Elger , Klaus Lehnertz

Correlations in spike-train ensembles can seriously impair the encoding of information by their spatio-temporal structure. An inevitable source of correlation in finite neural networks is common presynaptic input to pairs of neurons. Recent…

Neurons and Cognition · Quantitative Biology 2015-06-04 Tom Tetzlaff , Moritz Helias , Gaute T. Einevoll , Markus Diesmann

A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with…

Medical Physics · Physics 2012-09-26 Wei Cheng , Xuejuan Zhang , Ge Tian , Jianfeng Feng , Zhengge Wang , Zhiqiang Zhang , GuangMing Lu

Recordings from area V4 of monkeys have revealed that when the focus of attention is on a visual stimulus within the receptive field of a cortical neuron, two distinct changes can occur: The firing rate of the neuron can change and there…

Neurons and Cognition · Quantitative Biology 2007-05-23 Paul H. E. Tiesinga , Jean-Marc Fellous , Emilio Salinas , Jorge V. Jose , Terrence J. Sejnowski

Brain plasticity, also known as neuroplasticity, is a fundamental mechanism of neuronal adaptation in response to changes in the environment or due to brain injury. In this review, we show our results about the effects of synaptic…