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Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller

To perform well, most deep learning based image classification systems require large amounts of data and computing resources. These constraints make it difficult to quickly personalize to individual users or train models outside of fairly…

Computer Vision and Pattern Recognition · Computer Science 2021-04-26 Nat Roth , Justin Wagle

Accurate and efficient cell nuclei detection and classification in histopathological Whole Slide Images (WSIs) are pivotal for digital pathology applications. Traditional cell segmentation approaches, while commonly used, are…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Oscar Pina , Eduard Dorca , Verónica Vilaplana

Recent advances in optical technology have significantly enhanced the resolution of imaging of living cells, achieving nanometer-scale precision. However, the crowded three-dimensional environment within cells presents a challenge for…

Optics · Physics 2024-11-20 Vahid Nasirimarekani , Zuzana Ditte , Eberhard Bodenschatz

This paper presents an approach for automatic detection of Munro's Microabscess in stratum corneum (SC) of human skin biopsy in order to realize a machine assisted diagnosis of Psoriasis. The challenge of detecting neutrophils in presence…

Computer Vision and Pattern Recognition · Computer Science 2018-08-22 Anabik Pal , Akshay Chaturvedi , Utpal Garain , Aditi Chandra , Raghunath Chatterjee , Swapan Senapati

Few-shot segmentation (FSS) is a dense prediction task that aims to infer the pixel-wise labels of unseen classes using only a limited number of annotated images. The key challenge in FSS is to classify the labels of query pixels using…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Wenbo Xu , Huaxi Huang , Ming Cheng , Litao Yu , Qiang Wu , Jian Zhang

Segmentation of cell nuclei in microscopy images is a prevalent necessity in cell biology. Especially for three-dimensional datasets, manual segmentation is prohibitively time-consuming, motivating the need for automated methods.…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Peter Hirsch , Dagmar Kainmueller

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Anomaly detection, the task of identifying unusual samples in data, often relies on a large set of training samples. In this work, we consider the setting of few-shot anomaly detection in images, where only a few images are given at…

Computer Vision and Pattern Recognition · Computer Science 2021-04-30 Shelly Sheynin , Sagie Benaim , Lior Wolf

The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Xiaoang Shen , Guokai Zhang , Huilin Lai , Jihao Luo , Jianwei Lu , Ye Luo

At present spoofing attacks via which biometric system is potentially vulnerable against a fake biometric characteristic, introduces a great challenge to recognition performance. Despite the availability of a broad range of presentation…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Avantika Singh , Gaurav Jaswal , Aditya Nigam

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

Labeling data is often expensive and time-consuming, especially for tasks such as object detection and instance segmentation, which require dense labeling of the image. While few-shot object detection is about training a model on novel…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Gabriel Huang , Issam Laradji , David Vazquez , Simon Lacoste-Julien , Pau Rodriguez

The necessity of large amounts of labeled data to train deep models, especially in medical imaging creates an implementation bottleneck in resource-constrained settings. In Insite (labelINg medical imageS usIng submodular funcTions and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Akshat Gautam , Anurag Shandilya , Akshit Srivastava , Venkatapathy Subramanian , Ganesh Ramakrishnan , Kshitij Jadhav

This paper considers (partial) identification of a variety of counterfactual parameters in binary response models with possibly endogenous regressors. Our framework allows for nonseparable index functions with multi-dimensional latent…

Econometrics · Economics 2022-07-26 Jiaying Gu , Thomas M. Russell

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Clinical biosensors with low detection limit hold significant promise in the early diagnosis of debilitating diseases. Recent progress in sensor development has led to the demonstration of detection capable of detecting target molecules…

Medical Physics · Physics 2019-12-05 Tuhin Chakrabortty , Chandra R. Murthy , Manoj Varma

The sensitivity of imaging spectroscopy to haemoglobin derivatives makes it a promising tool for detecting blood. However, due to complexity and high dimensionality of hyperspectral images, the development of hyperspectral blood detection…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Michał Romaszewski , Przemysław Głomb , Arkadiusz Sochan , Michał Cholewa

Microscopy data collections are becoming larger and more frequent. Accurate and precise quantitative analysis tools like cell instance segmentation are necessary to benefit from them. This is challenging due to the variability in the data,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Ram J. Zaveri , Voke Brume , Gianfranco Doretto