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Related papers: A Bayesian Nonparametric Model for Zero-Inflated O…

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This review provides a systematic overview of methods that combine covariate-based clustering of observational units (patients) with outcome models for clinical studies. We distinguish between informed-cluster models, where the outcome…

Understanding treatment effect heterogeneity is vital for scientific and policy research. However, identifying and evaluating heterogeneous treatment effects pose significant challenges due to the typically unknown subgroup structure.…

Methodology · Statistics 2024-11-05 Kwangho Kim , Jisu Kim , Larry A. Wasserman , Edward H. Kennedy

Performing causal inference in observational studies requires we assume confounding variables are correctly adjusted for. G-computation methods are often used in these scenarios, with several recent proposals using Bayesian versions of…

Methodology · Statistics 2021-10-25 Daniel Daly-Grafstein , Paul Gustafson

Healthcare cost prediction is a challenging task due to the high-dimensionality and high correlation among covariates. Additionally, the skewed, heavy-tailed, and often multi-modal nature of cost data can complicate matters further due to…

Methodology · Statistics 2023-03-13 Zhengxiao Li , Yifan Huang , Yang Cao

Many data sets cannot be accurately described by standard probability distributions due to the excess number of zero values present. For example, zero-inflation is prevalent in microbiome data and single-cell RNA sequencing data, which…

Methodology · Statistics 2024-11-20 Max Beveridge , Zach Goldstein , Hee Cheol Chung

Bayesian causal inference offers a principled approach to policy evaluation of proposed interventions on mediators or time-varying exposures. We outline a general approach to the estimation of causal quantities for settings with…

Methodology · Statistics 2019-02-28 Leah Comment , Brent A. Coull , Corwin Zigler , Linda Valeri

Analyzing overdispersed, zero-inflated, longitudinal count data poses significant modeling and computational challenges, which standard count models (e.g., Poisson or negative binomial mixed effects models) fail to adequately address. We…

Methodology · Statistics 2026-02-11 John Barrera , Ana Arribas-Gil , Dae-Jin Lee , Cristian Meza

In estimating the causal effect of a continuous exposure or treatment, it is important to control for all confounding factors. However, most existing methods require parametric specification for how control variables influence the outcome…

Applications · Statistics 2020-07-21 Spencer Woody , Carlos M. Carvalho , P. Richard Hahn , Jared S. Murray

In recent years, there has been a growing demand to discern clusters of subjects in datasets characterized by a large set of features. Often, these clusters may be highly variable in size and present partial hierarchical structures. In this…

Methodology · Statistics 2024-07-01 Lorenzo Schiavon , Mattia Stival

We present a Bayesian inference approach to estimating the cumulative mass profile and mean squared velocity profile of a globular cluster given the spatial and kinematic information of its stars. Mock globular clusters with a range of…

Astrophysics of Galaxies · Physics 2022-03-09 Gwendolyn M. Eadie , Jeremy J. Webb , Jeffrey S. Rosenthal

When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated…

Machine Learning · Computer Science 2013-02-21 George H. John , Pat Langley

One of the main unsolved problems of cosmology is how to maximize the extraction of information from nonlinear data. If the data are nonlinear the usual approach is to employ a sequence of statistics (N-point statistics, counting statistics…

Cosmology and Nongalactic Astrophysics · Physics 2018-03-07 Uros Seljak , Grigor Aslanyan , Yu Feng , Chirag Modi

We provide novel probabilistic portrayals of two multivariate models designed to handle zero-inflation in count-compositional data. We develop a new unifying framework that represents both as finite mixture distributions. One of these…

Methodology · Statistics 2026-03-31 André F. B. Menezes , Andrew C. Parnell , Keefe Murphy

A Bayesian multivariate model with a structured covariance matrix for multi-way nested data is proposed. This flexible modeling framework allows for positive and for negative associations among clustered observations, and generalizes the…

Methodology · Statistics 2024-08-27 Stef Baas , Richard J. Boucherie , Jean-Paul Fox

Most causal inference methods focus on estimating marginal average treatment effects, but many important causal estimands depend on the joint distribution of potential outcomes, including the probability of causation and proportions…

Methodology · Statistics 2025-10-16 Zach Shahn , David Madigan

In this paper we develop a likelihood-free approach for population calibration, which involves finding distributions of model parameters when fed through the model produces a set of outputs that matches available population data. Unlike…

Methodology · Statistics 2022-02-07 Christopher Drovandi , Brodie Lawson , Adrianne L Jenner , Alexander P Browning

We propose a fully Bayesian approach for causal inference with multivariate categorical data based on staged tree models, a class of probabilistic graphical models capable of representing asymmetric and context-specific dependencies. To…

Methodology · Statistics 2025-11-06 Andrea Cremaschi , Manuele Leonelli , Gherardo Varando

Motivated by parametric models for which the likelihood is analytically unavailable, numerically unstable, or prohibitively expensive to compute or optimize, we develop a prior- and likelihood-free framework for fully probabilistic…

Methodology · Statistics 2026-03-17 Leonardo Cella , Emily C. Hector

We develop a new longitudinal count data regression model that accounts for zero-inflation and spatio-temporal correlation across responses. This project is motivated by an analysis of Iowa Fluoride Study (IFS) data, a longitudinal cohort…

Methodology · Statistics 2024-12-30 Anish Mukherjee , Jeremy T. Gaskins , Shoumi Sarkar , Steven Levy , Somnath Datta

In observational studies, unmeasured confounders present a crucial challenge in accurately estimating desired causal effects. To calculate the hazard ratio (HR) in Cox proportional hazard models for time-to-event outcomes, two-stage…

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