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The realization of autonomous scientific experimentation is currently limited by LLMs' struggle to grasp the strict procedural logic and accuracy required by biological protocols. To address this fundamental challenge, we present…

Computation and Language · Computer Science 2026-01-22 Yuyang Liu , Liuzhenghao Lv , Xiancheng Zhang , Jingya Wang Li Yuan , Yonghong Tian

Big data repositories from online learning platforms such as Massive Open Online Courses (MOOCs) represent an unprecedented opportunity to advance research on education at scale and impact a global population of learners. To date, such…

Software Engineering · Computer Science 2018-08-23 Josh Gardner , Christopher Brooks , Juan Miguel L. Andres , Ryan Baker

Microservice architectures and design patterns enhance the development of large-scale applications by promoting flexibility. Industrial practitioners perceive the importance of applying architectural patterns but they struggle to quantify…

Software Engineering · Computer Science 2024-09-09 Willem Meijer , Catia Trubiani , Aldeida Aleti

Surrogate networks can constitute suitable replacements for real networks, in particular to study dynamical processes on networks, when only incomplete or limited datasets are available. As empirical datasets most often present complex…

Physics and Society · Physics 2025-04-17 Giulia Cencetti , Alain Barrat

Cloud service providers commonly use standard benchmarks like TPC-H and TPC-DS to evaluate and optimize cloud data analytics systems. However, these benchmarks rely on fixed query patterns and fail to capture the real execution statistics…

Modern language models are trained almost exclusively on token sequences produced by a fixed tokenizer, an external lossless compressor often over UTF-8 byte sequences, thereby coupling the model to that compressor. This work introduces…

Computation and Language · Computer Science 2026-05-15 Lin Zheng , Xinyu Li , Qian Liu , Xiachong Feng , Lingpeng Kong

Complex systems are increasingly explored through simulation-driven engineering workflows that combine physics-based and empirical models with optimization and analytics. Despite their power, these workflows face two central obstacles: (1)…

Studying the topology of so-called real networks, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that networks are…

Applications · Statistics 2010-07-27 Etienne Birmele

Topic models provide a useful method for dimensionality reduction and exploratory data analysis in large text corpora. Most approaches to topic model inference have been based on a maximum likelihood objective. Efficient algorithms exist…

Machine Learning · Computer Science 2012-12-20 Sanjeev Arora , Rong Ge , Yoni Halpern , David Mimno , Ankur Moitra , David Sontag , Yichen Wu , Michael Zhu

Recently, large language models (LLMs) and multimodal large language models (MLLMs) have demonstrated promising results on document visual question answering (VQA) task, particularly after training on document instruction datasets. An…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Yufan Shen , Chuwei Luo , Zhaoqing Zhu , Yang Chen , Qi Zheng , Zhi Yu , Jiajun Bu , Cong Yao

We propose DFModel, a modeling framework for mapping dataflow computation graphs onto large-scale systems. Mapping a workload to a system requires optimizing dataflow mappings at various levels, including the inter-chip (between chips)…

Hardware Architecture · Computer Science 2024-12-24 Sho Ko , Nathan Zhang , Olivia Hsu , Ardavan Pedram , Kunle Olukotun

As Large Language Models (LLMs) are increasingly used for long-duration tasks, maintaining effective long-term memory has become a critical challenge. Current methods often face a trade-off between cost and accuracy. Simple storage methods…

Information Retrieval · Computer Science 2026-03-05 Jiejun Tan , Zhicheng Dou , Liancheng Zhang , Yuyang Hu , Yiruo Cheng , Ji-Rong Wen

A time series motif intuitively is a short time series that repeats itself approximately the same within a larger time series. Such motifs often represent concealed structures, such as heart beats in an ECG recording, the riff in a pop…

Machine Learning · Computer Science 2024-04-18 Patrick Schäfer , Ulf Leser

In many randomized experiments, the treatment effect of the long-term metric (i.e. the primary outcome of interest) is often difficult or infeasible to measure. Such long-term metrics are often slow to react to changes and sufficiently…

Many deep learning tasks require annotations that are too time consuming for human operators, resulting in small dataset sizes. This is especially true for dense regression problems such as crowd counting which requires the location of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Arian Bakhtiarnia , Qi Zhang , Alexandros Iosifidis

The use of approximation is fundamental in computational science. Almost all computational methods adopt approximations in some form in order to obtain a favourable cost/accuracy trade-off and there are usually many approximations that…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-14 Michael A. Johnston , Vassilis Vassiliadis

Time series prediction is of great significance in many applications and has attracted extensive attention from the data mining community. Existing work suggests that for many problems, the shape in the current time series may correlate an…

Artificial Intelligence · Computer Science 2017-12-05 Yuanduo He , Xu Chu , Juguang Peng , Jingyue Gao , Yasha Wang

Sequence discovery tools play a central role in several fields of computational biology. In the framework of Transcription Factor binding studies, motif finding algorithms of increasingly high performance are required to process the big…

Quantitative Methods · Quantitative Biology 2014-08-27 Nicolò Colombo , Nikos Vlassis

While Large Language Models (LLMs) show significant potential in hardware engineering, current benchmarks suffer from saturation and limited task diversity, failing to reflect LLMs' performance in real industrial workflows. To address this…

Artificial Intelligence · Computer Science 2026-02-03 Zhongkai Yu , Chenyang Zhou , Yichen Lin , Hejia Zhang , Haotian Ye , Junxia Cui , Zaifeng Pan , Jishen Zhao , Yufei Ding

Addressing bias in the trained machine learning system often requires access to sensitive attributes. In practice, these attributes are not available either due to legal and policy regulations or data unavailability for a given demographic.…

Machine Learning · Computer Science 2023-12-27 Bhushan Chaudhary , Anubha Pandey , Deepak Bhatt , Darshika Tiwari