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This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

Classical optimization and learning-based methods are the two reigning paradigms in deformable image registration. While optimization-based methods boast generalizability across modalities and robust performance, learning-based methods…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Rohit Jena , Deeksha Sethi , Pratik Chaudhari , James C. Gee

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Tony C. W. Mok , Albert C. S. Chung

Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains unclear what current representation learning methods actually…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ivan Svatko , Maxime Sanchez , Ihab Bendidi , Gilles Cottrell , Auguste Genovesio

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi

Computerized registration between maxillofacial cone-beam computed tomography (CT) images and a scanned dental model is an essential prerequisite in surgical planning for dental implants or orthognathic surgery. We propose a novel method…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Minyoung Chung , Jingyu Lee , Wisoo Song , Youngchan Song , Il-Hyung Yang , Jeongjin Lee , Yeong-Gil Shin

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Longitudinal image registration is challenging and has not yet benefited from major performance improvements thanks to deep-learning. Inspired by Deep Image Prior, this paper introduces a different use of deep architectures as regularizers…

Deformable image registration is a fundamental task in medical image analysis and plays a crucial role in a wide range of clinical applications. Recently, deep learning-based approaches have been widely studied for deformable medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Jing Zou , Noémie Debroux , Lihao Liu , Jing Qin , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Computer vision and image processing address many challenging applications. While the last decade has seen deep neural network architectures revolutionizing those fields, early methods relied on 'classic', i.e., non-learned approaches. In…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Nati Ofir , Jean-Christophe Nebel

Whole slide image (WSI) registration is an essential task for analysing the tumour microenvironment (TME) in histopathology. It involves the alignment of spatial information between WSIs of the same section or serial sections of a tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Behnaz Elhaminia , Abdullah Alsalemi , Esha Nasir , Mostafa Jahanifar , Ruqayya Awan , Lawrence S. Young , Nasir M. Rajpoot , Fayyaz Minhas , Shan E Ahmed Raza

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Medical image registration is a fundamental and vital task which will affect the efficacy of many downstream clinical tasks. Deep learning (DL)-based deformable image registration (DIR) methods have been investigated, showing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ti Bai , Muhan Lin , Xiao Liang , Biling Wang , Michael Dohopolski , Bin Cai , Dan Nguyen , Steve Jiang

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

This document outlines a tutorial to get started with medical image registration using the open-source package DeepReg. The basic concepts of medical image registration are discussed, linking classical methods to newer methods using deep…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 N. Montana Brown , Y. Fu , S. U. Saeed , A. Casamitjana , Z. M. C. Baum , R. Delaunay , Q. Yang , A. Grimwood , Z. Min , E. Bonmati , T. Vercauteren , M. J. Clarkson , Y. Hu

Image registration is a widely-used technique in analysing large scale datasets that are captured through various imaging modalities and techniques in biomedical imaging such as MRI, X-Rays, etc. These datasets are typically collected from…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Hassan Mahmood , Asim Iqbal , Syed Mohammed Shamsul Islam

Background and Objective: In neurosurgery, fusing clinical images and depth images that can improve the information and details is beneficial to surgery. We found that the registration of face depth images was invalid frequently using…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Pengfei Li , Ziyue Ma , Hong Wang , Juan Deng , Yan Wang , Zhenyu Xu , Feng Yan , Wenjun Tu , Hong Sha