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Fisher's fundamental theorem of natural selection states that the rate of change in a population's mean fitness equals its additive genetic variance in fitness. This implies that mean fitness should not decline in a constant environment,…

Populations and Evolution · Quantitative Biology 2025-08-18 Yun-Yun Yu , Cang Hui , Tian-Jiao Feng , Cong Li , Chao Wang , Yi Tao , Rui-Wu Wang

Certain intriguing consequences of the discreteness of time on the time evolution of dynamical systems are discussed. In the discrete-time classical mechanics proposed here, there is an {\it arrow of time} that follows from the fact that…

Quantum Physics · Physics 2009-11-11 M. C. Valsakumar

Current experimental design techniques for dynamical systems often only incorporate measurement noise, while dynamical systems also involve process noise. To construct experimental designs we need to quantify their information content. The…

Methodology · Statistics 2026-03-24 Arno Strouwen , Bart M. Nicolaï , Peter Goos

Fisher information measures a disorder system, which is specified by a corresponding probability, the likelihood. In this article, we provide a bridge to connect classical and quantum mechanics by using Fisher information. Following the…

Quantum Physics · Physics 2014-12-30 Tzu-Chao Hung

Statistical learning under distributional drift remains poorly characterized, especially in closed-loop settings where learning alters the data-generating law. We introduce an intrinsic drift budget $C_T$ that quantifies cumulative…

Machine Learning · Computer Science 2026-05-19 Sofiya Zaichyk

Background: Acceleration of adaptation dynamics by stress-induced hypermutation has been found experimentally. Evolved evolvability is a prominent explanation. We investigate a more generally applicable explanation by a physical constraint.…

Biological Physics · Physics 2011-04-12 Lennart Hilbert

Recreational fishing is a highly socio-ecological process. Although recreational fisheries are self-regulating and resilient, changing anthropogenic pressure drives these fisheries to overharvest and collapse. Here, we evaluate the effect…

Populations and Evolution · Quantitative Biology 2021-02-17 Sukanta Sarkar , Arzoo Narang , Sudipta Kumar Sinha , Partha Sharathi Dutta

We consider the problem of quantum phase estimation with access to arbitrary measurements in a single suboptimal basis. The achievable sensitivity limit in this case is determined by the classical Cram\'{e}r-Rao bound with respect to the…

Quantum Physics · Physics 2019-09-19 Manuel Gessner

Biological and living systems process information across spatiotemporal scales, exhibiting the hallmark ability to constantly modulate their behavior to ever-changing and complex environments. In the presence of repeated stimuli, a…

Statistical Mechanics · Physics 2025-02-04 Giorgio Nicoletti , Matteo Bruzzone , Samir Suweis , Marco Dal Maschio , Daniel Maria Busiello

The Fisher Information Metric (FIM) and the associated Cram\'er-Rao Bound (CRB) are fundamental tools in statistical signal processing, which inform the efficient design of experiments and algorithms for estimating the underlying…

Signal Processing · Electrical Eng. & Systems 2025-05-20 Shiraz Khan , Gregory S. Chirikjian

The stochastic Kuramoto model defined on a sequence of graphs is analyzed: the emphasis is posed on the relationship between the mean field limit, the connectivity of the underlying graph and the long time behavior. We give an explicit…

Probability · Mathematics 2019-12-24 Fabio Coppini

The wave speed of a stochastic wave equation driven by Riesz noise on the unbounded multidimensional spatial domain is estimated based on discrete measurements. Central limit theorems for second-order variations of the observations in…

Statistics Theory · Mathematics 2026-02-05 Anton Tiepner , Mathias Trabs , Eric Ziebell

For a stochastic system, its evolution from one state to another can have a large number of possible paths. Non-uniformity in the field of system variables leads the local dynamics in state transition varies considerably from path to path…

Statistical Mechanics · Physics 2019-03-26 De-yu Zhong , Guang-qian Wang , Tie-jian Li , Ming-xi ZHANG , You Xia , Yu Zhang

Training-free conditional diffusion models have received great attention in conditional image generation tasks. However, they require a computationally expensive conditional score estimator to let the intermediate results of each step in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Kaiyu Song , Hanjiang Lai

We present a novel and simple method to numerically calculate Fisher Information Matrices for stochastic chemical kinetics models. The linear noise approximation is used to derive model equations and a likelihood function which leads to an…

Applications · Statistics 2015-05-27 Michal Komorowski , Maria J. Costa , David A. Rand , Michael Stumpf

Fine-tuning and naturalness, the sensitivity of low-energy observables to small changes in the fundamental parameters of a theory, are cornerstones of physics beyond the Standard Model. We propose a new measure of fine-tuning based on…

High Energy Physics - Theory · Physics 2026-05-04 James Halverson , Thomas R. Harvey , Michael Nee

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

Time change is a powerful technique for generating noises and providing flexible models. In the framework of time changed Brownian and Poisson random measures we study the existence and uniqueness of a solution to a general mean-field…

Probability · Mathematics 2016-08-23 Giulia Di Nunno , Hannes Haferkorn

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

One of the fundamental assumptions in stochastic control of continuous time processes is that the dynamics of the underlying (diffusion) process is known. This is, however, usually obviously not fulfilled in practice. On the other hand,…

Optimization and Control · Mathematics 2022-01-10 Sören Christensen , Claudia Strauch
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