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The molecular biology revolution of the last seventy five years has transformed our view of living systems. Scientific explanations of biological phenomena are now synonymous with the identification of the genes, proteins, and signaling…
I examine some recent findings in cosmology and their potential implications for the emergence of life in the universe. In particular, I discuss the requirements for carbon-based life, anthropic considerations with respect to the nature of…
Started approximately in the late 1980s, exoplanetology has up to now unveiled the main gross bulk characteristics of planets and planetary systems. In the future it will benefit from more and more large telescopes and advanced space…
The search for extrasolar planets in the past decades has shown that planets abound in the Solar neighborhood. While we are still missing an Earth twin, the forthcoming space missions and ground-based instrumentation are already driven to…
Humanity has wondered whether we are alone for millennia. The discovery of life elsewhere in the Universe, particularly intelligent life, would have profound effects, comparable to those of recognizing that the Earth is not the center of…
The past fifty years have been an epoch of impressive progress in the field of astronomical technology. Practically all the technical tools, which we use today, have been developed during that time span. While the first half of this period…
The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our…
In support of the National Acadamies' Exoplanet Science Strategy, this whitepaper outlines key technology challenges for studying the diversity of worlds in the Galaxy and in searching for habitable planets. Observations of habitable…
Surprisingly, the question "Is there Life in the Universe outside Earth?" has been raised, in rational terms, almost only in the western literature throughout the ages. In a first part I justify this statement. Then I try to develop an…
The search for life on extrasolar planets is based on the assumption that one can screen extrasolar planets for habitability spectroscopically. The first space born instruments able to detect as well as characterize extrasolar planets,…
The intuition suggested by the Drake equation implies that technology should be less prevalent than biology in the galaxy. However, it has been appreciated for decades in the SETI community that technosignatures could be more abundant,…
Exoplanet hunting efforts have revealed the prevalence of exotic worlds with diverse properties, including Earth-sized bodies, which has fueled our endeavor to search for life beyond the Solar System. Accumulating experiences in…
Exploring the Universe is one of the great unifying themes of humanity. Part of this endeavour is the search for extraterrestrial life. But how likely is it that we will find life, or that if we do it will be similar to ourselves? And…
Astrobiology is a scientific discipline that studies life in the Universe. We call it a discipline and not a science because some authors have cast doubts over its epistemological status by calling it 'a science without an object of study'.…
Mars exploration motivates the search for extraterrestrial life, the development of space technologies, and the design of human missions and habitations. Here we seek new insights and pose unresolved questions relating to the natural…
The discovery of planets orbiting stars other than the Sun has accelerated over the past decade, and this trend will continue as new space- and ground-based observatories employ next-generation instrumentation to search the skies for…
A central need in the field of astrobiology is generalized perspectives on life that make it possible to differentiate abiotic and biotic chemical systems. A key component of many past and future astrobiological measurements is the…
Recently, many Earth-sized planets have been discovered around stars other than the Sun that might possess appropriate conditions for life. The development of theoretical methods for assessing the putative habitability of these worlds is of…
One of the most interesting unsolved questions in science today is the question of life on other planets. At the present time it is safe to say that we do not have much of an idea as to whether life is common or exceedingly rare in the…
When we try to search for extraterrestrial life and intelligence, we have to follow some guidelines. The first step is to clarify what is to be meant by "Life" and "intelligence", i.e. an attempt to define these words. The word "definition"…