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Persistent homology provides a robust methodology to infer topological structures from point cloud data. Here we explore the persistent homology of point clouds embedded into a probabilistic setting, exploiting the theory of point…

Probability · Mathematics 2023-08-07 Daniel Spitz , Anna Wienhard

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

Aqueous solubility and partition coefficient are important physical properties of small molecules. Accurate theoretical prediction of aqueous solubility and partition coefficient plays an important role in drug design and discovery. The…

Quantitative Methods · Quantitative Biology 2018-01-08 Kedi Wu , Zhixiong Zhao , Renxiao Wang , Guo-Wei Wei

A multicomplex structure is defined from an ordered lattice of multigraphs. This structure will help us to observe the features of Persistent Homology in this context, its interaction with the ordering and the repercussions of the process…

Algebraic Topology · Mathematics 2025-02-05 Joaquin Diaz Boils

This article introduces an algorithm to compute the persistent homology of a filtered complex with various coefficient fields in a single matrix reduction. The algorithm is output-sensitive in the total number of distinct persistent…

Computational Geometry · Computer Science 2020-01-10 Jean-Daniel Boissonnat , Clément Maria

Persistent homology (PH) has been widely applied to graph data to extract topological features. However, little attention has been paid to how different distance functions on a graph affect the resulting persistence barcodes and their…

Algebraic Topology · Mathematics 2026-02-17 Eunwoo Heo , Byeongchan Choi , Jae-Hun Jung

Protein-ligand binding is a fundamental biological process that is paramount to many other biological processes, such as signal transduction, metabolic pathways, enzyme construction, cell secretion, gene expression, etc. Accurate prediction…

Quantitative Methods · Quantitative Biology 2017-04-03 Zixuan Cang , Guo-Wei Wei

Characterizing the structural properties of neural networks is crucial yet poorly understood, and there are no well-established similarity measures between networks. In this work, we observe that neural networks can be represented as…

Machine Learning · Computer Science 2021-06-01 David Pérez-Fernández , Asier Gutiérrez-Fandiño , Jordi Armengol-Estapé , Marta Villegas

Persistent homology is a tool from Topological Data Analysis (TDA) used to summarize the topology underlying data. It can be conveniently represented through persistence diagrams. Observing a noisy signal, common strategies to infer its…

Statistics Theory · Mathematics 2024-08-28 Hugo Henneuse

Topological data analysis (TDA) uncovers crucial properties of objects in medical imaging. Methods based on persistent homology have demonstrated their advantages in capturing topological features that traditional deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Yanfan Zhu , Yash Singh , Khaled Younis , Shunxing Bao , Yuankai Huo

To analyze the topological properties of the given discrete data, one needs to consider a continuous transform called filtration. Persistent homology serves as a tool to track changes of homology in the filtration. The outcome of the…

Optimization and Control · Mathematics 2024-10-08 Keunsu Kim , Jae-Hun Jung

Topological data analysis (TDA) is a rising branch in modern applied mathematics. It extracts topological structures as features of a given space and uses these features to analyze digital data. Persistent homology, one of the central tools…

Algebraic Topology · Mathematics 2025-05-26 Chuan-Shen Hu

In this note we study some properties of topological entropy for non-compact non-metrizable spaces. We prove that if a uniformly continuous self-map $f$ of a uniform space has topological shadowing property then the map $f$ has positive…

Dynamical Systems · Mathematics 2016-11-30 Seyyed Alireza Ahmadi

Understanding and predicting thermal transport in disordered materials remains a significant challenge due to the absence of periodicity and the complex nature of medium-range structural motifs. In this work, we investigate amorphous…

Materials Science · Physics 2025-12-16 Kosuke Yamazaki , Takuma Shiga , Kumpei Shiraishi , Emi Minamitani

Persistent topological Laplacians constitute a new class of tools in topological data analysis (TDA). They are motivated by the necessity to address challenges encountered in persistent homology when handling complex data. These Laplacians…

Algebraic Topology · Mathematics 2024-12-12 Xiaoqi Wei , Guo-Wei Wei

In this work, we introduce persistent homology for the analysis of cryo-electron microscopy (cryo-EM) density maps. We identify the topological fingerprint or topological signature of noise, which is widespread in cryo-EM data. For low…

Biomolecules · Quantitative Biology 2014-12-09 Kelin Xia , Guo-Wei Wei

We develop information-theoretic measures of spatial structure and pattern in more than one dimension. As is well known, the entropy density of a two-dimensional configuration can be efficiently and accurately estimated via a converging…

Statistical Mechanics · Physics 2009-11-07 David P. Feldman , James P. Crutchfield

In this article we propose a novel approach for comparing the persistent homology representations of two spaces (filtrations). Commonly used methods are based on numerical summaries such as persistence diagrams and persistence landscapes,…

Machine Learning · Computer Science 2021-01-05 Yohai Reani , Omer Bobrowski

In this note a notion of generalized topological entropy for arbitrary subsets of the space of all sequences in a compact topological space is introduced. It is shown that for a continuous map on a compact space the generalized topological…

Dynamical Systems · Mathematics 2024-10-29 Maysam Maysami Sadr , Mina Shahrestani

Topological data analysis provides a collection of tools to encapsulate and summarize the shape of data. Currently it is mainly restricted to \emph{mapper algorithm} and \emph{persistent homology}. In this paper we introduce new…

Algebraic Topology · Mathematics 2019-01-23 Paweł Dłotko
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