Related papers: Cryo-CARE: Content-Aware Image Restoration for Cry…

Cryo-electron microscopy (EM) single particle reconstruction is an entirely general technique for 3D structure determination of macromolecular complexes. However, because the images are taken at low electron dose, it is extremely hard to…

Image denoising is a fundamental task in computer vision. While prevailing deep learning-based supervised and self-supervised methods have excelled in eliminating in-distribution noise, their susceptibility to out-of-distribution (OOD)…

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Recent studies on learning-based image denoising have achieved promising performance on various noise reduction tasks. Most of these deep denoisers are trained either under the supervision of clean references, or unsupervised on synthetic…

When capturing and storing images, devices inevitably introduce noise. Reducing this noise is a critical task called image denoising. Deep learning has become the de facto method for image denoising, especially with the emergence of…

Cryo-Electron Tomography (cryo-ET) is a 3D imaging technology that enables the visualization of subcellular structures in situ at near-atomic resolution. Cellular cryo-ET images help in resolving the structures of macromolecules and…

In recent years, deep learning-based image compression, particularly through generative models, has emerged as a pivotal area of research. Despite significant advancements, challenges such as diminished sharpness and quality in…

We leverage deep learning techniques to jointly denoise and super-resolve biomedical images acquired with fluorescence microscopy. We develop a deep learning algorithm based on the networks and method described in the recent W2S paper to…

Recently, several discriminative learning approaches have been proposed for effective image restoration, achieving convincing trade-off between image quality and computational efficiency. However, these methods require separate training for…

Single-particle cryo-electron microscopy (cryo-EM) is an emerging imaging modality capable of visualizing proteins and macro-molecular complexes at near-atomic resolution. The low electron-doses used to prevent sample radiation damage,…

Cryo-electron microscopy (cryo-EM) is an indispensable technique for determining the 3D structures of dynamic biomolecular complexes. While typically applied to image a single molecular species, cryo-EM has the potential for structure…

Different tasks in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM) require enhancing the quality of the highly noisy raw images. To this end, we develop an efficient algorithm for signal enhancement of…

In this work, we address the limitations of denoising diffusion models (DDMs) in image restoration tasks, particularly the shape and color distortions that can compromise image quality. While DDMs have demonstrated a promising performance…

Compressive sensing is a method to recover the original image from undersampled measurements. In order to overcome the ill-posedness of this inverse problem, image priors are used such as sparsity in the wavelet domain, minimum…

Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream structural biology techniques because of its ability to determine high-resolution structures of dynamic bio-molecules. However, cryo-EM data acquisition…

In machine learning approach to image denoising a network is trained to recover a clean image from a noisy one. In this paper a novel structure is proposed based on training multiple specialized networks as opposed to existing structures…

Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…

In this study, we propose a simple and effective fine-tuning algorithm called "restore-from-restored", which can greatly enhance the performance of fully pre-trained image denoising networks. Many supervised denoising approaches can produce…

Cryogenic electron microscopy (cryo-EM) has become an enabling technology in drug discovery and in understanding molecular bases of disease by producing near-atomic resolution (less than 0.4 nm) 3D reconstructions of biological…

We propose to leverage denoising autoencoder networks as priors to address image restoration problems. We build on the key observation that the output of an optimal denoising autoencoder is a local mean of the true data density, and the…