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CT Perfusion (CTP) imaging has gained importance in the diagnosis of acute stroke. Conventional perfusion analysis performs a deconvolution of the measurements and thresholds the perfusion parameters to determine the tissue status. We…

Perfusion imaging is crucial in acute ischemic stroke for quantifying the salvageable penumbra and irreversibly damaged core lesions. As such, it helps clinicians to decide on the optimal reperfusion treatment. In perfusion CT imaging,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Ezequiel de la Rosa , Diana M. Sima , Bjoern Menze , Jan S. Kirschke , David Robben

Purpose: In this study we investigate whether a Convolutional Neural Network (CNN) can generate clinically relevant parametric maps from CT perfusion data in a clinical setting of patients with acute ischemic stroke. Methods: Training of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-18 Umberto A. Gava , Federico D'Agata , Enzo Tartaglione , Marco Grangetto , Francesca Bertolino , Ambra Santonocito , Edwin Bennink , Mauro Bergui

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is widely used to evaluate acute ischemic stroke to distinguish salvageable tissue and infarct core. For this purpose, traditional methods employ deconvolution techniques,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Anbo Cao , Pin-Yu Le , Zhonghui Qie , Haseeb Hassan , Yingwei Guo , Asim Zaman , Jiaxi Lu , Xueqiang Zeng , Huihui Yang , Xiaoqiang Miao , Taiyu Han , Guangtao Huang , Yan Kang , Yu Luo , Jia Guo

Perfusion analysis computes blood flow parameters (blood volume, blood flow, mean transit time) from the observed flow of contrast agent, passing through the patient's vascular system. Perfusion deconvolution has been widely accepted as the…

Computational Engineering, Finance, and Science · Computer Science 2010-06-02 Oleg Pianykh

Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…

Medical Physics · Physics 2020-05-21 Dufan Wu , Hui Ren , Quanzheng Li

In this work, we present a novel convolutional neural net- work based method for perfusion map generation in dynamic suscepti- bility contrast-enhanced perfusion imaging. The proposed architecture is trained end-to-end and solely relies on…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Andreas Hess , Raphael Meier , Johannes Kaesmacher , Simon Jung , Fabien Scalzo , David Liebeskind , Roland Wiest , Richard McKinley

Characterization of quantum objects, being them states, processes, or measurements, complemented by previous knowledge about them is a valuable approach, especially as it leads to routine procedures for real-life components. To this end,…

Quantum Physics · Physics 2023-06-28 Massimiliano Guarneri , Ilaria Gianani , Marco Barbieri , Andrea Chiuri

Stroke is the second most common cause of death in developed countries, where rapid clinical intervention can have a major impact on a patient's life. To perform the revascularization procedure, the decision making of physicians considers…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Adriano Pinto , Sergio Pereira , Raphael Meier , Victor Alves , Roland Wiest , Carlos A. Silva , Mauricio Reyes

DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…

Quantitative Methods · Quantitative Biology 2025-10-17 Pierre Fayolle , Alexandre Bône , Noëlie Debs , Mathieu Naudin , Pascal Bourdon , Remy Guillevin , David Helbert

To shorten the door-to-puncture time for better treating patients with acute ischemic stroke, it is highly desired to obtain quantitative cerebral perfusion images using C-arm cone-beam computed tomography (CBCT) equipped in the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Haotian Zhao , Ruifeng Chen , Jing Yan , Juan Feng , Jun Xiang , Yang Chen , Dong Liang , Yinsheng Li

Perfusion imaging is the current gold standard for acute ischemic stroke analysis. It allows quantification of the salvageable and non-salvageable tissue regions (penumbra and core areas respectively). In clinical settings, the singular…

Image and Video Processing · Electrical Eng. & Systems 2021-04-01 Ezequiel de la Rosa , David Robben , Diana M. Sima , Jan S. Kirschke , Bjoern Menze

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz

Diffusion magnetic resonance imaging is sensitive to the microstructural properties of brain tissue. However, estimating clinically and scientifically relevant microstructural properties from the measured signals remains a highly…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Leevi Kerkelä , Kiran Seunarine , Filip Szczepankiewicz , Chris A. Clark

A fully-convolutional neural-network model is used to predict the streamwise velocity fields at several wall-normal locations by taking as input the streamwise and spanwise wall-shear-stress planes in a turbulent open channel flow. The…

Fluid Dynamics · Physics 2020-08-26 L. Guastoni , M. P. Encinar , P. Schlatter , H. Azizpour , R. Vinuesa

Accurate prediction of cerebral blood flow is essential for the diagnosis and treatment of cerebrovascular diseases. Traditional computational methods, however, often incur significant computational costs, limiting their practicality in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Seungyeon Kim , Wheesung Lee , Sung-Ho Ahn , Do-Eun Lee , Tae-Rin Lee

Convolution and deconvolution are essential techniques in various fields, notably in medical imaging, where they play a crucial role in analyzing dynamic processes such as blood flow. This paper explores the convolution and deconvolution of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ishmael N. Amartey , Andreas A. Linninger , Thomas Ventimiglia

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Scene flow estimation is an essential ingredient for a variety of real-world applications, especially for autonomous agents, such as self-driving cars and robots. While recent scene flow estimation approaches achieve a reasonable accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Yushan Zhang , Bastian Wandt , Maria Magnusson , Michael Felsberg

Purpose: To develop biophysics-based method for estimating perfusion Q from arterial spin labeling (ASL) images using deep learning. Methods: A 3D U-Net (QTMnet) was trained to estimate perfusion from 4D tracer propagation images. The…

Quantitative Methods · Quantitative Biology 2023-11-20 Renjiu Hu , Qihao Zhang , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang
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