Related papers: Receptor crosstalk improves concentration sensing …
The binding between proteins and ligands plays a crucial role in the realm of drug discovery. Previous deep learning approaches have shown promising results over traditional computationally intensive methods, but resulting in poor…
Text alignment finds application in tasks such as citation recommendation and plagiarism detection. Existing alignment methods operate at a single, predefined level and cannot learn to align texts at, for example, sentence and document…
We consider a basic communication and sensing setup comprising a transmitter, a receiver and a sensor. The transmitter sends an encoded sequence to the receiver through a discrete memoryless channel, and the receiver is interested in…
Eukaryotic cells perform chemotaxis by determining the direction of chemical gradients based on stochastic sensing of concentrations at the cell surface. To examine the efficiency of this process, previous studies have investigated the…
Cells rely on the ability to sense and respond to small spatial differences in chemoattractant concentrations for survival. There is growing evidence that this is accomplished by setting the signaling system near the threshold for…
Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains…
Molecular Communications (MC) is a bio-inspired communication technique that uses molecules to encode and transfer information. Many efforts have been focused on developing new modulation techniques for MC by exploiting distinguishable…
Identification of cognates across related languages is one of the primary problems in historical linguistics. Automated cognate identification is helpful for several downstream tasks including identifying sound correspondences,…
The molecular recognition of T-cell receptors is the hallmark of the adaptive immunity. Given the finiteness of the T-cell repertoire, individual T-cell receptors are necessary to be cross-reactive to multiple antigenic peptides. In this…
Collective cell migration in response to a chemical cue occurs in many biological processes such as morphogenesis and cancer metastasis. Clusters of migratory cells in these systems are capable of responding to gradients of less than 1%…
Signalling pathways are abstractions that help life scientists structure the coordination of cellular activity. Cross-talk between pathways accounts for many of the complex behaviours exhibited by signalling pathways and is often critical…
Multi-task learning (MTL) has been widely used in recommender systems, wherein predicting each type of user feedback on items (e.g, click, purchase) are treated as individual tasks and jointly trained with a unified model. Our key…
Accurate prediction of protein-ligand binding affinity is critical for drug discovery. While recent deep learning approaches have demonstrated promising results, they often rely solely on structural features of proteins and ligands,…
In this paper, diffusion-based molecular commu- nication with ligand receptor receivers is studied. Information messages are assumed to be encoded via variations of the con- centration of molecules. The randomness in the ligand reception…
Recent studies reported complex post-transcriptional interplay among targets of a common pool of microRNAs, a class of small non-coding downregulators of gene expression. Behaving as microRNA-sponges, distinct RNA species may compete for…
Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent…
In this paper, we address task-oriented (or goal-oriented) communications where an encoder at the transmitter learns compressed latent representations of data, which are then transmitted over a wireless channel. At the receiver, a decoder…
Gradient sensing underlies important biological processes including morphogenesis, polarization, and cell migration. The precision of gradient sensing increases with the length of a detector (a cell or group of cells) in the gradient…
Multitask learning (MTL) has become prominent for its ability to predict multiple tasks jointly, achieving better per-task performance with fewer parameters than single-task learning. Recently, decoder-focused architectures have…
Semantic communications conveys task-relevant meaning rather than focusing solely on message reconstruction, improving bandwidth efficiency and robustness for next-generation wireless systems. However, learned semantic representations can…