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We introduce a simple multiplicative model to describe the temporal behavior and the ultimate outcome of an epidemic. Our model accounts, in a minimalist way, for the competing influences of imposing public-health restrictions when the…

Physics and Society · Physics 2025-01-14 P. L. Krapivsky , S. Redner

To face pandemics like the one caused by COVID-19, resources such as personal protection equipment (PPE) are needed to reduce the infection rate and protect those in close contact with patients (Heymann and Shindo, 2020; Klompas et al.,…

Systems and Control · Electrical Eng. & Systems 2022-01-28 G. K. den Nijs , J. Edivaldo , B. D. L. Chatel , J. F. Uleman , M. Olde Rikkert , H. Wertheim , R. Quax

In Part 1, we introduced a stochastic model of an infectious disease, based on the BDI (birth and death with immigration) process. We showed that random processes defined by this model can capture the essence of the stochastic, often…

Populations and Evolution · Quantitative Biology 2021-01-28 Hisashi Kobayashi

Metapopulation models are commonly used in ecology, evolution, and epidemiology. These models usually entail homogeneity assumptions within patches and study networks of migration between patches to generate insights into conservation of…

Populations and Evolution · Quantitative Biology 2025-06-06 Diepreye Ayabina , Hasan Sevil , Adam Kleczkowski , M. Gabriela M. Gomes

A pandemic poses particular challenges to decision-making because of the need to continuously adapt decisions to rapidly changing evidence and available data. For example, which countermeasures are appropriate at a particular stage of the…

We propose a model of the immunity to a cyclical epidemic disease taking account not only of seasonal boosts during the infectious season, but also of residual immunity remaining from one season to the next. The focus is on the exponential…

Populations and Evolution · Quantitative Biology 2024-04-22 Siyu Chen , David Sankoff

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such…

Methodology · Statistics 2026-01-27 Heejong Bong , Valérie Ventura , Larry Wasserman

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

Quantitative Methods · Quantitative Biology 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

Epidemic control frequently relies on adjusting interventions based on prevalence. But designing such policies is a highly non-trivial problem due to uncertain intervention effects, costs and the difficulty of quantifying key transmission…

Populations and Evolution · Quantitative Biology 2025-09-16 Giovanni Pugliese Carratelli , Xiaodong Cheng , Kris V. Parag , Ioannis Lestas

This work aims to provide an approach to the macroscopic modeling and simulation of pedestrian flow, coupled with contagion spreading, towards numerical investigation of the effect of certain, macro-control measures on epidemics transport…

Populations and Evolution · Quantitative Biology 2024-11-26 A. I. Delis , N. Bekiaris-Liberis

This work presents a model combining the simplest communicable and non-communicable disease models. The latter is, by far, the leading cause of sickness and death in the World, and introduces basal heterogeneity in populations where…

Populations and Evolution · Quantitative Biology 2023-03-29 M. Marvá , E. Venturino , M. C. Vera

Measures of wealth and production have been found to scale superlinearly with the population of a city. Therefore, it makes economic sense for humans to congregate together in dense settlements. A recent model of population dynamics showed…

Physics and Society · Physics 2016-12-28 James PL Tan

Social contact networks underlying epidemic processes in humans and animals are highly dynamic. The spreading of infections on such temporal networks can differ dramatically from spreading on static networks. We theoretically investigate…

Physics and Society · Physics 2017-09-13 Tomokatsu Onaga , James P. Gleeson , Naoki Masuda

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

Physics and Society · Physics 2020-05-04 Harshad Khadilkar , Tanuja Ganu , Deva P Seetharam

The shape of an epidemic wave in simple epidemic models applies to a homogeneous distribution of infected people in the population. In large inhomogeneous systems, at country-scale for instance, the wave shape is similar except for the…

Chemical Physics · Physics 2022-11-21 L. Vanel

We investigate, at the fundamental level, the questions of `why', `when' and `how' one could or should reach out to poor and vulnerable people to support them in the absence of governmental institutions. We provide a simple and new approach…

General Economics · Economics 2023-07-31 Aziz Guergachi , Javid Hakim