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This paper considers neural representation through the lens of active inference, a normative framework for understanding brain function. It delves into how living organisms employ generative models to minimize the discrepancy between…

Neurons and Cognition · Quantitative Biology 2023-10-24 Giovanni Pezzulo , Leo D'Amato , Francesco Mannella , Matteo Priorelli , Toon Van de Maele , Ivilin Peev Stoianov , Karl Friston

We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel.…

Subcellular Processes · Quantitative Biology 2007-06-06 Jan Gomulkiewicz , Jacek Miekisz , Stanislaw Miekisz

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing…

Other Quantitative Biology · Quantitative Biology 2017-09-15 Maël Montévil , Lucia Speroni , Carlos Sonnenschein , Ana M. Soto

We study a mathematical model of biological neuronal networks composed by any finite number $N \geq 2$ of non necessarily identical cells. The model is a deterministic dynamical system governed by finite-dimensional impulsive differential…

Biological Physics · Physics 2013-11-19 Eleonora Catsigeras

In this article, the notion of a mathematical model in science is attempted to be enlightened from several points of view. In particular, it is shown that mathematical models are introduced differently and used differently in different…

History and Overview · Mathematics 2022-05-25 Inge S. Helland

Symmetries have proven to be important ingredients in the analysis of neural networks. So far their use has mostly been implicit or seemingly coincidental. We undertake a systematic study of the role that symmetry plays. In particular, we…

Machine Learning · Computer Science 2021-04-13 Grzegorz Głuch , Rüdiger Urbanke

Since they became observable, neuron morphologies have been informally compared with biological trees but they are studied by distinct communities, neuroscientists, and ecologists. The apparent structural similarity suggests there may be…

Neurons and Cognition · Quantitative Biology 2023-07-06 Roozbeh Farhoodi , Phil Wilkes , Anirudh M. Natarajan , Samantha Ing-Esteves , Julie L. Lefebvre , Mathias Disney , Konrad P. Kording

Elucidating the neurophysiological mechanisms underlying neural pattern formation remains an outstanding challenge in Computational Neuroscience. In this paper, we address the issue of understanding the emergence of neural patterns by…

Neurons and Cognition · Quantitative Biology 2024-06-04 Gregory Dumont , Carmen Oana Tarniceriu

Model reparametrization, which follows the change-of-variable rule of calculus, is a popular way to improve the training of neural nets. But it can also be problematic since it can induce inconsistencies in, e.g., Hessian-based flatness…

Machine Learning · Computer Science 2023-10-24 Agustinus Kristiadi , Felix Dangel , Philipp Hennig

Mechanistic interpretability aims to break models into meaningful parts; verifying that two such parts implement the same computation is a prerequisite. Existing similarity measures evaluate either empirical behaviour, leaving them blind to…

Machine Learning · Computer Science 2026-05-15 ML Nissen Gonzalez , Melwina Albuquerque , Laurence Wroe , Jacob Meyer Cohen , Logan Riggs Smith , Thomas Dooms

We can define a neural network that can learn to recognize objects in less than 100 lines of code. However, after training, it is characterized by millions of weights that contain the knowledge about many object types across visual scenes.…

Machine Learning · Computer Science 2019-07-16 Timothy P. Lillicrap , Konrad P. Kording

We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a balance between ion channels that…

Neurons and Cognition · Quantitative Biology 2015-06-11 Alessio Franci , Guillaume Drion , Vincent Seutin , Rodolphe Sepulchre

In the brain, the structure of a network of neurons defines how these neurons implement the computations that underlie the mind and the behavior of animals and humans. Provided that we can describe the network of neurons as a graph, we can…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Gustavo Borges Moreno e Mello , Vibeke Devold Valderhaug , Sidney Pontes-Filho , Evi Zouganeli , Ioanna Sandvig , Stefano Nichele

This paper highlights the possibility of creating quantum neural networks that are trained by Grover's Search Algorithm. The purpose of this work is to propose the concept of combining the training process of a neural network, which is…

Quantum Physics · Physics 2021-10-05 Cesar Borisovich Pronin , Andrey Vladimirovich Ostroukh

Despite impressive performance on numerous visual tasks, Convolutional Neural Networks (CNNs) --- unlike brains --- are often highly sensitive to small perturbations of their input, e.g. adversarial noise leading to erroneous decisions. We…

Neuromorphic computing takes inspiration from the brain to create energy efficient hardware for information processing, capable of highly sophisticated tasks. In this article, we make the case that building this new hardware necessitates…

Emerging Technologies · Computer Science 2020-03-26 Danijela Markovic , Alice Mizrahi , Damien Querlioz , Julie Grollier

We describe the operation of a neuronal device which embodies the computational principles of the `paper-and-pencil' machine envisioned by Alan Turing. The network is based on principles of cortical organization. We develop a plausible…

Neurons and Cognition · Quantitative Biology 2013-12-24 Ariel D Zylberberg , Luciano Paz , Pieter R Roelfsema , Stanislas Dehaene , Mariano Sigman

Artificial neural networks (ANNs), inspired by the interconnection of real neurons, have achieved unprecedented success in various fields such as computer vision and natural language processing. Recently, a novel mathematical ANN model,…

Neural and Evolutionary Computing · Computer Science 2023-09-15 Yu Ding , Jun Yu , Chunzhi Gu , Shangce Gao , Chao Zhang

Neural Networks (NN) has been used in many areas with great success. When a NN's structure (Model) is given, during the training steps, the parameters of the model are determined using an appropriate criterion and an optimization algorithm…

Machine Learning · Computer Science 2024-08-15 Ali Mohammad-Djafari , Ning Chu , Li Wang , Caifang Cai , Liang Yu