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Several stochastic processes modeling molecular motors on a linear track are given by random walks (not necessarily Markovian) on quasi 1d lattices and share a common regenerative structure. Analyzing this abstract common structure, we…

Probability · Mathematics 2014-05-08 Alessandra Faggionato , Vittoria Silvestri

In this paper, we propose a new workflow to analyze macrophage motion during wound healing. These immune cells are attracted to the wound after an injury and they move showing both directional and random motion. Thus, first, we smooth the…

Numerical Analysis · Mathematics 2025-03-14 Giulia Lupi , Seol Ah Park , Martin Ambroz , Resul Ozbilgic , Mai Nguyen Chi , Georges Lutfalla , Karol Mikula

Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

Biological Physics · Physics 2023-10-10 David B. Brückner , Chase P. Broedersz

We study a minimal model of a crawling eukaryotic cell with a chemical polarity controlled by a reaction-diffusion mechanism describing Rho GTPase dynamics. The size, shape, and speed of the cell emerge from the combination of the chemical…

Biological Physics · Physics 2017-01-11 Brian A. Camley , Yanxiang Zhao , Bo Li , Herbert Levine , Wouter-Jan Rappel

Consider a supercritical branching random walk on the real line. The consistent maximal displacement is the smallest of the distances between the trajectories followed by individuals at the $n$th generation and the boundary of the process.…

Probability · Mathematics 2019-05-21 Bastien Mallein

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

We develop a continuous time random walk (CTRW) approach for the evolution of Lagrangian velocities in steady heterogeneous flows based on a stochastic relaxation process for the streamwise particle velocities. This approach describes…

Fluid Dynamics · Physics 2016-11-30 Marco Dentz , Peter K. Kang , Alessandro Comolli , Tanguy Le Borgne , Daniel R. Lester

In many physical, social or economical phenomena we observe changes of a studied quantity only in discrete, irregularly distributed points in time. The stochastic process used by physicists to describe this kind of variables is the…

Statistical Finance · Quantitative Finance 2020-04-14 Jarosław Klamut , Tomasz Gubiec

Constructing physical models of living cells and tissues is an extremely challenging task because of the high complexities of both intra- and intercellular processes. In addition, the force that a single cell generates vanishes in total due…

Soft Condensed Matter · Physics 2019-05-09 Mitsusuke Tarama , Kenji Mori , Ryoichi Yamamoto

We consider the dynamics of a separable Continuous Time Random Walk (CTRW) when the random walker is biased by a velocity field in a uniformly growing domain. Concrete examples for such domains include growing biological cells or lipid…

Statistical Mechanics · Physics 2020-08-26 F. Le Vot , E. Abad , R. Metzler , S. B. Yuste

We consider random walks on quasi one dimensional lattices, as introduced in \cite{FS}. This mathematical setting covers a large class of discrete kinetic models for non-cooperative molecular motors on periodic tracks. We derive general…

Probability · Mathematics 2015-06-19 Alessandra Faggionato , Vittoria Silvestri

The combination of protrusions and retractions in the movement of polarized cells leads to understand the effect of possible synchronisation between the two ends of the cells. This synchronisation, in turn, could lead to different dynamics…

Cell Behavior · Quantitative Biology 2021-09-21 Gissell Estrada-Rodriguez , Benoit Perthame

Recent progresses in single particle tracking have shown evidences of non-Gaussian distribution of displacements in living cells, both near the cellular membrane and inside the cytoskeleton. A similar behavior has also been observed in…

Biological Physics · Physics 2019-05-30 Yann Lanoiselée , Denis S. Grebenkov

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

Cell migration is fundamental to development, tissue organization, immune response, and disease progression. Amoeboid motility is distinguished by rapid motion and strongly fluctuating cell shapes, reflecting the intrinsically nonlinear…

Soft Condensed Matter · Physics 2026-05-19 Winfried Schmidt , Chaouqi Misbah , Alexander Farutin

Cell migration is a fundamental process for life and is highly dependent on the dynamical and mechanical properties of the cytoskeleton. Intensive physical and biochemical crosstalk between actin, microtubules, and intermediate filaments…

Biological Physics · Physics 2024-01-17 James P. Conboy , Irene Istúriz Petitjean , Anouk van der Net , Gijsje H. Koenderink

Localization is a characteristic phenomenon of space-inhomogeneous quantum walks in one dimension, where particles remain localized around their initial position. The existence of eigenvalues of time evolution operators is a necessary and…

Mathematical Physics · Physics 2022-10-25 Chusei Kiumi , Kei Saito

Liquid-liquid phase separation has emerged as a fundamental mechanism underlying intracellular organization, with evidence for it being reported in numerous different systems. However, there is a growing concern regarding the lack of…

Soft Condensed Matter · Physics 2022-12-09 Mrityunjay Kothari , Tal Cohen

A novel random walk based model for inter-core cross-talk (IC-XT) characterization of multi-core fibres capable of accurately representing both time-domain distribution and frequency-domain representation of experimental IC-XT has been…

Signal Processing · Electrical Eng. & Systems 2020-09-01 Alessandro Ottino , Hui Yuan , Yunnuo Xu , Eric Sillekens , Georgios Zervas