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The ability to automatically detect certain types of cells or cellular subunits in microscopy images is of significant interest to a wide range of biomedical research and clinical practices. Cell detection methods have evolved from…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Yao Xue , Nilanjan Ray

In this work, we explore the intersection of sparse coding theory and deep learning to enhance our understanding of feature extraction capabilities in advanced neural network architectures. We begin by introducing a novel class of Deep…

Machine Learning · Computer Science 2025-12-05 Jianfei Li , Han Feng , Ding-Xuan Zhou

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Deep learning, e.g., convolutional neural networks (CNNs), has achieved great success in image processing and computer vision especially in high level vision applications such as recognition and understanding. However, it is rarely used to…

Computer Vision and Pattern Recognition · Computer Science 2017-08-03 Feng Jiang , Wen Tao , Shaohui Liu , Jie Ren , Xun Guo , Debin Zhao

Cell detection in microscopy images is important to study how cells move and interact with their environment. Most recent deep learning-based methods for cell detection use convolutional neural networks (CNNs). However, inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Royden Wagner , Karl Rohr

Purpose: The aim of this work is to demonstrate that convolutional neural networks (CNN) can be applied to extremely sparse image libraries by subdivision of the original image datasets. Methods: Image datasets from a conventional digital…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Johan P. Boetker

Cell segmentation and tracking in microscopy images are of great significance to new discoveries in biology and medicine. In this study, we propose a novel approach to combine cell segmentation and cell tracking into a unified end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Yuqian Chen , Yang Song , Chaoyi Zhang , Fan Zhang , Lauren O'Donnell , Wojciech Chrzanowski , Weidong Cai

Deep Convolutional Neural Networks (CNNs) for image classification successively alternate convolutions and downsampling operations, such as pooling layers or strided convolutions, resulting in lower resolution features the deeper the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-29 Ioannis Vezakis , Antonios Vezakis , Sofia Gourtsoyianni , Vassilis Koutoulidis , George K. Matsopoulos , Dimitrios Koutsouris

Compressive sensing (CS), aiming to reconstruct an image/signal from a small set of random measurements has attracted considerable attentions in recent years. Due to the high dimensionality of images, previous CS methods mainly work on…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Xiaotong Lu , Weisheng Dong , Peiyao Wang , Guangming Shi , Xuemei Xie

We present an approach to learn a dense pixel-wise labeling from image-level tags. Each image-level tag imposes constraints on the output labeling of a Convolutional Neural Network (CNN) classifier. We propose Constrained CNN (CCNN), a…

Computer Vision and Pattern Recognition · Computer Science 2015-10-20 Deepak Pathak , Philipp Krähenbühl , Trevor Darrell

We propose a weakly-supervised cell tracking method that can train a convolutional neural network (CNN) by using only the annotation of "cell detection" (i.e., the coordinates of cell positions) without association information, in which…

Computer Vision and Pattern Recognition · Computer Science 2020-07-31 Kazuya Nishimura , Junya Hayashida , Chenyang Wang , Dai Fei Elmer Ker , Ryoma Bise

One impressive advantage of convolutional neural networks (CNNs) is their ability to automatically learn feature representation from raw pixels, eliminating the need for hand-designed procedures. However, recent methods for single image…

Computer Vision and Pattern Recognition · Computer Science 2016-07-27 Yifan Wang , Lijun Wang , Hongyu Wang , Peihua Li

Accurately counting cells in microscopic images is important for medical diagnoses and biological studies, but manual cell counting is very tedious, time-consuming, and prone to subjective errors, and automatic counting can be less accurate…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Mark Anastasio , Hua Li

Convolutional neural networks (CNNs) for biomedical image analysis are often of very large size, resulting in high memory requirement and high latency of operations. Searching for an acceptable compressed representation of the base CNN for…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Suraj Mishra , Peixian Liang , Adam Czajka , Danny Z. Chen , X. Sharon Hu

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

Automatic cell detection in histology images is a challenging task due to varying size, shape and features of cells and stain variations across a large cohort. Conventional deep learning methods regress the probability of each pixel…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Shan E Ahmed Raza , Khalid AbdulJabbar , Mariam Jamal-Hanjani , Selvaraju Veeriah , John Le Quesne , Charles Swanton , Yinyin Yuan

Reconstruction tasks in computer vision aim fundamentally to recover an undetermined signal from a set of noisy measurements. Examples include super-resolution, image denoising, and non-rigid structure from motion, all of which have seen…

Computer Vision and Pattern Recognition · Computer Science 2020-04-01 Nathaniel Chodosh , Simon Lucey

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing

Pervasive localization is essential for continuous tracking applications, yet existing solutions face challenges in balancing power consumption and accuracy. GPS, while precise, is impractical for continuous tracking of micro-assets due to…

Systems and Control · Electrical Eng. & Systems 2025-05-12 Aritrik Ghosh , Nakul Garg , Nirupam Roy

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut
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