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Hippocampal place and time cells encode spatial and temporal aspects of experience. Both have the same neural substrate, but have been modeled as having different functions and mechanistic origins, place cells as continuous attractors, and…

Neurons and Cognition · Quantitative Biology 2026-04-02 Qiaorong S. Yu , Zhaoze Wang , Vijay Balasubramanian

Signal transduction, or signal-processing capability, is a fundamental property of nature that manifests universally across systems of different scales -- from quantum behaviour to the biological. This includes the detection of…

Signal Processing · Electrical Eng. & Systems 2023-09-12 Dorje C. Brody , Anthony J. Trewavas

Identifying a temporal pattern of events is a fundamental task of on-line (real-time) verification. We present efficient schemes for on-line monitoring of events for identifying desired/undesired patterns of events. The schemes use…

Data Structures and Algorithms · Computer Science 2015-05-28 Shlomi Dolev , Jonathan Goldfeld , Rami Puzis

The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple…

Molecular Networks · Quantitative Biology 2007-05-23 Sandeep Krishna , Anna M. C. Andersson , Szabolcs Semsey , Kim Sneppen

Many-body quantum systems, under suitable conditions, exhibit time-translation symmetry breaking and settle in a discrete time crystalline (DTC) phase -- an out-of-equilibrium quantum phase of matter. The defining feature of DTC is a robust…

Quantum Physics · Physics 2025-11-14 Gourab Das , Saptarshi Saha , Rangeet Bhattacharyya

Circadian clocks are the central timekeepers of life, allowing cells to anticipate changes between day and night. Experiments in recent years have revealed that circadian clocks can be highly stable, raising the question how reliably they…

Molecular Networks · Quantitative Biology 2016-06-22 Michele Monti , Pieter Rein ten Wolde

Studies of insect olfactory processing indicate that odors are represented by rich spatio-temporal patterns of neural activity. These patterns are very difficult to predict a priori, yet they are stimulus specific and reliable upon repeated…

Neurons and Cognition · Quantitative Biology 2007-05-23 M. I. Rabinovich , R. Huerta , A. Volkovskii , Henry D. I. Abarbanel , G. Laurent

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

Biomolecules · Quantitative Biology 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

Frequency discrimination is a fundamental task of the auditory system. The mammalian inner ear, or cochlea, provides a place code in which different frequencies are detected at different spatial locations. However, a temporal code based on…

Neurons and Cognition · Quantitative Biology 2015-06-05 Tobias Reichenbach , A. J. Hudspeth

Periodic patterns in dynamical behaviours of biological models described by simple form differential delay equations are studied. Mathematical models are given by a class of scalar delay differential equations with a multiplicative time…

Dynamical Systems · Mathematics 2025-10-01 A. Ivanov , S. Shelyag

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

Neuronal circuits of the cerebral cortex are the structural basis of mammalian cognition. The same qualitative components and connectivity motifs are repeated across functionally specialized cortical areas and mammalian species, suggesting…

Neurons and Cognition · Quantitative Biology 2025-07-04 Arno Granier , Katharina A Wilmes , Mihai A Petrovici , Walter Senn

Analyzing temporal developments is crucial for the accurate prognosis of many medical conditions. Temporal changes that occur over short time scales are key to assessing the health of physiological functions, such as the cardiac cycle.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Chengzhi Shen , Martin J. Menten , Hrvoje Bogunović , Ursula Schmidt-Erfurth , Hendrik Scholl , Sobha Sivaprasad , Andrew Lotery , Daniel Rueckert , Paul Hager , Robbie Holland

We have investigated the role that different connectivity regimes play on the dynamics of a network of Hodgkin-Huxley neurons by computer simulations. The different connectivity topologies exhibit the following features: random connectivity…

Disordered Systems and Neural Networks · Physics 2025-03-24 Luis F. Lago-Fernandez , Ramon Huerta , Fernando Corbacho , Juan A. Siguenza

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

Neurons and Cognition · Quantitative Biology 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

To successfully navigate chemical gradients, microorganisms need to predict how the ligand concentration changes in space. Due to their limited size, they do not take a spatial derivative over their body length but rather a temporal…

Molecular Networks · Quantitative Biology 2024-02-09 Age J. Tjalma , Pieter Rein ten Wolde

The intermittency of solar and wind power can be addressed by integrating them with Solid Oxide Cells (SOCs). This study delves into the transient characteristics of SOCs and their dependence on dynamic heat and mass transfer processes.…

Fluid Dynamics · Physics 2024-05-31 Zhaojian Liang , Jingyi Wang , Liang An , Yang Wang , Meng Ni , Mengying Li

Most diffusion based molecular channels suffer from low information capacity due to the structure of the diffusion environment. To address this issue, this paper studies the capacity of the diffusion based molecular communication by…

Information Theory · Computer Science 2020-06-25 Farhad Mirkarimi , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari

Segregation of different cell types is a crucial process for the pattern formation in tissues, in particular during embryogenesis. Since the involved cell interactions are complex and difficult to measure individually in experiments,…

Cell Behavior · Quantitative Biology 2022-09-21 Florian Franke , Sebatian Aland , Hans-Joachim Böhme , Anja Voss-Böhme , Steffen Lange

Molecular communication is a novel approach for data transmission between miniaturized devices, especially in contexts where electrical signals are to be avoided. The communication is based on sending molecules (or other particles) at nano…

Emerging Technologies · Computer Science 2023-08-08 Max Bartunik , Jens Kirchner , Oliver Keszocze
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