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Stronger selection implies faster evolution---that is, the greater the force, the faster the change. This apparently self-evident proposition, however, is derived under the assumption that genetic variation within a population is primarily…

Populations and Evolution · Quantitative Biology 2017-08-18 Masahiko Ueda , Nobuto Takeuchi , Kunihiko Kaneko

The stage of evolution is the population of reproducing individuals. The structure of the population is know to affect the dynamics and outcome of evolutionary processes, but analytical results for generic random structures have been…

Populations and Evolution · Quantitative Biology 2014-07-10 Ben Adlam , Martin A. Nowak

Weak selection, which means a phenotype is slightly advantageous over another, is an important limiting case in evolutionary biology. Recently it has been introduced into evolutionary game theory. In evolutionary game dynamics, the…

Populations and Evolution · Quantitative Biology 2010-10-15 Bin Wu , Philipp M. Altrock , Long Wang , Arne Traulsen

The population structure often impacts evolutionary dynamics. In constant-selection evolutionary dynamics between two types, amplifiers of selection are networks that promote the fitter mutant to take over the entire population, and…

Physics and Society · Physics 2024-09-04 Jnanajyoti Bhaumik , Naoki Masuda

We investigate the statistics of the time taken for a system driven by recruitment to reach fixation. Our model describes a series of experiments where a population is confronted with two identical options, resulting in the system fixating…

Statistical Mechanics · Physics 2015-01-26 Tommaso Biancalani , Louise Dyson , Alan J. McKane

Population structure and spatial heterogeneity are integral components of evolutionary dynamics, in general, and of evolution of cooperation, in particular. Structure can promote the emergence of cooperation in some populations and suppress…

Populations and Evolution · Quantitative Biology 2017-10-10 Yu-Ting Chen , Alex McAvoy , Martin A. Nowak

In stochastic evolutionary dynamics, the replacement of an existing genotype or cultural trait by a newly introduced mutant is typically characterized by the quantities of fixation probability and fixation time. But in a structured…

Populations and Evolution · Quantitative Biology 2026-05-27 David A. Brewster , Gabor Lippner , Josef Tkadlec , Martin A. Nowak

How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider the time until a…

Populations and Evolution · Quantitative Biology 2010-03-31 Chaitanya S. Gokhale , Yoh Iwasa , Martin A. Nowak , Arne Traulsen

Many mathematical models of evolution assume that all individuals experience the same environment. Here, we study the Moran process in heterogeneous environments. The population is of finite size with two competing types, which are exposed…

Populations and Evolution · Quantitative Biology 2018-12-19 Kamran Kaveh , Alex McAvoy , Martin A. Nowak

A stochastic evolutionary dynamics of two strategies given by 2 x 2 matrix games is studied in finite populations. We focus on stochastic properties of fixation: how a strategy represented by a single individual wins over the entire…

Populations and Evolution · Quantitative Biology 2007-05-23 Tibor Antal , Istvan Scheuring

In large asexual populations, beneficial mutations have to compete with each other for fixation. Here, I derive explicit analytic expressions for the rate of substitution and the mean beneficial effect of fixed mutations, under the…

Populations and Evolution · Quantitative Biology 2007-05-23 Claus O. Wilke

Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have…

Populations and Evolution · Quantitative Biology 2014-07-30 Wes Maciejewski , Gregory J. Puleo

Mutations in a microbial population can increase the frequency of a genotype not only by increasing its exponential growth rate, but also by decreasing its lag time or adjusting the yield (resource efficiency). The contribution of multiple…

Populations and Evolution · Quantitative Biology 2018-02-15 Michael Manhart , Bharat V. Adkar , Eugene I. Shakhnovich

The dynamics of a two-species community of $N$ competing individuals is considered, with an emphasis on the role of environmental variations that affect coherently the fitness of entire populations. The chance of fixation of a mutant…

Populations and Evolution · Quantitative Biology 2018-02-01 Immanuel Meyer , Nadav M. Shnerb

People tend to have their social interactions with members of their own community. Such group-structured interactions can have a profound impact on the behaviors that evolve. Group structure affects the way people cooperate, and how they…

Populations and Evolution · Quantitative Biology 2022-11-09 Yohsuke Murase , Christian Hilbe , Seung Ki Baek

Large sets of genotypes give rise to the same phenotype because phenotypic expression is highly redundant. Accordingly, a population can accept mutations without altering its phenotype, as long as thegenotype mutates into another one on the…

Populations and Evolution · Quantitative Biology 2015-02-18 Susanna Manrubia , José A. Cuesta

Environmental variations can significantly influence how populations compete for resources, and hence shape their evolution. Here, we study population dynamics subject to a fluctuating environment modeled by a varying carrying capacity…

Populations and Evolution · Quantitative Biology 2023-04-14 Ami Taitelbaum , Robert West , Mauro Mobilia , Michael Assaf

The probability that an advantageous mutant rises to fixation in a viral quasispecies is investigated in the framework of multi-type branching processes. Whether fixation is possible depends on the overall growth rate of the quasispecies…

Biological Physics · Physics 2016-09-08 Claus O. Wilke

The evolution of cooperation often depends upon population structure, yet nearly all models of cooperation implicitly assume that this structure remains static. This is a simplifying assumption, because most organisms possess genetic traits…

Populations and Evolution · Quantitative Biology 2012-08-03 Simon T. Powers , Alexandra S. Penn , Richard A. Watson

When mutation rates are low, natural selection remains effective, and increasing the mutation rate can give rise to an increase in adaptation rate. When mutation rates are high to begin with, however, increasing the mutation rate may have a…

Populations and Evolution · Quantitative Biology 2012-11-06 Philip Gerrish , Alexandre Colato , Paul Sniegowski