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The fixation probability of a single mutant invading a population of residents is among the most widely-studied quantities in evolutionary dynamics. Amplifiers of natural selection are population structures that increase the fixation…

Populations and Evolution · Quantitative Biology 2020-07-01 Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

The environment in which a population evolves can have a crucial impact on selection. We study evolutionary dynamics in finite populations of fixed size in a changing environment. The population dynamics are driven by birth and death…

Populations and Evolution · Quantitative Biology 2014-09-01 Peter Ashcroft , Philipp M Altrock , Tobias Galla

Evolution occurs in populations of reproducing individuals. It is well known that population structure can affect evolutionary dynamics. Traditionally, natural selection is studied between mutants that differ in reproductive rate, but are…

Populations and Evolution · Quantitative Biology 2021-11-23 Josef Tkadlec , Kamran Kaveh , Krishnendu Chatterjee , Martin A. Nowak

The spatial structure of an evolving population affects which mutations become fixed. Some structures amplify selection, increasing the likelihood that beneficial mutations become fixed while deleterious mutations do not. Other structures…

Although mutations drive the evolutionary process, the rates at which the mutations occur are themselves subject to evolutionary forces. Our purpose here is to understand the role of selection and random genetic drift in the evolution of…

Populations and Evolution · Quantitative Biology 2016-10-27 Ananthu James , Kavita Jain

In evolutionary dynamics, a key measure of a mutant trait's success is the probability that it takes over the population given some initial mutant-appearance distribution. This "fixation probability" is difficult to compute in general, as…

Populations and Evolution · Quantitative Biology 2022-02-18 Alex McAvoy , Benjamin Allen

Different evolutionary models are known to make disparate predictions for the success of an invading mutant in some situations. For example, some evolutionary mechanics lead to amplification of selection in structured populations, while…

Populations and Evolution · Quantitative Biology 2020-07-01 Francisco Herrerías-Azcué , Vicente Pérez-Muñuzuri , Tobias Galla

Natural selection and random drift are competing phenomena for explaining the evolution of populations. Combining a highly fit mutant with a population structure that improves the odds that the mutant spreads through the whole population…

Populations and Evolution · Quantitative Biology 2009-08-14 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

Population structure has been known to substantially affect evolutionary dynamics. Networks that promote the spreading of fitter mutants are called amplifiers of natural selection, and those that suppress the spreading of fitter mutants are…

Physics and Society · Physics 2023-10-26 Jnanajyoti Bhaumik , Naoki Masuda

Evolutionary dynamics on graphs can lead to many interesting and counterintuitive findings. We study the Moran process, a discrete time birth-death process, that describes the invasion of a mutant type into a population of wild-type…

Populations and Evolution · Quantitative Biology 2015-04-23 Laura Hindersin , Arne Traulsen

Evolutionary games on graphs describe how strategic interactions and population structure determine evolutionary success, quantified by the probability that a single mutant takes over a population. Graph structures, compared to the…

Populations and Evolution · Quantitative Biology 2017-05-08 Philipp M. Altrock , Arne Traulsen , Martin A. Nowak

Populations evolve by accumulating advantageous mutations. Every population has some spatial structure that can be modeled by an underlying network. The network then influences the probability that new advantageous mutations fixate.…

Populations and Evolution · Quantitative Biology 2024-01-29 Jakub Svoboda , Soham Joshi , Josef Tkadlec , Krishnendu Chatterjee

Population structure can be modelled by evolutionary graphs, which can have a substantial, but very subtle influence on the fate of the arising mutants. Individuals are located on the nodes of these graphs, competing with each other to…

Populations and Evolution · Quantitative Biology 2018-10-31 Marius Möller , Laura Hindersin , Arne Traulsen

Understanding if and how mutants reach fixation in populations is an important question in evolutionary biology. We study the impact of population growth has on the success of mutants. To systematically understand the effects of growth we…

Populations and Evolution · Quantitative Biology 2017-03-29 Peter Ashcroft , Cassandra E. R. Smith , Matthew Garrod , Tobias Galla

In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global…

Populations and Evolution · Quantitative Biology 2015-03-24 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

We analyze evolutionary dynamics on graphs, where the nodes represent individuals of a population. The links of a node describe which other individuals can be displaced by the offspring of the individual on that node. Amplifiers of…

Populations and Evolution · Quantitative Biology 2016-10-27 Laura Hindersin , Arne Traulsen

Resource are often not uniformly distributed within a population. Spatial variations of concentration of a resource, change the fitness of competing strategies locally. The notion of fitness varying with respect to both genotype and…

Populations and Evolution · Quantitative Biology 2022-04-08 Hossein Nemati , Mohammad Reza Ejtehadi , Kamran Kaveh

We study stochastic evolutionary game dynamics in a population of finite size. Individuals in the population are divided into two dynamically evolving groups. The structure of the population is formally described by a Wright-Fisher type…

Probability · Mathematics 2020-07-01 Timothy Chumley , Ozgur Aydogmus , Anastasios Matzavinos , Alexander Roitershtein

We consider a biological population in which a beneficial mutation is undergoing a selective sweep when a second beneficial mutation arises at a linked locus and we investigate the probability that both mutations will eventually fix in the…

Probability · Mathematics 2008-12-02 Feng Yu , Alison Etheridge , Charles Cuthbertson

In an adapted population of mutators in which most mutations are deleterious, a nonmutator that lowers the mutation rate is under indirect selection and can sweep to fixation. Using a multitype branching process, we calculate the fixation…

Populations and Evolution · Quantitative Biology 2017-09-11 Kavita Jain , Ananthu James
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