English
Related papers

Related papers: A colloid approach to self-assembling antibodies

200 papers

Within the framework of a discrete Gaussian model, we present analytical results for the interaction induced by a lamellar phase between small embedded colloids. We consider the two limits of particles strongly adherent to the adjacent…

Interparticle interactions and bulk properties of colloidal suspensions can be substantially modified by addition of nanoparticles. Extreme asymmetries in size and charge between colloidal particles and nanoparticles present severe…

Soft Condensed Matter · Physics 2018-01-03 Alan R. Denton

Mixtures of active and passive particles are predicted to exhibit a variety of nonequilibrium phases. Here we report a dynamic clustering phase in mixtures of colloids and motile bacteria. We show that colloidal clustering results from a…

Soft Condensed Matter · Physics 2022-05-25 Shreyas Gokhale , Junang Li , Alexandre Solon , Jeff Gore , Nikta Fakhri

We study the structural and thermodynamic properties of patchy particle liquids, with a special focus on the role of "color", i.e. specific interactions between individual patches. A possible experimental realization of such "chromatic"…

Soft Condensed Matter · Physics 2015-07-22 Oleg A. Vasilyev , Boris A. Klumov , Alexei V. Tkachenko

Building structures with hierarchical order through the self-assembly of smaller blocks is not only a prerogative of nature, but also a strategy to design artificial materials with tailored functions. We explore in simulation the…

Soft Condensed Matter · Physics 2020-02-17 Santi Prestipino , Domenico Gazzillo , Gianmarco Munaò , Dino Costa

Liquid mixtures of many interacting components often exhibit numerous coexisting types of droplets. An exciting example is the cytosol of biological cells, where diverse droplets, called condensates, are essential for cellular function.…

Soft Condensed Matter · Physics 2025-05-28 Yicheng Qiang , Chengjie Luo , David Zwicker

The formation of self assembled structures such as micelles has been intensively studied and is well understood. The ability of a solution of amphiphilic molecules to develop micelles is depending on the concentration and characterized by…

Soft Condensed Matter · Physics 2019-05-13 Simon Raschke , Andreas Heuer

Particle-based simulations are performed to study the post-relaxation dynamics of functionalized (patchy) colloids adsorbed on an attractive substrate. Kinetically arrested structures that depend on the number of adsorbed particles and the…

Soft Condensed Matter · Physics 2015-09-02 C. S. Dias , C. Braga , N. A. M. Araujo , M. M. Telo da Gama

In this paper, we explore experimentally the phase behavior of a dense active suspension of self- propelled colloids. In addition to a solid-like and a gas-like phase observed for high and low densities, a novel cluster phase is reported at…

Soft Condensed Matter · Physics 2015-06-04 I. Theurkauff , C. Cottin-Bizonne , J. Palacci , C. Ybert , L. Bocquet

Protein assembly plays an important role throughout all phyla of life, both physiologically and pathologically. In particular, aggregation and polymerization of proteins are key-strategies that regulate cellular function. In recent years,…

We investigate the response of a dense monodisperse quasi-two-dimensional (q2D) colloid suspension when a particle is dragged by a constant velocity optical trap. Consistent with microrheological studies of other geometries, the…

Entropy alone can self-assemble hard particles into colloidal crystals of remarkable complexity whose structures are the same as atomic and molecular crystals, but with larger lattice spacings. Although particle-based molecular simulation…

Soft Condensed Matter · Physics 2021-07-06 Thi Vo , Sharon C. Glotzer

DNA-coated particles are promising as building blocks for functional and finite-sized assemblies because they can be programmed with orthogonal interactions owing to the sequence-specific hybridization of DNA strands. To fully exploit this…

Soft Condensed Matter · Physics 2026-04-17 T. C. M. Stevens , A. van der Sluis , I. K. Voets , P. G. Moerman

Complex nonequilibrium self-assembly enables the formation of materials with specific patterns and functions from the bottom up. How to directionally control the assembly to form the target configuration is a challenge. Here, we propose a…

Soft Condensed Matter · Physics 2026-01-29 Chaoqun Du , Zhiyu Cao , Zhonghuai Hou

We study the depletion-induced self-assembly of indented colloids. Using state-of-the-art Monte Carlo simulation techniques that treat the depletant particles explicitly, we demonstrate that colloids assemble by a lock-and-key mechanism,…

Soft Condensed Matter · Physics 2014-01-13 Douglas J. Ashton , Robert L. Jack , Nigel B. Wilding

In the present study we are performing simulation of simple model of two patch colloidal particles undergoing irreversible diffusion limited cluster aggregation using patchy Brownian cluster dynamics. In addition to the irreversible…

Soft Condensed Matter · Physics 2017-10-26 Isha Malhotra , Sujin B. Babu

The development of therapeutic antibodies heavily relies on accurate predictions of how antigens will interact with antibodies. Existing computational methods in antibody design often overlook crucial conformational changes that antigens…

Quantitative Methods · Quantitative Biology 2025-03-05 Cheng Tan , Yijie Zhang , Zhangyang Gao , Yufei Huang , Haitao Lin , Lirong Wu , Fandi Wu , Mathieu Blanchette , Stan. Z. Li

Colloidal aggregation could be implemented in various fields ranging from purely colloidal thermodynamics to protein interactions, their stability, and maybe folding. Indeed, colloidal aggregation is closely linked to the so-called…

Soft Condensed Matter · Physics 2013-01-03 Pierre de Thier

Patchy colloidal platelets with convex, non-spherical shapes have been realized with different materials at length scales ranging from nanometers to microns. While the assembly of these hard shapes tends to maximize edge-to-edge contacts,…

Soft Condensed Matter · Physics 2020-04-22 Carina Karner , Christoph Dellago , Emanuela Bianchi

Nano- to micro-sized particles with differently charged surface areas exhibit complex interaction patterns, characterized by both opposite-charge attraction and like-charge repulsion. While several successful models have been proposed in…

Soft Condensed Matter · Physics 2025-01-16 Daniele Notarmuzi , Silvano Ferrari , Emanuele Locatelli , Emanuela Bianchi