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We investigate whether temporal embedding models trained on longitudinal electronic health records can learn clinically meaningful representations without compromising predictive performance, and how architectural choices affect embedding…

Machine Learning · Computer Science 2026-04-17 Aditya Kumar , Mario A. Cypko , Oliver Amft

Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of…

Machine Learning · Computer Science 2020-11-18 Jinghe Zhang , Kamran Kowsari , Mehdi Boukhechba , James Harrison , Jennifer Lobo , Laura Barnes

Chronic Kidney Disease (CKD) represents a significant global health challenge, characterized by the progressive decline in renal function, leading to the accumulation of waste products and disruptions in fluid balance within the body. Given…

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

Clinical medical data, especially in the intensive care unit (ICU), consist of multivariate time series of observations. For each patient visit (or episode), sensor data and lab test results are recorded in the patient's Electronic Health…

Machine Learning · Computer Science 2017-03-23 Zachary C. Lipton , David C. Kale , Charles Elkan , Randall Wetzel

Chronic kidney disease (CKD) has a poor prognosis due to excessive risk factors and comorbidities associated with it. The early detection of CKD faces challenges of insufficient medical histories of positive patients and complicated risk…

Machine Learning · Computer Science 2020-12-08 Yu Wang , Ziqiao Guan , Wei Hou , Fusheng Wang

This study explores the potential of utilizing administrative claims data, combined with advanced machine learning and deep learning techniques, to predict the progression of Chronic Kidney Disease (CKD) to End-Stage Renal Disease (ESRD).…

Machine Learning · Computer Science 2024-10-28 Yubo Li , Saba Al-Sayouri , Rema Padman

Chronic Kidney Disease (CKD) constitutes a major global medical burden, marked by the gradual deterioration of renal function, which results in the impaired clearance of metabolic waste and disturbances in systemic fluid homeostasis. Owing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anas Bin Ayub , Nilima Sultana Niha , Md. Zahurul Haque

Clinical measurements collected over time are naturally represented as multivariate time series (MTS), which often contain missing data. An autoencoder can learn low dimensional vectorial representations of MTS that preserve important data…

Neural and Evolutionary Computing · Computer Science 2017-10-23 Filippo Maria Bianchi , Karl Øyvind Mikalsen , Robert Jenssen

Computed tomography (CT) imaging could be very practical for diagnosing various diseases. However, the nature of the CT images is even more diverse since the resolution and number of the slices of a CT scan are determined by the machine and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-11 Chih-Chung Hsu , Chi-Han Tsai , Guan-Lin Chen , Sin-Di Ma , Shen-Chieh Tai

As the global population ages, the incidence of Chronic Kidney Disease (CKD) is rising. CKD often remains asymptomatic until advanced stages, which significantly burdens both the healthcare system and patient quality of life. This research…

Artificial Intelligence · Computer Science 2024-04-18 Nantika Nguycharoen

Chronic kidney disease (CKD) is a significant public health challenge, often progressing to end-stage renal disease (ESRD) if not detected and managed early. Early intervention, warranted by silent disease progression, can significantly…

Machine Learning · Computer Science 2024-11-19 Zachary Dana , Ahmed Ammar Naseer , Botros Toro , Sumanth Swaminathan

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, unified way for prediction purposes. It is…

Machine Learning · Computer Science 2020-09-22 D. Kollias , N. Bouas , Y. Vlaxos , V. Brillakis , M. Seferis , I. Kollia , L. Sukissian , J. Wingate , S. Kollias

Longitudinal imaging is capable of capturing the static ana\-to\-mi\-cal structures and the dynamic changes of the morphology resulting from aging or disease progression. Self-supervised learning allows to learn new representation from…

Image and Video Processing · Electrical Eng. & Systems 2019-10-25 Antoine Rivail , Ursula Schmidt-Erfurth , Wolf-Dieter Vogl , Sebastian M. Waldstein , Sophie Riedl , Christoph Grechenig , Zhichao Wu , Hrvoje Bogunović

When deep learning models are sequentially trained on new data, they tend to abruptly lose performance on previously learned tasks, a critical failure known as catastrophic forgetting. This challenge severely limits the deployment of AI in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Paraskevi-Antonia Theofilou , Anuhya Thota , Stefanos Kollias , Mamatha Thota

Koopman representations aim to learn features of nonlinear dynamical systems (NLDS) which lead to linear dynamics in the latent space. Theoretically, such features can be used to simplify many problems in modeling and control of NLDS. In…

Machine Learning · Computer Science 2023-11-27 Mahan Fathi , Clement Gehring , Jonathan Pilault , David Kanaa , Pierre-Luc Bacon , Ross Goroshin

Chronic Kidney Disease (CKD) is one of the widespread Chronic diseases with no known ultimo cure and high morbidity. Research demonstrates that progressive Chronic Kidney Disease (CKD) is a heterogeneous disorder that significantly impacts…

Machine Learning · Computer Science 2025-01-28 K M Tawsik Jawad , Anusha Verma , Fathi Amsaad , Lamia Ashraf

Access to real-world healthcare data is limited by stringent privacy regulations and data imbalances, hindering advancements in research and clinical applications. Synthetic data presents a promising solution, yet existing methods often…

Machine Learning · Computer Science 2025-03-11 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang
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