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A celebrated and controversial hypothesis conjectures that some biological systems --parts, aspects, or groups of them-- may extract important functional benefits from operating at the edge of instability, halfway between order and…

Statistical Mechanics · Physics 2018-08-01 Miguel A. Munoz

Human brains and bodies are not hardware running software: the hardware is the software. We reason that because the microscopic physics of artificial-intelligence hardware and of human biological "hardware" is distinct, neuromorphic…

Emerging Technologies · Computer Science 2024-12-12 Jeremie Laydevant , Logan G. Wright , Tianyu Wang , Peter L. McMahon

The evolution of complexity has been a central theme for Biology [2] and Artificial Life research [1]. It is generally agreed that complexity has increased in our universe, giving way to life, multi-cellularity, societies, and systems of…

Populations and Evolution · Quantitative Biology 2011-09-06 Carlos Gershenson , Tom Lenaerts

The next decade will be an exciting time for computational physicists. After 50 years of being forced to use standardized commercial equipment, it will finally become relatively straightforward to adapt one's computing tools to one's own…

Astrophysics · Physics 2007-05-23 Toshiyuki Fukushige , Piet Hut , Jun Makino

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

Light microscopy allows observing cellular features and objects with sub-micrometer resolution. As such, light microscopy has been playing a fundamental role in the life sciences for more than a hundred years. Fueled by the availability of…

Other Quantitative Biology · Quantitative Biology 2021-10-28 Johannes Hohlbein , Benedict Diederich , Barbora Marsikova , Emmanuel G. Reynaud , Seamus Holden , Wiebke Jahr , Robert Haase , Kirti Prakash

Modern research in the life sciences is unthinkable without computational methods for extracting, quantifying and visualizing information derived from biological microscopy imaging data. In the past decade, we observed a dramatic increase…

Reproducibility should be a cornerstone of science as it enables validation and reuse. In recent years, the scientific community and the general public became increasingly aware of the reproducibility crisis, i.e. the wide-spread inability…

Human-Computer Interaction · Computer Science 2020-12-07 Sebastian Stefan Feger

With the incremental development of robotic platforms to automate the manual processes, path planning has become a critical domain with or without the knowledge of the indoor and outdoor environment. The algorithms can be intelligent or…

Robotics · Computer Science 2020-12-22 R. N. Somarathna

The rapid growth and diversity in service offerings and the ensuing complexity of information technology ecosystems present numerous management challenges (both operational and strategic). Instrumentation and measurement technology is, by…

Software Engineering · Computer Science 2012-06-26 Moises Goldszmidt

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

Recent advances in artificial intelligence (AI) and machine learning have created a general perception that AI could be used to solve complex problems, and in some situations over-hyped as a tool that can be so easily used. Unfortunately,…

Artificial Intelligence · Computer Science 2018-04-27 Jinyang Gao , Wei Wang , Meihui Zhang , Gang Chen , H. V. Jagadish , Guoliang Li , Teck Khim Ng , Beng Chin Ooi , Sheng Wang , Jingren Zhou

Computing in the life sciences has undergone a transformative evolution, from early computational models in the 1950s to the applications of artificial intelligence (AI) and machine learning (ML) seen today. This paper highlights key…

Other Quantitative Biology · Quantitative Biology 2024-06-21 Samuel A. Donkor , Matthew E. Walsh , Alexander J. Titus

Biophysics is a subject that is spread over many disciplines and transcends the skills and knowledge of the individual student. This makes it challenging both to teach and to learn. Educational materials are described to aid in teaching…

Physics Education · Physics 2015-06-15 J. M. Deutsch

Emerging data-driven scientific workflows are seeking to leverage distributed data sources to understand end-to-end phenomena, drive experimentation, and facilitate important decision-making. Despite the exponential growth of available…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-10 Manish Parashar

Several abilities of biological systems, such as adaptation to natural environment, or of animals to learn patterns when appropriately trained, are features that are extremely useful, if emulated by electronic circuits, in applications…

Neurons and Cognition · Quantitative Biology 2011-12-22 M. Di Ventra , Y. V. Pershin

The emergence of "big data" offers unprecedented opportunities for not only accelerating scientific advances but also enabling new modes of discovery. Scientific progress in many disciplines is increasingly enabled by our ability to examine…

Computers and Society · Computer Science 2017-07-03 Vasant G. Honavar , Mark D. Hill , Katherine Yelick

The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive…

Emerging Technologies · Computer Science 2025-11-04 Yannic Talavera , Bernd Ulmann

In today's world of big data, computational analysis has become a key driver of biomedical research. Recent exponential growth in the volume of available omics data has reshaped the landscape of contemporary biology, creating demand for a…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-09 Jaqueline J. Brito , Thiago Mosqueiro , Jeremy Rotman , Victor Xue , Douglas J. Chapski , Juan De la Hoz , Paulo Matias , Lana Martin , Alex Zelikovsky , Matteo Pellegrinni , Serghei Mangul

Today, people use multiple devices to fulfill their information needs. However, designers design each device individually, without accounting for the other devices that users may also use. In many cases, the applications on all these…

Human-Computer Interaction · Computer Science 2007-05-23 Manas Tungare , Pardha S. Pyla , Manuel Pérez-Quiñones , Steve Harrison
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