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Soft biological tissues exhibit a tendency to maintain a preferred state of tensile stress, known as tensional homeostasis, which is restored even after external mechanical stimuli. This macroscopic behavior can be described using the…

Machine Learning · Computer Science 2025-01-23 Hagen Holthusen , Tim Brepols , Kevin Linka , Ellen Kuhl

Cells and tissues change shape both to carry out their function and during pathology. In most cases, these deformations are driven from within the systems themselves. This is permitted by a range of molecular actors, such as active…

Biological Physics · Physics 2022-10-18 Alexander Erlich , Jocelyn Étienne , Jonathan Fouchard , Tom Wyatt

Self-assembly of protein monomers into distinct membrane protein oligomers provides a general mechanism for diversity in the molecular architectures, and resulting biological functions, of membrane proteins. We develop a general physical…

Biomolecules · Quantitative Biology 2016-11-29 Osman Kahraman , Christoph A. Haselwandter

Cells coexist together in colonies or as tissues. Their behaviour is controlled by an interplay between intercellular forces and biochemical regulation. We develop a simple model of the cell cycle, the fundamental regulatory network…

Biological Physics · Physics 2021-08-04 Jintao Li , Simon K. Schnyder , Matthew S. Turner , Ryoichi Yamamoto

Developing tissues often maintain mechanical coherence while continuously remodeling through cellular processes such as cell divisions and rearrangements. In this way, they are an example of amorphous solids. In passive amorphous solids,…

Soft Condensed Matter · Physics 2026-05-13 Ali Tahaei , Ahandeep Manna , Marko Popović

In this report it is approched the Contest dynamics as mathematical theory, therefore applicable to all contest sports. Starting with the physical definition of Athlete and Couple of Athlete systems and after singling out the interaction…

General Physics · Physics 2008-06-26 Attilio Sacripanti

Microscopic biological systems operate far from equilibrium, are subject to strong fluctuations, and are composed of many coupled components with interactions varying in nature and strength. Researchers are actively investigating the…

Statistical Mechanics · Physics 2023-12-25 Emma Lathouwers , David A. Sivak

Mechanical forces influence the development and behavior of biological tissues. In many situations these forces are exerted or resisted by elastic compliant structures such as the own-tissue cellular matrix or other surrounding tissues.…

The mechanisms leading cells to acquire a fitness advantage and establish themselves in a population are paramount to understanding the development and growth of cancer. Although there are many works that study separately either the…

Biological Physics · Physics 2024-05-14 Louis Brezin , Kirill S. Korolev

Tissue mechanical properties such as rigidity and fluidity, and changes in these properties driven by jamming-unjamming transitions (UJT), have come under recent highlight as mechanical markers of health and disease in various biological…

Soft Condensed Matter · Physics 2022-10-18 Gudur Ashrith Reddy , Parag Katira

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

During morphogenesis, the shape of a tissue emerges from collective cellular behaviors, which are in part regulated by mechanical and biochemical interactions between cells. Quantification of force and stress is therefore necessary to…

Tissues and Organs · Quantitative Biology 2014-02-19 K. Sugimura , Y. Bellaïche , F. Graner , P. Marcq , S. Ishihara

In many adult tissues, stem cells and differentiated cells are not homogeneously distributed : stem cells are arranged in periodic "niches", and differentiated cells are constantly produced and migrate out of these niches. In this article,…

Biological Physics · Physics 2016-03-23 Edouard Hannezo , Alice Coucke , Jean-François Joanny

A microscopic model is developed, within the frame of the theory of quantitative traits, to study both numerically and analytically the combined effect of competition and assortativity on the sympatric speciation process, i.e. speciation in…

Populations and Evolution · Quantitative Biology 2007-05-23 Franco Bagnoli , Carlo Guardiani

A new phase field model of microstructural evolution is presented that includes the effects of elastic strain energy. The model's thin interface behavior is investigated by mapping it onto a recent model developed by Echebarria et al (Phys…

Materials Science · Physics 2008-10-29 Michael Greenwood , Jeffrey J. Hoyt , Nikolas Provatas

The statistical mechanics of equilibrium interfaces has been well-established for over a half century. In the last decade, a wealth of observations have made increasingly clear that a new perspective is required to describe interfaces…

Soft Condensed Matter · Physics 2025-04-21 Luke Langford , Ahmad K. Omar

The search for universal laws that help establish a relationship between dynamics and computation is driven by recent expansionist initiatives in biologically inspired computing. A general setting to understand both such dynamics and…

Machine Learning · Computer Science 2020-09-17 G Manjunath

Ecological trade-offs between species are often invoked to explain species coexistence in ecological communities. However, few mathematical models have been proposed for which coexistence conditions can be characterized explicitly in terms…

Populations and Evolution · Quantitative Biology 2013-05-21 Bart Haegeman , Tewfik Sari , Rampal S. Etienne

Virtually every biological function emerges through the organization of molecules in time and space. Consequently, a major challenge in statistical physics is to uncover the universal principles governing macromolecular self-organization…

Statistical Mechanics · Physics 2026-03-16 E. Meyberg , J. F. Robinson , T. Speck

While mechanobiology has demonstrated that precise control over mechanical properties at the whole-cell level is crucial for many biological functions, comparatively little attention has been paid to the intracellular mechanical properties.…

Subcellular Processes · Quantitative Biology 2025-01-27 Mohammad Amin Eskandari , Jannis Fischer , Noémie Veyret , Dorian Marx , Timo Betz