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Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Non-negative matrix factorization (NMF) is a recently developed technique for finding parts-based, linear representations of non-negative data. Although it has successfully been applied in several applications, it does not always result in…

Machine Learning · Computer Science 2007-05-23 Patrik O. Hoyer

Community is a fundamental and critical characteristic of an undirected social network, making community detection be a vital yet thorny issue in network representation learning. A symmetric and non-negative matrix factorization (SNMF)…

Social and Information Networks · Computer Science 2023-02-24 Zhigang Liu , Xin Luo

We introduce a new method based on nonnegative matrix factorization, Neural NMF, for detecting latent hierarchical structure in data. Datasets with hierarchical structure arise in a wide variety of fields, such as document classification,…

Machine Learning · Computer Science 2023-03-02 Tyler Will , Runyu Zhang , Eli Sadovnik , Mengdi Gao , Joshua Vendrow , Jamie Haddock , Denali Molitor , Deanna Needell

Non-negative matrix factorization (NMF) has previously been shown to be a useful decomposition for multivariate data. We interpret the factorization in a new way and use it to generate missing attributes from test data. We provide a joint…

Numerical Analysis · Computer Science 2010-07-05 Mithun Das Gupta

Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He

Nonnegative matrix factorization (NMF) is one of the most frequently-used matrix factorization models in data analysis. A significant reason to the popularity of NMF is its interpretability and the `parts of whole' interpretation of its…

Machine Learning · Computer Science 2018-01-19 Sanjar Karaev , James Hook , Pauli Miettinen

Mortality risk is a major concern to patients have just been discharged from the intensive care unit (ICU). Many studies have been directed to construct machine learning models to predict such risk. Although these models are highly…

Applications · Statistics 2021-01-20 Eugene T. Y. Ang , Milashini Nambiar , Yong Sheng Soh , Vincent Y. F. Tan

In this work we perform some mathematical analysis on non-negative matrix factorizations (NMF) and apply NMF to some imaging and inverse problems. We will propose a sparse low-rank approximation of big positive data and images in terms of…

Optimization and Control · Mathematics 2015-04-24 Yat Tin Chow , Kazufumi Ito , Jun Zou

We present neural frailty machine (NFM), a powerful and flexible neural modeling framework for survival regressions. The NFM framework utilizes the classical idea of multiplicative frailty in survival analysis to capture unobserved…

Machine Learning · Computer Science 2023-10-05 Ruofan Wu , Jiawei Qiao , Mingzhe Wu , Wen Yu , Ming Zheng , Tengfei Liu , Tianyi Zhang , Weiqiang Wang

The symmetric Nonnegative Matrix Factorization (NMF), a special but important class of the general NMF, has found numerous applications in data analysis such as various clustering tasks. Unfortunately, designing fast algorithms for the…

Machine Learning · Computer Science 2023-01-26 Xiao Li , Zhihui Zhu , Qiuwei Li , Kai Liu

Accurate mortality prediction allows Intensive Care Units (ICUs) to adequately benchmark clinical practice and identify patients with unexpected outcomes. Traditionally, simple statistical models have been used to assess patient death risk,…

Machine Learning · Computer Science 2020-05-20 William Caicedo-Torres , Jairo Gutierrez

Nonnegative Matrix Factorization consists in (approximately) factorizing a nonnegative data matrix by the product of two low-rank nonnegative matrices. It has been successfully applied as a data analysis technique in numerous domains, e.g.,…

Optimization and Control · Mathematics 2012-08-13 Nicolas Gillis , François Glineur

Hyperspectral unmixing (HU) is a critical yet challenging task in remote sensing. However, existing nonnegative matrix factorization (NMF) methods with graph learning mostly focus on first-order or second-order nearest neighbor…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Hui Chen , Liangyu Liu , Xianchao Xiu , Wanquan Liu

Nonnegative matrix factorization (NMF) is a powerful technique for dimension reduction, extracting latent factors and learning part-based representation. For large datasets, NMF performance depends on some major issues: fast algorithms,…

Optimization and Control · Mathematics 2015-07-01 Duy-Khuong Nguyen , Tu-Bao Ho

As standards of care advance, patients are living longer and once-fatal diseases are becoming manageable. Clinical trials increasingly focus on reducing disease burden, which can be quantified by the timing and occurrence of multiple…

Nonnegative matrix factorization (NMF) is a relatively new unsupervised learning algorithm that decomposes a nonnegative data matrix into a parts-based, lower dimensional, linear representation of the data. NMF has applications in image…

Machine Learning · Statistics 2020-12-08 Matthew Corsetti , Ernest Fokoué

Non-negative Matrix Factorization (NMF) is a key kernel for unsupervised dimension reduction used in a wide range of applications, including topic modeling, recommender systems and bioinformatics. Due to the compute-intensive nature of…

Machine Learning · Computer Science 2019-04-18 Gordon E. Moon , Aravind Sukumaran-Rajam , Srinivasan Parthasarathy , P. Sadayappan

Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

Nonnegative matrix factorization (NMF) is a linear dimensionality reduction technique for nonnegative data, with applications such as hyperspectral unmixing and topic modeling. NMF is a difficult problem in general (NP-hard), and its…

Numerical Analysis · Mathematics 2025-11-11 Junjun Pan , Valentin Leplat , Michael Ng , Nicolas Gillis