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This study investigates the utilization of various mathematical models for comprehending and managing outbreaks of infectious diseases, with a specific focus on how different distributions of incubation times influence predictions regarding…

Adaptation and Self-Organizing Systems · Physics 2024-03-08 Eric Rozan , Marcelo N Kuperman , Sebastian Bouzat

Epidemiological delays, such as incubation periods, serial intervals, and hospital lengths of stay, are among key quantities in infectious disease epidemiology that inform public health policy and clinical practice. This information is used…

In the wake of the 2020 COVID-19 epidemic, much work has been performed on the development of mathematical models for the simulation of the epidemic, and of disease models generally. Most works follow the susceptible-infected-removed (SIR)…

Numerical Analysis · Mathematics 2022-05-18 Nicola Guglielmi , Elisa Iacomini , Alex Viguerie

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

By convention, and even more often, as an unintentional consequence of design, time distributions of latency and infectious durations in stochastic epidemic simulations are often exponential. The skewed distribtion typically leads to…

Quantitative Methods · Quantitative Biology 2007-12-18 Martin Camitz , Ake Svensson

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

In order to simulate the spread of infectious diseases, many epidemiological models use systems of ordinary differential equations (ODEs) to describe the underlying dynamics. These models incorporate the implicit assumption, that the stay…

Dynamical Systems · Mathematics 2025-10-13 Lena Plötzke , Anna Wendler , René Schmieding , Martin J. Kühn

We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control…

Systems and Control · Electrical Eng. & Systems 2022-11-21 Tamas G. Molnar , Andrew W. Singletary , Gabor Orosz , Aaron D. Ames

Delayed processes are ubiquitous in biological systems and are often characterized by delay differential equations (DDEs) and their extension to include stochastic effects. DDEs do not explicitly incorporate intermediate states associated…

Quantitative Methods · Quantitative Biology 2016-09-28 Jingchen Feng , Stuart Sevier , Bin Huang , Dongya Jia , Herbert Levine

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

Ordinary differential equations (ODE) are a popular tool to model the spread of infectious diseases, yet they implicitly assume an exponential distribution to describe the flow from one infection state to another. However, scientific…

Numerical Analysis · Mathematics 2025-10-13 Anna Wendler , Lena Plötzke , Hannah Tritzschak , Martin J. Kühn

We present a modified \emph{susceptible-infected-susceptible} (SIS) model on complex networks, small-world and scale-free, to study epidemic spreading with the effect of time delay which is introduced to the infected phase. Considering the…

Physics and Society · Physics 2009-11-11 Xin-Jian Xu , Hai-Ou Peng , Xiao-Mei Wang , Ying-Hai Wang

Infectious diseases are among the most prominent threats to mankind. When preventive health care cannot be provided, a viable means of disease control is the isolation of individuals, who may be infected. To study the impact of isolation,…

Dynamical Systems · Mathematics 2018-04-10 Stefan Ruschel , Tiago Pereira , Serhiy Yanchuk , Lai-Sang Young

This paper analyses the dynamics of infectious disease with a concurrent spread of disease awareness. The model includes local awareness due to contacts with aware individuals, as well as global awareness due to reported cases of infection…

Populations and Evolution · Quantitative Biology 2017-04-21 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

Populations and Evolution · Quantitative Biology 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou

Predicting the evolution of diseases is challenging, especially when the data availability is scarce and incomplete. The most popular tools for modelling and predicting infectious disease epidemics are compartmental models. They stratify…

Machine Learning · Computer Science 2023-10-10 Esha Saha , Lam Si Tung Ho , Giang Tran

Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…

Populations and Evolution · Quantitative Biology 2021-11-23 Gabriel Turinici

Understanding the timing of the peak of a disease outbreak forms an important part of epidemic forecasting. In many cases, such information is essential for planning increased hospital bed demand and for designing of public health…

Populations and Evolution · Quantitative Biology 2023-11-27 Jacob Curran-Sebastian , Lorenzo Pellis , Ian Hall , Thomas House
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