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There are a great many proteins that localize to and collectively generate curvature in biological fluid membranes. We study changes in the topology of fluid membranes due to the presence of highly anisotropic, curvature-inducing proteins.…

Soft Condensed Matter · Physics 2015-05-19 Kiyotaka Akabori , C. D. Santangelo

A remarkable property of flexible self-avoiding elastic surfaces (membranes) is that they remain flat at all temperatures, even in the absence of a bending rigidity or in the presence of active fluctuations. Here, we report numerical…

Soft Condensed Matter · Physics 2025-01-14 A. D. Chen , M. C. Gandikota , A. Cacciuto

The detachment dynamics of a fluid membrane with an isotropic spontaneous curvature from a flat substrate are studied by using meshless membrane simulations. The membrane is detached from an open edge leading to vesicle formation. With…

Soft Condensed Matter · Physics 2019-11-11 Hiroshi Noguchi

When a thin elastic sheet is confined to a region much smaller than its size the morphology of the resulting crumpled membrane is a network of straight ridges or folds that meet at sharp vertices. A virial theorem predicts the ratio of the…

Condensed Matter · Physics 2009-10-28 Alexander E. Lobkovsky , T. A. Witten

The buckling instabilities of core-shell systems, comprising an interior elastic sphere, attached to an exterior shell, have been proposed to underlie myriad biological morphologies. To fully discuss such systems, however, it is important…

Soft Condensed Matter · Physics 2023-07-12 Yingzhen Tian , Megan McCarthy , Megan King , S. G. J. Mochrie

Many biological tissues feature a heterogeneous network of fibers whose tensile and bending rigidity contribute substantially to these tissues' elastic properties. Rigidity percolation has emerged as a important paradigm for relating these…

When a flexible filament is confined to a fluid interface, the balance between capillary attraction, bending resistance, and tension from an external source can lead to a self-buckling instability. We perform an analysis of this instability…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Saverio E. Spagnolie , Denis Bartolo , Eric Lauga

We report experiments on the deformation and transport of an elastic fiber in a viscous cellular flow, namely a lattice of counter-rotative vortices. We show that the fiber can buckle when approaching a stagnation point. By tuning either…

Soft Condensed Matter · Physics 2010-03-31 E. Wandersman , N. Quennouz , M. Fermigier , A. Lindner , O. du Roure

A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the…

Biological Physics · Physics 2018-12-26 T. A. Engstrom , Teng Zhang , A. K. Lawton , A. L. Joyner , J. M. Schwarz

A phase diagram for a one dimensional fiber bundle model is constructed with a continuous variation in two parameters guiding dynamics of the model: strength of disorder and system size. We monitor the successive events of fiber rupture in…

Statistical Mechanics · Physics 2021-12-03 Subhadeep Roy

In studying structural inter-connections in the human brain, it is common to first estimate fiber bundles connecting different regions of the brain relying on diffusion MRI. These fiber bundles act as highways for neural activity and…

Applications · Statistics 2016-12-06 Zhengwu Zhang , Maxime Descoteaux , David B. Dunson

We present a novel mathematical approach to model noise in dynamical systems. We do so by considering dynamics of a chain of diffusively coupled Nagumo cells affected by noise. We show that the noise in transmembrane current can be…

Dynamical Systems · Mathematics 2011-05-13 A. A. Samoletov , B. N. Vasiev

We investigate the elasticity of unsupported epithelial monolayer and we discover that unlike a thin solid plate, which wrinkles if geometrically incompatible with the underlying substrate, the epithelium may do so even in absence of the…

Soft Condensed Matter · Physics 2023-05-24 Urška Andrenšek , Primož Ziherl , Matej Krajnc

Real cortical tissue curves and folds according to experimental data. However, our current simulations only use unfolded cortical layers. This project extends the cortical slice model in order to be able to specify arbitrary curvatures to…

Neurons and Cognition · Quantitative Biology 2014-05-15 Jintao Long , Richard Tomsett , Marcus Kaiser

first-principles numerical simulation model for crumpling of a stiff tethered membrane is introduced. In our model membranes, wrinkles, ridge formation, ridge collapse, as well as the initiation of stiffness divergence, are observed. The…

Soft Condensed Matter · Physics 2015-06-24 J. A. Astrom , J. Timonen , Mikko Karttunen

Bundles of stiff filaments are ubiquitous in the living world, found both in the cytoskeleton and in the extracellular medium. These bundles are typically held together by smaller cross-linking molecules. We demonstrate analytically,…

The buckling and twisting of slender, elastic fibers is a deep and well-studied field. A slender elastic rod that is twisted with respect to a fixed end will spontaneously form a loop, or hockle, to relieve the torsional stress that builds.…

Soft Condensed Matter · Physics 2021-08-03 Adam Fortais , Elsie Loukiantchenko , Kari Dalnoki-Veress

Statistical ensembles of flexible two-dimensional fluid membranes arise naturally in the description of many physical systems. Typically one encounters such systems in a regime of low tension but high stiffness against bending, which is…

Condensed Matter · Physics 2016-08-31 Philip Nelson , Thomas Powers

Thin shells are characterized by a high cost of stretching compared to bending. As a result isometries of the midsurface of a shell play a crucial role in their mechanics. In turn, curves with zero normal curvature play a critical role in…

Soft Condensed Matter · Physics 2018-06-05 Salem Al Mosleh , Christian Santangelo

Vortex filament model has become a standard and powerful tool to visualize the motion of quantized vortices in helium superfluids. In this article, we present an overview of the method and highlight its impact in aiding our understanding of…

Other Condensed Matter · Physics 2014-04-29 Risto Hänninen , Andrew W. Baggaley